Murcko scaffold
Maleimide scaffold
637 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 7
- Chemicals
- 637
- With full pages
- 87
Scaffold SMILES
O=C1C=CC(=O)N1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 529 to 576 of 637 chemicals
(2R)-3-(((2-(3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)ethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl dipalmitate
CAS 1633047-04-7C44H79N2O11P
Dspe-mal
CAS 1360858-99-6C48H87N2O11P
Dope-mal
CAS 2295813-15-7C48H83N2O11P
Mal-amido-PEG8-val-gly
CAS 2353409-54-6C33H56N4O15
1-(3-Azidopropyl)-1H-pyrrole-2,5-dione
CAS 896465-45-5C7H8N4O2
MC(C5)-Val-Cit
CAS 2504147-59-3C20H32N6O6
(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl)-L-alanyl-L-alanyl-L-asparagine
CAS 3052713-76-2C20H29N5O8
2-(3-Hexyl-2,5-dihydro-4-methyl-2,5-dioxo-1H-pyrro
CAS 2431889-83-5C16H23NO6
![tert-Butyl N-[2-[4-(2,5-dioxopyrrol-1-yl)butanoylamino]ethyl]-N-methylcarbamate chemical structure, C16H25N3O5, CAS 1404071-91-5](/s/WLHMFDPPSDNDLQ-UHFFFAOYSA-N.svg)
tert-Butyl N-[2-[4-(2,5-dioxopyrrol-1-yl)butanoylamino]ethyl]-N-methylcarbamate
CAS 1404071-91-5C16H25N3O5
![tert-Butyl N-[2-[4-(2,5-dioxopyrrol-1-yl)butanoyl-methylamino]ethyl]carbamate chemical structure, C16H25N3O5, CAS 1404071-88-0](/s/QYNRSKYRKGTAMT-UHFFFAOYSA-N.svg)
tert-Butyl N-[2-[4-(2,5-dioxopyrrol-1-yl)butanoyl-methylamino]ethyl]carbamate
CAS 1404071-88-0C16H25N3O5
![tert-Butyl N-[2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]ethyl]carbamate chemical structure, C17H27N3O5, CAS 640267-51-2](/s/UDQAHBMEKGVAEZ-UHFFFAOYSA-N.svg)
tert-Butyl N-[2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]ethyl]carbamate
CAS 640267-51-2C17H27N3O5
tert-Butyl (2-(3,4-dimethyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)carbamate
CAS 445423-56-3C13H20N2O4
Mal-PEG5-NH-Boc
CAS 2170654-72-3C21H36N2O9
Mal-PEG5-amine TFA salt
CAS 2170654-73-4C16H28N2O7
Mal-PEG2-Amide
CAS 2639395-35-8C11H16N2O5
Azido-PEG5-maleimide
CAS 2742425-31-4C19H31N5O8
Mal-PEG2-oxyamine
CAS 1146245-73-9C10H16N2O5
Mal-PEG4-Glu(OH)-NH-m-PEG24
CAS 2204309-09-9C72H134N4O35
Mal-PEG4-azide
CAS 2055885-64-6C17H27N5O7
Maleimido-mono-amide-DTPA
CAS 2032239-75-9C20H29N5O11
Mal-amide-PEG2-oxyamine-Boc
CAS 2253965-15-8C18H29N3O8
Mal-amide-PEG2-oxyamine
CAS 2253965-09-0C13H21N3O6
Maleimide-PEG2-hydrazide TFA
CAS 2512213-64-6C16H23F3N4O8
Mal-PEG4-bis-PEG4-propargyl
CAS 2882973-11-5C49H81N5O20
- Mal-PEG3-CH2CH2N32253965-04-5C12H18N4O5
- 1-(20-Amino-3,6,9,12,15,18-hexaoxaicosyl)-1H-pyrrole-2,5-dione2170654-75-6C18H32N2O8
- 21-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-19-oxo-3,6,9,12,15-pentaoxa-18-azahenicosanoic acid151225-46-6C19H30N2O10
- N-(29-Amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide 2,2,2-trifluoroacetate2569576-12-9C29H50F3N3O14
- N-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide 2,2,2-trifluoroacetate1801876-81-2C15H22F3N3O7
- Mal-propionylamido-PEG4-aceticacid1424363-49-4C17H26N2O9
- 1-(38-Amino-3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontyl)-1H-pyrrole-2,5-dione2170654-81-4C30H56N2O14
- Mal-PEG12-NH-Boc2170654-80-3C35H64N2O16
- Mal-Amido-PEG5-alkyne2496687-04-6C20H30N2O8
- 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(15-hydrazinyl-15-oxo-3,6,9,12-tetraoxapentadecyl)propanamide 2,2,2-trifluoroacetate870487-86-8C20H31F3N4O10
- Mal-propionylamido-PEG3-aceticacid450368-58-8C15H22N2O8
- Mal-PEG4-C2-NH2 TFA2512227-13-1C16H25F3N2O8
- Mal-PEG3-CH2 tBu-ester518044-33-2C16H25NO7
- 2-(Dimethylamino)-N-[6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl]acetamide2393406-59-0C14H23N3O3
- (S)-2-Amino-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoic Acid Hydrochloride1467777-26-9C10H15ClN2O4
- 1-(4-Aminobutyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate1639876-58-6C10H13F3N2O4
- 1 suppliersAlkyne maleimide2785323-77-3C12H14N2O3
- 1-[2-(Methylamino)ethyl]-2,5-dihydro-1H-pyrrole-2,5-dione hydrochloride1813589-78-4C7H11ClN2O2
- 1-(20-Hydroxy-3,6,9,12,15,18-hexaoxaicosyl)-3,4-dimethyl-1H-pyrrole-2,5-dione86729-61-5C20H35NO9
- 1-(3,6,9,12,15-Pentaoxaoctadec-17-yn-1-yl)-1H-pyrrole-2,5-dione2514947-01-2C17H25NO7
- N-kappa-Maleimidoundecanoic acid hydrazide trifluoroacetate (1:1)1593661-78-9C17H26F3N3O5
- 1-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione 2,2,2-trifluoroacetate2830214-77-0C14H21F3N2O7
- Ethyl 3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-2,2-dimethylpropanoate2597333-53-2C11H15NO4
- MC-Aaa-nhch2och2cooh2414594-28-6C22H33N5O9
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1cn[nH]c1](/scaffold/WTKZEGDFNFYCGP-UHFFFAOYSA-N/structure.svg)
![Scaffold c1c[nH]cn1](/scaffold/RAXXELZNTBOGNW-UHFFFAOYSA-N/structure.svg)
![Scaffold c1cc[nH]c1](/scaffold/KAESVJOAVNADME-UHFFFAOYSA-N/structure.svg)
![Scaffold c1nc[nH]n1](/scaffold/NSPMIYGKQJPBQR-UHFFFAOYSA-N/structure.svg)
