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Murcko scaffold

Maleimide scaffold

637 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
7
Chemicals
637
With full pages
87
Scaffold SMILES

O=C1C=CC(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Maleimide page
Murcko scaffold O=C1C=CC(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 288 of 637 chemicals

1-(2,2-Dimethoxyethyl)-3,4-dimethylpyrrole-2,5-dione chemical structure, C10H15NO4, CAS 181862-87-3
1-(2,2-Dimethoxyethyl)-3,4-dimethylpyrrole-2,5-dione
CAS 181862-87-3C10H15NO4
2-(3,4-Dimethyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoic acid chemical structure, C10H13NO4, CAS 183149-83-9
2-(3,4-Dimethyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoic acid
CAS 183149-83-9C10H13NO4
1-(1-Hydroxypropan-2-yl)-2,5-dihydro-1H-pyrrole-2,5-dione chemical structure, C7H9NO3, CAS 176429-10-0
1-(1-Hydroxypropan-2-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
CAS 176429-10-0C7H9NO3
1-(2-Aminoethyl)-2,5-dihydro-1H-pyrrole-2,5-dione hydrochloride chemical structure, C6H9ClN2O2, CAS 134272-64-3
1-(2-Aminoethyl)-2,5-dihydro-1H-pyrrole-2,5-dione hydrochloride
CAS 134272-64-3C6H9ClN2O2
1-(3-Hydroxypropyl)-2,5-dihydro-1H-pyrrole-2,5-dione chemical structure, C7H9NO3, CAS 34321-80-7
1-(3-Hydroxypropyl)-2,5-dihydro-1H-pyrrole-2,5-dione
CAS 34321-80-7C7H9NO3
6-Maleimido-1-hexanal chemical structure, C10H13NO3, CAS 1076198-37-2
6-Maleimido-1-hexanal
CAS 1076198-37-2C10H13NO3
1-(3-Aminopropyl)-2,5-dihydro-1H-pyrrole-2,5-dione chemical structure, C7H10N2O2, CAS 110008-25-8
1-(3-Aminopropyl)-2,5-dihydro-1H-pyrrole-2,5-dione
CAS 110008-25-8C7H10N2O2
1-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione chemical structure, C10H16N2O4, CAS 660843-22-1
1-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione
CAS 660843-22-1C10H16N2O4
2-(3-Methyl-2,5-dioxopyrrol-1-yl)propanoic acid chemical structure, C8H9NO4, CAS 144748-80-1
2-(3-Methyl-2,5-dioxopyrrol-1-yl)propanoic acid
CAS 144748-80-1C8H9NO4
2-(3-Methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid chemical structure, C7H7NO4, CAS 10490-20-7
2-(3-Methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetic acid
CAS 10490-20-7C7H7NO4
1-(6-Aminohexyl)-1H-pyrrole-2,5-dione chemical structure, C10H16N2O2, CAS 121663-74-9
1-(6-Aminohexyl)-1H-pyrrole-2,5-dione
CAS 121663-74-9C10H16N2O2
tert-Butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate chemical structure, C15H24N2O4, CAS 124529-64-2
tert-Butyl (6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexyl)carbamate
CAS 124529-64-2C15H24N2O4
1-(6-Aminohexyl)-2,5-dihydro-1H-pyrrole-2,5-dione hydrochloride chemical structure, C10H17ClN2O2, CAS 75238-09-4
1-(6-Aminohexyl)-2,5-dihydro-1H-pyrrole-2,5-dione hydrochloride
CAS 75238-09-4C10H17ClN2O2
(3-Methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl acetate chemical structure, C8H9NO4, CAS 117491-56-2
(3-Methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl acetate
CAS 117491-56-2C8H9NO4
5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid chemical structure, C9H11NO4, CAS 57078-99-6
5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid
CAS 57078-99-6C9H11NO4
(3,4-Dimethyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl acetate chemical structure, C9H11NO4, CAS 117491-57-3
(3,4-Dimethyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl acetate
CAS 117491-57-3C9H11NO4
N-Maleoyl-6-NH2hexanoic acid,ET ester chemical structure, C12H17NO4, CAS 57079-07-9
N-Maleoyl-6-NH2hexanoic acid,ET ester
CAS 57079-07-9C12H17NO4
1-(5-Aminopentyl)-1H-pyrrole-2,5-dione 2,2,2-Trifluoroacetate chemical structure, C11H15F3N2O4, CAS 222159-87-7
1-(5-Aminopentyl)-1H-pyrrole-2,5-dione 2,2,2-Trifluoroacetate
CAS 222159-87-7C11H15F3N2O4
1-(5-Aminopentyl)-2,5-dihydro-1H-pyrrole-2,5-dione hydrochloride chemical structure, C9H15ClN2O2, CAS 510709-83-8
1-(5-Aminopentyl)-2,5-dihydro-1H-pyrrole-2,5-dione hydrochloride
CAS 510709-83-8C9H15ClN2O2
(S)-2-(Boc-amino)-6-(2,5-dioxo-2,5-dihydro-1-pyrrolyl)hexanoic Acid chemical structure, C15H22N2O6
(S)-2-(Boc-amino)-6-(2,5-dioxo-2,5-dihydro-1-pyrrolyl)hexanoic Acid
C15H22N2O6
6-Maleimidohexanehydrazide trifluoroacetate chemical structure, C12H16F3N3O5, CAS 151038-94-7
6-Maleimidohexanehydrazide trifluoroacetate
CAS 151038-94-7C12H16F3N3O5
3-[2-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]propanoic acid chemical structure, C14H20N2O7, CAS 756525-98-1
3-[2-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]propanoic acid
CAS 756525-98-1C14H20N2O7
N-(4-Aminobutyl)maleimide chemical structure, C8H12N2O2, CAS 945530-68-7
N-(4-Aminobutyl)maleimide
CAS 945530-68-7C8H12N2O2
N-Arachidonylmaleimide chemical structure, C24H35NO2, CAS 876305-42-9
N-Arachidonylmaleimide
CAS 876305-42-9C24H35NO2