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Murcko scaffold

Maleimide scaffold

637 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
7
Chemicals
637
With full pages
87
Scaffold SMILES

O=C1C=CC(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Maleimide page
Murcko scaffold O=C1C=CC(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 337 to 384 of 637 chemicals

3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-methoxyethyl)propanamide chemical structure, C10H14N2O4, CAS 1566615-85-7
3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(2-methoxyethyl)propanamide
CAS 1566615-85-7C10H14N2O4
3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(15-hydrazinyl-15-oxo-3,6,9,12-tetraoxapentadecyl)propanamide chemical structure, C18H30N4O8, CAS 870487-43-7
3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(15-hydrazinyl-15-oxo-3,6,9,12-tetraoxapentadecyl)propanamide
CAS 870487-43-7C18H30N4O8
1-(2-(Prop-2-yn-1-yloxy)ethyl)-1H-pyrrole-2,5-dione chemical structure, C9H9NO3, CAS 2167649-06-9
1-(2-(Prop-2-yn-1-yloxy)ethyl)-1H-pyrrole-2,5-dione
CAS 2167649-06-9C9H9NO3
1-[2-(2-Azidoethoxy)ethyl]pyrrole-2,5-dione chemical structure, C8H10N4O3, CAS 3092263-58-3
1-[2-(2-Azidoethoxy)ethyl]pyrrole-2,5-dione
CAS 3092263-58-3C8H10N4O3
1-(4-N-Boc-aminobutyl)-1H-pyrrole-2,5-dione chemical structure, C13H20N2O4, CAS 857074-62-5
1-(4-N-Boc-aminobutyl)-1H-pyrrole-2,5-dione
CAS 857074-62-5C13H20N2O4
N6-(3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl)-L-lysine chemical structure, C13H19N3O5, CAS 1260029-84-2
N6-(3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl)-L-lysine
CAS 1260029-84-2C13H19N3O5
MC-Val-Cit-OH chemical structure, C21H33N5O7, CAS 916746-27-5
MC-Val-Cit-OH
CAS 916746-27-5C21H33N5O7
Mal-PEG6-Acid chemical structure, C19H31NO10, CAS 518044-42-3
Mal-PEG6-Acid
CAS 518044-42-3C19H31NO10
3-Methyl-1-(3,3,3-trifluoropropyl)-2,5-dihydro-1H-pyrrole-2,5-dione chemical structure, C8H8F3NO2, CAS 1341433-56-4
3-Methyl-1-(3,3,3-trifluoropropyl)-2,5-dihydro-1H-pyrrole-2,5-dione
CAS 1341433-56-4C8H8F3NO2
1-[2-(Ethylmethylamino)ethyl]-3-methyl-1H-pyrrole-2,5-dione chemical structure, C10H16N2O2, CAS 1249522-50-6
1-[2-(Ethylmethylamino)ethyl]-3-methyl-1H-pyrrole-2,5-dione
CAS 1249522-50-6C10H16N2O2
1-(3-Aminobutyl)pyrrole-2,5-dione chemical structure, C8H12N2O2, CAS 1339458-40-0
1-(3-Aminobutyl)pyrrole-2,5-dione
CAS 1339458-40-0C8H12N2O2
2-(3,4-Dimethyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanenitrile chemical structure, C11H14N2O2, CAS 1405741-72-1
2-(3,4-Dimethyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanenitrile
CAS 1405741-72-1C11H14N2O2
2-{[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl]sulfanyl}acetic acid chemical structure, C8H9NO4S, CAS 1354714-64-9
2-{[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl]sulfanyl}acetic acid
CAS 1354714-64-9C8H9NO4S
2-[3-(2,5-Dioxopyrrol-1-yl)propoxy]acetic acid chemical structure, C9H11NO5, CAS 1354714-69-4
2-[3-(2,5-Dioxopyrrol-1-yl)propoxy]acetic acid
CAS 1354714-69-4C9H11NO5
2-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)acetic acid chemical structure, C8H9NO5, CAS 1354714-66-1
2-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)acetic acid
CAS 1354714-66-1C8H9NO5
Maleimidocaproyl valine chemical structure, C15H22N2O5, CAS 1263819-22-2
Maleimidocaproyl valine
CAS 1263819-22-2C15H22N2O5
Mal-PEG4-OH chemical structure, C12H19NO6, CAS 1421933-37-0
Mal-PEG4-OH
CAS 1421933-37-0C12H19NO6
Octanoic acid, 8-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]- chemical structure, C15H22N2O5, CAS 862843-30-9
Octanoic acid, 8-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]-
CAS 862843-30-9C15H22N2O5
(2S)-2-[6-(2,5-Dioxopyrrol-1-yl)hexanoylamino]-5-ureido-pentanoic acid chemical structure, C16H24N4O6, CAS 928346-87-6
(2S)-2-[6-(2,5-Dioxopyrrol-1-yl)hexanoylamino]-5-ureido-pentanoic acid
CAS 928346-87-6C16H24N4O6
1-(4-Aminobutyl)-1H-pyrrole-2,5-dione hydrochloride chemical structure, C8H13ClN2O2, CAS 952292-18-1
1-(4-Aminobutyl)-1H-pyrrole-2,5-dione hydrochloride
CAS 952292-18-1C8H13ClN2O2
N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycine chemical structure, C14H19N3O6, CAS 1342820-37-4
N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycylglycine
CAS 1342820-37-4C14H19N3O6
(S)-2-((S)-2-(6-(2,5-Dioxo-2H-pyrrol-1(5H)-yl)hexanamido)-3-methylbutanamido)propanoic acid chemical structure, C18H27N3O6, CAS 1342211-31-7
(S)-2-((S)-2-(6-(2,5-Dioxo-2H-pyrrol-1(5H)-yl)hexanamido)-3-methylbutanamido)propanoic acid
CAS 1342211-31-7C18H27N3O6
1-(Octadec-1-en-1-yl)-1H-pyrrole-2,5-dione chemical structure, C22H37NO2, CAS 112527-21-6
1-(Octadec-1-en-1-yl)-1H-pyrrole-2,5-dione
CAS 112527-21-6C22H37NO2
1-(6-(Aminooxy)hexyl)-1H-pyrrole-2,5-dione chemical structure, C10H16N2O3, CAS 937161-22-3
1-(6-(Aminooxy)hexyl)-1H-pyrrole-2,5-dione
CAS 937161-22-3C10H16N2O3