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Murcko scaffold

Maleimide scaffold

637 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
7
Chemicals
637
With full pages
87
Scaffold SMILES

O=C1C=CC(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Maleimide page
Murcko scaffold O=C1C=CC(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 289 to 336 of 637 chemicals

1-Hydroxy-3,4-dimethoxy-1H-pyrrole-2,5-dione chemical structure, C6H7NO5, CAS 177087-38-6
1-Hydroxy-3,4-dimethoxy-1H-pyrrole-2,5-dione
CAS 177087-38-6C6H7NO5
2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl butyrate chemical structure, C8H9NO4, CAS 479200-80-1
2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl butyrate
CAS 479200-80-1C8H9NO4
(S)-2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)succinic acid chemical structure, C8H7NO6, CAS 346670-61-9
(S)-2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)succinic acid
CAS 346670-61-9C8H7NO6
3-Isopropyl-1-methyl-1H-pyrrole-2,5-dione chemical structure, C8H11NO2, CAS 132162-20-0
3-Isopropyl-1-methyl-1H-pyrrole-2,5-dione
CAS 132162-20-0C8H11NO2
3,4-Dichloro-2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carbothioamide chemical structure, C5H2Cl2N2O2S, CAS 37454-71-0
3,4-Dichloro-2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carbothioamide
CAS 37454-71-0C5H2Cl2N2O2S
3-Amino-4-methyl-1H-pyrrole-2,5-dione chemical structure, C5H6N2O2, CAS 1089921-15-2
3-Amino-4-methyl-1H-pyrrole-2,5-dione
CAS 1089921-15-2C5H6N2O2
2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-2-methylpropanenitrile chemical structure, C8H8N2O2, CAS 1240384-54-6
2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-2-methylpropanenitrile
CAS 1240384-54-6C8H8N2O2
2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetonitrile chemical structure, C6H4N2O2, CAS 1184639-97-1
2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetonitrile
CAS 1184639-97-1C6H4N2O2
3-[2-[2-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido]ethoxy]ethoxy]propanoic Acid chemical structure, C17H26N2O7, CAS 1263044-55-8
3-[2-[2-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido]ethoxy]ethoxy]propanoic Acid
CAS 1263044-55-8C17H26N2O7
19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoic Acid chemical structure, C18H28N2O9, CAS 1263045-16-4
19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoic Acid
CAS 1263045-16-4C18H28N2O9
1-Maleimido-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oyl-(N'-t-butyloxycarbonyl)hydrazid chemical structure, C23H38N4O10, CAS 1127247-28-2
1-Maleimido-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oyl-(N'-t-butyloxycarbonyl)hydrazid
CAS 1127247-28-2C23H38N4O10
Mal-amido-PEG8-acid chemical structure, C26H44N2O13, CAS 1334177-86-4
Mal-amido-PEG8-acid
CAS 1334177-86-4C26H44N2O13
N-(2-Aminoethyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide chemical structure, C9H13N3O3, CAS 820247-10-7
N-(2-Aminoethyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide
CAS 820247-10-7C9H13N3O3
Maleimido-PEG(4)-[PEG(4)-OMe]3 chemical structure, C58H106N6O26, CAS 1333154-72-5
Maleimido-PEG(4)-[PEG(4)-OMe]3
CAS 1333154-72-5C58H106N6O26
N-[2-[2-[2-[2-[3-[[1,3-Bis[3-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethylamino]-3-oxopropoxy]-2-[[3-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethylamino]-3-oxopropoxy]methyl]propan-2-yl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-(2,5-dioxopyrrol-1-yl)propanamide chemical structure, C82H154N6O38, CAS 1334179-89-3
N-[2-[2-[2-[2-[3-[[1,3-Bis[3-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethylamino]-3-oxopropoxy]-2-[[3-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethylamino]-3-oxopropoxy]methyl]propan-2-yl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethyl]-3-(2,5-dioxopyrrol-1-yl)propanamide
CAS 1334179-89-3C82H154N6O38
m-PEG4-Mal chemical structure, C16H26N2O7, CAS 1263044-81-0
m-PEG4-Mal
CAS 1263044-81-0C16H26N2O7
m-PEG8-Mal chemical structure, C24H42N2O11, CAS 1334169-90-2
m-PEG8-Mal
CAS 1334169-90-2C24H42N2O11
4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-sulfobutanoic acid chemical structure, C8H9NO7S, CAS 1193111-52-2
4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-sulfobutanoic acid
CAS 1193111-52-2C8H9NO7S
4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanehydrazide chemical structure, C8H11N3O3, CAS 181148-01-6
4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanehydrazide
CAS 181148-01-6C8H11N3O3
1-Icosa-5,8,11,14-tetraenylpyrrole-2,5-dione chemical structure, C24H35NO2
1-Icosa-5,8,11,14-tetraenylpyrrole-2,5-dione
C24H35NO2
2-[Carboxymethyl-[6-(2,5-dioxopyrrol-1-yl)hexyl]amino]acetic acid, 4-methylbenzenesulfonate chemical structure, C21H27N2O9S-, CAS 445390-54-5
2-[Carboxymethyl-[6-(2,5-dioxopyrrol-1-yl)hexyl]amino]acetic acid, 4-methylbenzenesulfonate
CAS 445390-54-5C21H27N2O9S-
1-[2-(2-Aminoethoxy)ethyl]pyrrole-2,5-dione chemical structure, C8H12N2O3, CAS 131274-16-3
1-[2-(2-Aminoethoxy)ethyl]pyrrole-2,5-dione
CAS 131274-16-3C8H12N2O3
1-(3-Oxobutyl)-2,5-dihydro-1H-pyrrole-2,5-dione chemical structure, C8H9NO3, CAS 1546506-43-7
1-(3-Oxobutyl)-2,5-dihydro-1H-pyrrole-2,5-dione
CAS 1546506-43-7C8H9NO3
1-(114C)ethylpyrrole-2,5-dione chemical structure, C6H7NO2, CAS 62356-37-0
1-(114C)ethylpyrrole-2,5-dione
CAS 62356-37-0C6H7NO2