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Murcko scaffold

Maleimide scaffold

637 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
7
Chemicals
637
With full pages
87
Scaffold SMILES

O=C1C=CC(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the Maleimide page
Murcko scaffold O=C1C=CC(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 385 to 432 of 637 chemicals

3-Chloro-1,4-dimethyl-1H-pyrrole-2,5-dione chemical structure, C6H6ClNO2, CAS 90492-15-2
3-Chloro-1,4-dimethyl-1H-pyrrole-2,5-dione
CAS 90492-15-2C6H6ClNO2
13-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)tridecanoic acid chemical structure, C17H27NO4, CAS 112500-65-9
13-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)tridecanoic acid
CAS 112500-65-9C17H27NO4
Propanoyl chloride--1H-pyrrole-2,5-dione (1/1) chemical structure, C7H8ClNO3, CAS 121215-45-0
Propanoyl chloride--1H-pyrrole-2,5-dione (1/1)
CAS 121215-45-0C7H8ClNO3
1-(2,2,2-Trichloro-1-hydroxyethyl)-1H-pyrrole-2,5-dione chemical structure, C6H4Cl3NO3, CAS 144235-83-6
1-(2,2,2-Trichloro-1-hydroxyethyl)-1H-pyrrole-2,5-dione
CAS 144235-83-6C6H4Cl3NO3
1-[(Iodoacetyl)oxy]-1H-pyrrole-2,5-dione chemical structure, C6H4INO4, CAS 151199-81-4
1-[(Iodoacetyl)oxy]-1H-pyrrole-2,5-dione
CAS 151199-81-4C6H4INO4
Prop-2-en-1-yl (2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetate chemical structure, C9H9NO4, CAS 195319-43-8
Prop-2-en-1-yl (2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetate
CAS 195319-43-8C9H9NO4
1-(But-3-en-1-yl)-3,4-dimethyl-1H-pyrrole-2,5-dione chemical structure, C10H13NO2, CAS 651043-86-6
1-(But-3-en-1-yl)-3,4-dimethyl-1H-pyrrole-2,5-dione
CAS 651043-86-6C10H13NO2
1H-Pyrrole-2,5-dione, 1-[(diethylamino)methyl]- chemical structure, C9H14N2O2, CAS 64432-31-1
1H-Pyrrole-2,5-dione, 1-[(diethylamino)methyl]-
CAS 64432-31-1C9H14N2O2
3,4-Bis(hydroxymethyl)-1-methyl-1H-pyrrole-2,5-dione chemical structure, C7H9NO4, CAS 61892-71-5
3,4-Bis(hydroxymethyl)-1-methyl-1H-pyrrole-2,5-dione
CAS 61892-71-5C7H9NO4
(2S)-2-[3-(2,5-Dioxopyrrol-1-yl)propanoylamino]-4-methylpentanoic acid chemical structure, C13H18N2O5, CAS 88499-28-9
(2S)-2-[3-(2,5-Dioxopyrrol-1-yl)propanoylamino]-4-methylpentanoic acid
CAS 88499-28-9C13H18N2O5
3,4-Dibromo-1-pentyl-1H-pyrrole-2,5-dione chemical structure, C9H11Br2NO2, CAS 88340-15-2
3,4-Dibromo-1-pentyl-1H-pyrrole-2,5-dione
CAS 88340-15-2C9H11Br2NO2
N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycine chemical structure, C12H16N2O5, CAS 854021-64-0
N-[6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoyl]glycine
CAS 854021-64-0C12H16N2O5
6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(prop-2-yn-1-yl)hexanamide chemical structure, C13H16N2O3, CAS 920749-05-9
6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-(prop-2-yn-1-yl)hexanamide
CAS 920749-05-9C13H16N2O3
1-(12-Sulfanyldodecyl)-1H-pyrrole-2,5-dione chemical structure, C16H27NO2S, CAS 915798-83-3
1-(12-Sulfanyldodecyl)-1H-pyrrole-2,5-dione
CAS 915798-83-3C16H27NO2S
Mal-PEG4-Propargyl chemical structure, C15H21NO6, CAS 1262681-30-0
Mal-PEG4-Propargyl
CAS 1262681-30-0C15H21NO6
1-(3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yn-1-yl)-1H-pyrrole-2,5-dione chemical structure, C23H37NO10, CAS 1422540-97-3
1-(3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yn-1-yl)-1H-pyrrole-2,5-dione
CAS 1422540-97-3C23H37NO10
3-Maleimidopropiohydrazide trifluoroacetate chemical structure, C9H10F3N3O5, CAS 359436-61-6
3-Maleimidopropiohydrazide trifluoroacetate
CAS 359436-61-6C9H10F3N3O5
5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanehydrazide chemical structure, C9H13N3O3, CAS 1286754-17-3
5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanehydrazide
CAS 1286754-17-3C9H13N3O3
1H-Pyrrole-1-propanoic acid, 2,5-dihydro-3-(1-methylethyl)-2,5-dioxo-, (3E)-4-carboxy-3-methyl-3-buten-1-yl ester chemical structure, C16H21NO6, CAS 1414774-74-5
1H-Pyrrole-1-propanoic acid, 2,5-dihydro-3-(1-methylethyl)-2,5-dioxo-, (3E)-4-carboxy-3-methyl-3-buten-1-yl ester
CAS 1414774-74-5C16H21NO6
Methyl 3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate chemical structure, C6H3Br2NO4, CAS 1442447-48-4
Methyl 3,4-dibromo-2,5-dioxo-2,5-dihydro-1H-pyrrole-1-carboxylate
CAS 1442447-48-4C6H3Br2NO4
3,4-Dibromo-1-(prop-2-yn-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione chemical structure, C7H3Br2NO2, CAS 1356012-81-1
3,4-Dibromo-1-(prop-2-yn-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
CAS 1356012-81-1C7H3Br2NO2
4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanehydrazide hydrochloride chemical structure, C8H12ClN3O3, CAS 1588441-05-7
4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanehydrazide hydrochloride
CAS 1588441-05-7C8H12ClN3O3
2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetohydrazide 2,2,2-trifluoroacetate chemical structure, C8H8F3N3O5, CAS 1391054-27-5
2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetohydrazide 2,2,2-trifluoroacetate
CAS 1391054-27-5C8H8F3N3O5
1-(17-Hydroxy-3,6,9,12,15-pentaoxaheptadecyl)-1H-pyrrole-2,5-dione chemical structure, C16H27NO8, CAS 1584544-42-2
1-(17-Hydroxy-3,6,9,12,15-pentaoxaheptadecyl)-1H-pyrrole-2,5-dione
CAS 1584544-42-2C16H27NO8