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Murcko scaffold

Ring system with 4 rings and 25 atoms

20 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 25
Chemicals: 20
With full pages: 13

Scaffold SMILES

O=c1cc(CN2CCN(Cc3ccccc3)CC2)c2ccccc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1cc(CN2CCN(Cc3ccccc3)CC2)c2ccccc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

4-((4-Benzylpiperazin-1-yl)methyl)-6-chloro-2H-chromen-2-one chemical structure, C21H21ClN2O2, CAS 896834-32-5

4-((4-Benzylpiperazin-1-yl)methyl)-6-chloro-2H-chromen-2-one

CAS 896834-32-5C₂₁H₂₁ClN₂O₂

4-[(4-Benzylpiperazin-1-yl)methyl]-7-methyl-2H-chromen-2-one chemical structure, C22H24N2O2, CAS 847162-39-4

4-[(4-Benzylpiperazin-1-yl)methyl]-7-methyl-2H-chromen-2-one

CAS 847162-39-4C₂₂H₂₄N₂O₂

4-[(4-Benzylpiperazin-1-yl)methyl]-6-hydroxy-7-methyl-2H-chromen-2-one chemical structure, C22H24N2O3, CAS 859112-12-2

4-[(4-Benzylpiperazin-1-yl)methyl]-6-hydroxy-7-methyl-2H-chromen-2-one

CAS 859112-12-2C₂₂H₂₄N₂O₃

4-[(4-Benzylpiperazin-1-yl)methyl]-6-hydroxychromen-2-one chemical structure, C21H22N2O3, CAS 859110-63-7

4-[(4-Benzylpiperazin-1-yl)methyl]-6-hydroxychromen-2-one

CAS 859110-63-7C₂₁H₂₂N₂O₃

4-[(4-Benzylpiperazin-1-yl)methyl]-6-methylchromen-2-one chemical structure, C22H24N2O2, CAS 850193-94-1

4-[(4-Benzylpiperazin-1-yl)methyl]-6-methylchromen-2-one

CAS 850193-94-1C₂₂H₂₄N₂O₂

4-((4-Benzylpiperazin-1-yl)methyl)-6,7-dimethyl-2H-chromen-2-one chemical structure, C23H26N2O2, CAS 782465-05-8

4-((4-Benzylpiperazin-1-yl)methyl)-6,7-dimethyl-2H-chromen-2-one

CAS 782465-05-8C₂₃H₂₆N₂O₂

4-((4-Benzylpiperazin-1-yl)methyl)-6-isopropyl-2H-chromen-2-one chemical structure, C24H28N2O2, CAS 850241-02-0

4-((4-Benzylpiperazin-1-yl)methyl)-6-isopropyl-2H-chromen-2-one

CAS 850241-02-0C₂₄H₂₈N₂O₂

4-((4-Benzylpiperazin-1-yl)methyl)-6-chloro-7-methyl-2H-chromen-2-one chemical structure, C22H23ClN2O2, CAS 782464-93-1

4-((4-Benzylpiperazin-1-yl)methyl)-6-chloro-7-methyl-2H-chromen-2-one

CAS 782464-93-1C₂₂H₂₃ClN₂O₂

4-[(4-Benzylpiperazin-1-yl)methyl]-7,8-dimethylchromen-2-one chemical structure, C23H26N2O2, CAS 784167-11-9

4-[(4-Benzylpiperazin-1-yl)methyl]-7,8-dimethylchromen-2-one

CAS 784167-11-9C₂₃H₂₆N₂O₂

4-[(4-Benzylpiperazin-1-yl)methyl]-6-tert-butyl-2H-chromen-2-one chemical structure, C25H30N2O2, CAS 862210-73-9

4-[(4-Benzylpiperazin-1-yl)methyl]-6-tert-butyl-2H-chromen-2-one

CAS 862210-73-9C₂₅H₃₀N₂O₂

4-[(4-Benzylpiperazin-1-yl)methyl]-5,7,8-trimethyl-2H-chromen-2-one chemical structure, C24H28N2O2, CAS 862243-79-6

4-[(4-Benzylpiperazin-1-yl)methyl]-5,7,8-trimethyl-2H-chromen-2-one

CAS 862243-79-6C₂₄H₂₈N₂O₂

4-[(4-Benzylpiperazin-1-yl)methyl]-6,8-dimethyl-2H-chromen-2-one chemical structure, C23H26N2O2, CAS 877795-70-5

4-[(4-Benzylpiperazin-1-yl)methyl]-6,8-dimethyl-2H-chromen-2-one

CAS 877795-70-5C₂₃H₂₆N₂O₂

4-[(4-Benzylpiperazin-1-yl)methyl]-7-hydroxy-8-methyl-2H-chromen-2-one chemical structure, C22H24N2O3, CAS 847932-19-8

4-[(4-Benzylpiperazin-1-yl)methyl]-7-hydroxy-8-methyl-2H-chromen-2-one

CAS 847932-19-8C₂₂H₂₄N₂O₃

4-((4-Benzylpiperazin-1-yl)methyl)-7,8-dihydroxy-2H-chromen-2-one chemical structure, C21H22N2O4, CAS 859110-91-1

4-((4-Benzylpiperazin-1-yl)methyl)-7,8-dihydroxy-2H-chromen-2-one

CAS 859110-91-1C₂₁H₂₂N₂O₄

4-((4-Benzylpiperazin-1-yl)methyl)-5-hydroxy-7-methyl-2H-chromen-2-one chemical structure, C22H24N2O3, CAS 896597-02-7

4-((4-Benzylpiperazin-1-yl)methyl)-5-hydroxy-7-methyl-2H-chromen-2-one

CAS 896597-02-7C₂₂H₂₄N₂O₃

4-((4-Benzylpiperazin-1-yl)methyl)-5,7,8-trimethyl-2H-chromen-2-one dihydrochloride chemical structure, C24H30Cl2N2O2, CAS 1215550-40-5

4-((4-Benzylpiperazin-1-yl)methyl)-5,7,8-trimethyl-2H-chromen-2-one dihydrochloride

CAS 1215550-40-5C₂₄H₃₀Cl₂N₂O₂

4-[(4-Benzylpiperazin-1-yl)methyl]-6-chloro-5,7-dimethyl-2H-chromen-2-one dihydrochloride chemical structure, C23H27Cl3N2O2, CAS 1177994-49-8

4-[(4-Benzylpiperazin-1-yl)methyl]-6-chloro-5,7-dimethyl-2H-chromen-2-one dihydrochloride

CAS 1177994-49-8C₂₃H₂₇Cl₃N₂O₂

4-((4-Benzylpiperazin-1-yl)methyl)-7-methoxy-2H-chromen-2-one dihydrochloride chemical structure, C22H26Cl2N2O3, CAS 176961-62-9

4-((4-Benzylpiperazin-1-yl)methyl)-7-methoxy-2H-chromen-2-one dihydrochloride

CAS 176961-62-9C₂₂H₂₆Cl₂N₂O₃

4-((4-Benzylpiperazin-1-yl)methyl)-5,7-dimethyl-2H-chromen-2-one dihydrochloride chemical structure, C23H28Cl2N2O2, CAS 1216878-46-4

4-((4-Benzylpiperazin-1-yl)methyl)-5,7-dimethyl-2H-chromen-2-one dihydrochloride

CAS 1216878-46-4C₂₃H₂₈Cl₂N₂O₂

4-[(4-Benzylpiperazin-1-yl)methyl]-6-ethyl-7-hydroxy-2H-chromen-2-one dihydrochloride chemical structure, C23H28Cl2N2O3, CAS 1177891-06-3

4-[(4-Benzylpiperazin-1-yl)methyl]-6-ethyl-7-hydroxy-2H-chromen-2-one dihydrochloride

CAS 1177891-06-3C₂₃H₂₈Cl₂N₂O₃