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Murcko scaffold

Ring system with 3 rings and 19 atoms

277 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
277
With full pages
16
Scaffold SMILES

O=C(Cn1ccc2ccccc21)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cn1ccc2ccccc21)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 241 to 277 of 277 chemicals

1-{2-[(2-Carboxyphenyl)amino]-2-oxoethyl}-1H-indole-2-carboxylic acid chemical structure, C18H14N2O5, CAS 1242928-26-2
1-{2-[(2-Carboxyphenyl)amino]-2-oxoethyl}-1H-indole-2-carboxylic acid
CAS 1242928-26-2C18H14N2O5
N-(5-Chloro-2-methoxyphenyl)-2-(4-methoxy-1H-indol-1-yl)acetamide chemical structure, C18H17ClN2O3, CAS 1282113-71-6
N-(5-Chloro-2-methoxyphenyl)-2-(4-methoxy-1H-indol-1-yl)acetamide
CAS 1282113-71-6C18H17ClN2O3
N-[3-(Acetylamino)phenyl]-2-(4-methyl-1H-indol-1-yl)acetamide chemical structure, C19H19N3O2, CAS 1282096-83-6
N-[3-(Acetylamino)phenyl]-2-(4-methyl-1H-indol-1-yl)acetamide
CAS 1282096-83-6C19H19N3O2
2-(4-Methoxy-1H-indol-1-yl)-N-[3-(methylsulfanyl)phenyl]acetamide chemical structure, C18H18N2O2S, CAS 1282131-60-5
2-(4-Methoxy-1H-indol-1-yl)-N-[3-(methylsulfanyl)phenyl]acetamide
CAS 1282131-60-5C18H18N2O2S
2-(4-Methoxy-1H-indol-1-yl)-N-(2-methoxyphenyl)acetamide chemical structure, C18H18N2O3, CAS 1282141-94-9
2-(4-Methoxy-1H-indol-1-yl)-N-(2-methoxyphenyl)acetamide
CAS 1282141-94-9C18H18N2O3
2-(5-Bromo-1H-indol-1-yl)-N-(2,6-difluorophenyl)acetamide chemical structure, C16H11BrF2N2O, CAS 1324097-84-8
2-(5-Bromo-1H-indol-1-yl)-N-(2,6-difluorophenyl)acetamide
CAS 1324097-84-8C16H11BrF2N2O
1-{2-[(2-Hydroxyphenyl)amino]-2-oxo ethyl}-1H-indole-7-carboxylic acid chemical structure, C17H14N2O4, CAS 1196047-40-1
1-{2-[(2-Hydroxyphenyl)amino]-2-oxo ethyl}-1H-indole-7-carboxylic acid
CAS 1196047-40-1C17H14N2O4
(2R)-2-tert-Butoxycarbonylamino-3-[4-(2-indol-1-yl-acetylamino)-benzylsulfanyl]-propionic Acid chemical structure, C25H29N3O5S, CAS 796071-91-5
(2R)-2-tert-Butoxycarbonylamino-3-[4-(2-indol-1-yl-acetylamino)-benzylsulfanyl]-propionic Acid
CAS 796071-91-5C25H29N3O5S
2-(3-Acetyl-1H-indol-1-yl)-N-(3-(methylthio)phenyl)acetamide chemical structure, C19H18N2O2S, CAS 1421456-72-5
2-(3-Acetyl-1H-indol-1-yl)-N-(3-(methylthio)phenyl)acetamide
CAS 1421456-72-5C19H18N2O2S
2-(3-Acetyl-1H-indol-1-yl)-N-(2-chloro-6-methylphenyl)acetamide chemical structure, C19H17ClN2O2, CAS 1421500-18-6
2-(3-Acetyl-1H-indol-1-yl)-N-(2-chloro-6-methylphenyl)acetamide
CAS 1421500-18-6C19H17ClN2O2
2-[4-(Acetylamino)-1H-indol-1-yl]-N-(2-chlorophenyl)acetamide chemical structure, C18H16ClN3O2, CAS 1574411-47-4
2-[4-(Acetylamino)-1H-indol-1-yl]-N-(2-chlorophenyl)acetamide
CAS 1574411-47-4C18H16ClN3O2
2-[4-(Acetylamino)-1H-indol-1-yl]-N-phenylacetamide chemical structure, C18H17N3O2, CAS 1574465-94-3
2-[4-(Acetylamino)-1H-indol-1-yl]-N-phenylacetamide
CAS 1574465-94-3C18H17N3O2
Ethyl 4-({[4-(acetylamino)-1H-indol-1-yl]acetyl}amino)benzoate chemical structure, C21H21N3O4, CAS 1574405-04-1
Ethyl 4-({[4-(acetylamino)-1H-indol-1-yl]acetyl}amino)benzoate
CAS 1574405-04-1C21H21N3O4
4-({[4-(Acetylamino)-1H-indol-1-yl]acetyl}amino)benzamide chemical structure, C19H18N4O3, CAS 1574337-41-9
4-({[4-(Acetylamino)-1H-indol-1-yl]acetyl}amino)benzamide
CAS 1574337-41-9C19H18N4O3
2-[4-(Acetylamino)-1H-indol-1-yl]-N-[3-(acetylamino)phenyl]acetamide chemical structure, C20H20N4O3, CAS 1574310-02-3
2-[4-(Acetylamino)-1H-indol-1-yl]-N-[3-(acetylamino)phenyl]acetamide
CAS 1574310-02-3C20H20N4O3
2-[4-(Acetylamino)-1H-indol-1-yl]-N-(2-methoxyphenyl)acetamide chemical structure, C19H19N3O3, CAS 1574336-57-4
2-[4-(Acetylamino)-1H-indol-1-yl]-N-(2-methoxyphenyl)acetamide
CAS 1574336-57-4C19H19N3O3
2-[4-(Acetylamino)-1H-indol-1-yl]-N-(2,5-dimethoxyphenyl)acetamide chemical structure, C20H21N3O4, CAS 1574319-00-8
2-[4-(Acetylamino)-1H-indol-1-yl]-N-(2,5-dimethoxyphenyl)acetamide
CAS 1574319-00-8C20H21N3O4
2-[4-(Acetylamino)-1H-indol-1-yl]-N-(3,4,5-trimethoxyphenyl)acetamide chemical structure, C21H23N3O5, CAS 1574405-44-9
2-[4-(Acetylamino)-1H-indol-1-yl]-N-(3,4,5-trimethoxyphenyl)acetamide
CAS 1574405-44-9C21H23N3O5
2-[4-(Acetylamino)-1H-indol-1-yl]-N-(3-bromophenyl)acetamide chemical structure, C18H16BrN3O2, CAS 1574411-27-0
2-[4-(Acetylamino)-1H-indol-1-yl]-N-(3-bromophenyl)acetamide
CAS 1574411-27-0C18H16BrN3O2
2-[4-(Acetylamino)-1H-indol-1-yl]-N-[5-(acetylamino)-2-methoxyphenyl]acetamide chemical structure, C21H22N4O4, CAS 1574516-30-5
2-[4-(Acetylamino)-1H-indol-1-yl]-N-[5-(acetylamino)-2-methoxyphenyl]acetamide
CAS 1574516-30-5C21H22N4O4
Methyl 4-({[4-(acetylamino)-1H-indol-1-yl]acetyl}amino)benzoate chemical structure, C20H19N3O4, CAS 1574376-74-1
Methyl 4-({[4-(acetylamino)-1H-indol-1-yl]acetyl}amino)benzoate
CAS 1574376-74-1C20H19N3O4
2-[4-(Acetylamino)-1H-indol-1-yl]-N-(3-chlorophenyl)acetamide chemical structure, C18H16ClN3O2, CAS 1574324-66-5
2-[4-(Acetylamino)-1H-indol-1-yl]-N-(3-chlorophenyl)acetamide
CAS 1574324-66-5C18H16ClN3O2
2-[4-(Acetylamino)-1H-indol-1-yl]-N-[3-(methylsulfanyl)phenyl]acetamide chemical structure, C19H19N3O2S, CAS 1574325-40-8
2-[4-(Acetylamino)-1H-indol-1-yl]-N-[3-(methylsulfanyl)phenyl]acetamide
CAS 1574325-40-8C19H19N3O2S
2-[4-(Acetylamino)-1H-indol-1-yl]-N-[4-(propan-2-yl)phenyl]acetamide chemical structure, C21H23N3O2, CAS 1574409-81-6
2-[4-(Acetylamino)-1H-indol-1-yl]-N-[4-(propan-2-yl)phenyl]acetamide
CAS 1574409-81-6C21H23N3O2