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Murcko scaffold

1-{[4-(Thiophen-3-yl)phenyl]methyl}-1H-imidazole scaffold

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
6
With full pages
0
Scaffold SMILES

c1cn(Cc2ccc(-c3ccsc3)cc2)cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-{[4-(Thiophen-3-yl)phenyl]methyl}-1H-imidazole page
Murcko scaffold c1cn(Cc2ccc(-c3ccsc3)cc2)cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

Buloxibutid chemical structure, C23H29N3O4S2, CAS 477775-14-7
Buloxibutid
CAS 477775-14-7C23H29N3O4S2
N-iso-Butyloxycarbonyl-3-(4-imidazol-1-ylmethylphenyl)-5-iso-butylthiophene-2-sulfonamide chemical structure, C23H29N3O4S2, CAS 477775-15-8
N-iso-Butyloxycarbonyl-3-(4-imidazol-1-ylmethylphenyl)-5-iso-butylthiophene-2-sulfonamide
CAS 477775-15-8C23H29N3O4S2
3-(4-Imidazol-1-ylmethylphenyl)-5-iso-butyl-N-tert-butylthiophene-2-sulfonamide chemical structure, C22H29N3O2S2, CAS 477775-35-2
3-(4-Imidazol-1-ylmethylphenyl)-5-iso-butyl-N-tert-butylthiophene-2-sulfonamide
CAS 477775-35-2C22H29N3O2S2
1-{[4-(Thiophen-3-yl)phenyl]methyl}-1H-imidazole chemical structure, C14H12N2S, CAS 160461-96-1
1-{[4-(Thiophen-3-yl)phenyl]methyl}-1H-imidazole
CAS 160461-96-1C14H12N2S
3-(4-((1H-Imidazol-1-yl)methyl)phenyl)-N-(tert-butyl)thiophene-2-sulfonamide chemical structure, C18H21N3O2S2, CAS 2089650-46-2
3-(4-((1H-Imidazol-1-yl)methyl)phenyl)-N-(tert-butyl)thiophene-2-sulfonamide
CAS 2089650-46-2C18H21N3O2S2
Butyl (3-(4-((1H-imidazol-1-yl)methyl)phenyl)-5-isobutylthiophen-2-yl)sulfonylcarbamate sodium salt chemical structure, C23H28N3NaO4S2, CAS 2709031-33-2
Butyl (3-(4-((1H-imidazol-1-yl)methyl)phenyl)-5-isobutylthiophen-2-yl)sulfonylcarbamate sodium salt
CAS 2709031-33-2C23H28N3NaO4S2