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Murcko scaffold

3-Phenylpyrrolidine scaffold

4,373 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
4,373
With full pages
8
Scaffold SMILES

c1ccc(C2CCNC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylpyrrolidine page
Murcko scaffold c1ccc(C2CCNC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,201 to 1,248 of 4,373 chemicals

4-(2,4-Difluorophenyl)-1-ethylpyrrolidine-3-carboxylic acid chemical structure, C13H15F2NO2, CAS 2172154-23-1
4-(2,4-Difluorophenyl)-1-ethylpyrrolidine-3-carboxylic acid
CAS 2172154-23-1C13H15F2NO2
tert-Butyl 3-hydroxy-3-[2-(hydroxymethyl)phenyl]pyrrolidine-1-carboxylate chemical structure, C16H23NO4, CAS 1047656-19-8
tert-Butyl 3-hydroxy-3-[2-(hydroxymethyl)phenyl]pyrrolidine-1-carboxylate
CAS 1047656-19-8C16H23NO4
5-Methyl-3-(2-methylphenyl)pyrrolidin-3-ol chemical structure, C12H17NO, CAS 1003562-08-0
5-Methyl-3-(2-methylphenyl)pyrrolidin-3-ol
CAS 1003562-08-0C12H17NO
2-(3-Pyrrolidinyl)benzamide chemical structure, C11H14N2O, CAS 1260794-36-2
2-(3-Pyrrolidinyl)benzamide
CAS 1260794-36-2C11H14N2O
tert-Butyl 3-(4-bromophenyl)-3-hydroxypyrrolidine-1-carboxylate chemical structure, C15H20BrNO3, CAS 1075189-81-9
tert-Butyl 3-(4-bromophenyl)-3-hydroxypyrrolidine-1-carboxylate
CAS 1075189-81-9C15H20BrNO3
1-[(tert-Butoxy)carbonyl]-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylic acid chemical structure, C16H19F2NO4, CAS 1366836-12-5
1-[(tert-Butoxy)carbonyl]-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylic acid
CAS 1366836-12-5C16H19F2NO4
tert-Butyl 3-hydroxy-4-phenylpyrrolidine-1-carboxylate chemical structure, C15H21NO3, CAS 1628546-55-3
tert-Butyl 3-hydroxy-4-phenylpyrrolidine-1-carboxylate
CAS 1628546-55-3C15H21NO3
tert-Butyl 3-(4-fluorophenyl)-4-hydroxypyrrolidine-1-carboxylate chemical structure, C15H20FNO3, CAS 1824404-92-3
tert-Butyl 3-(4-fluorophenyl)-4-hydroxypyrrolidine-1-carboxylate
CAS 1824404-92-3C15H20FNO3
3-Phenylpyrrolidine-3-carboxylic acid chemical structure, C11H13NO2, CAS 933684-15-2
3-Phenylpyrrolidine-3-carboxylic acid
CAS 933684-15-2C11H13NO2
1-(tert-Butyl) 3-methyl 4-(4-fluorophenyl)pyrrolidine-1,3-dicarboxylate chemical structure, C17H22FNO4, CAS 1823459-33-1
1-(tert-Butyl) 3-methyl 4-(4-fluorophenyl)pyrrolidine-1,3-dicarboxylate
CAS 1823459-33-1C17H22FNO4
tert-Butyl 3-(2-chlorophenyl)-4-(hydroxymethyl)pyrrolidine-1-carboxylate chemical structure, C16H22ClNO3, CAS 1785761-81-0
tert-Butyl 3-(2-chlorophenyl)-4-(hydroxymethyl)pyrrolidine-1-carboxylate
CAS 1785761-81-0C16H22ClNO3
Methyl 2-(3-(pyrrolidin-3-yl)phenyl)acetate chemical structure, C13H17NO2, CAS 960305-39-9
Methyl 2-(3-(pyrrolidin-3-yl)phenyl)acetate
CAS 960305-39-9C13H17NO2
1-tert-Butyl 3-methyl (3R,4S)-4-(3,4-dichlorophenyl)pyrrolidine-1,3-dicarboxylate chemical structure, C17H21Cl2NO4, CAS 1160260-92-3
1-tert-Butyl 3-methyl (3R,4S)-4-(3,4-dichlorophenyl)pyrrolidine-1,3-dicarboxylate
CAS 1160260-92-3C17H21Cl2NO4
4-(3,4-Dichlorophenyl)pyrrolidine-3-carboxylic acid chemical structure, C11H11Cl2NO2, CAS 2166700-42-9
4-(3,4-Dichlorophenyl)pyrrolidine-3-carboxylic acid
CAS 2166700-42-9C11H11Cl2NO2
tert-Butyl (3S,4R)-3-(hydroxymethyl)-4-phenylpyrrolidine-1-carboxylate chemical structure, C16H23NO3, CAS 2173052-88-3
tert-Butyl (3S,4R)-3-(hydroxymethyl)-4-phenylpyrrolidine-1-carboxylate
CAS 2173052-88-3C16H23NO3
Rac-(cis)-tert-butyl-2-(hydroxymethyl)-3-phenylpyrrolidine-1-carboxylate chemical structure, C16H23NO3, CAS 1542241-95-1
Rac-(cis)-tert-butyl-2-(hydroxymethyl)-3-phenylpyrrolidine-1-carboxylate
CAS 1542241-95-1C16H23NO3
3-(Pyrrolidin-3-yl)aniline chemical structure, C10H14N2, CAS 1203796-62-6
3-(Pyrrolidin-3-yl)aniline
CAS 1203796-62-6C10H14N2
(3R,4S)-rel-1-(tert-Butoxycarbonyl)-4-(2-(ethoxycarbonyl)phenyl)pyrrolidine-3-carboxylic acid chemical structure, C19H25NO6, CAS 873846-06-1
(3R,4S)-rel-1-(tert-Butoxycarbonyl)-4-(2-(ethoxycarbonyl)phenyl)pyrrolidine-3-carboxylic acid
CAS 873846-06-1C19H25NO6
(3R,4S)-4-(2-Ethoxycarbonylphenyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acid chemical structure, C19H25NO6
(3R,4S)-4-(2-Ethoxycarbonylphenyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acid
C19H25NO6
tert-Butyl (3-phenylpyrrolidin-3-yl)methylcarbamate chemical structure, C16H24N2O2, CAS 351369-05-6
tert-Butyl (3-phenylpyrrolidin-3-yl)methylcarbamate
CAS 351369-05-6C16H24N2O2
3-Chloro-5-(3-pyrrolidinyl)benzoic acid ethyl ester chemical structure, C13H16ClNO2, CAS 1095274-84-2
3-Chloro-5-(3-pyrrolidinyl)benzoic acid ethyl ester
CAS 1095274-84-2C13H16ClNO2
1-(tert-Butyl)-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylic acid hcl chemical structure, C15H20ClF2NO2, CAS 1956335-80-0
1-(tert-Butyl)-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylic acid hcl
CAS 1956335-80-0C15H20ClF2NO2
4-(4-Bromophenyl)-1-methylpyrrolidin-3-amine chemical structure, C11H15BrN2, CAS 1823415-14-0
4-(4-Bromophenyl)-1-methylpyrrolidin-3-amine
CAS 1823415-14-0C11H15BrN2
3-(4-Bromophenyl)-1-methyl-4-nitropyrrolidine chemical structure, C11H13BrN2O2, CAS 2167355-02-2
3-(4-Bromophenyl)-1-methyl-4-nitropyrrolidine
CAS 2167355-02-2C11H13BrN2O2