Murcko scaffold
3-Phenylpyrrolidine scaffold
4,373 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 4,373
- With full pages
- 197
Scaffold SMILES
c1ccc(C2CCNC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1,873 to 1,920 of 4,373 chemicals
Methyl 3-phenylpyrrolidine-3-carboxylate hydrochloride
CAS 1417546-06-5C12H16ClNO2
![3-Fluoro-3-[3-(trifluoromethyl)phenyl]pyrrolidine hydrochloride chemical structure, C11H12ClF4N, CAS 1803600-36-3](/s/UYUZPICXGSZBGG-UHFFFAOYSA-N.svg)
3-Fluoro-3-[3-(trifluoromethyl)phenyl]pyrrolidine hydrochloride
CAS 1803600-36-3C11H12ClF4N
4-(4-Fluoro-3-methylphenyl)-1-methylpyrrolidine-3-carboxylic acid
CAS 1485115-96-5C13H16FNO2
2,2,2-Trifluoro-N-(4-phenylpyrrolidin-3-yl)acetamide
CAS 1424941-18-3C12H13F3N2O
3-(3,5-Dimethoxyphenyl)-3-fluoropyrrolidine
CAS 1564532-43-9C12H16FNO2
![3-Fluoro-3-[2-(trifluoromethyl)phenyl]pyrrolidine chemical structure, C11H11F4N, CAS 1565649-13-9](/s/NVRDZSXOWBHFAS-UHFFFAOYSA-N.svg)
3-Fluoro-3-[2-(trifluoromethyl)phenyl]pyrrolidine
CAS 1565649-13-9C11H11F4N
3-(2-Chlorophenyl)-3-fluoropyrrolidine
CAS 1566812-83-6C10H11ClFN
3-(3,5-Dimethylphenyl)-3-fluoropyrrolidine
CAS 1564653-82-2C12H16FN
3-(3-Ethylphenyl)-3-fluoropyrrolidine
CAS 1564817-24-8C12H16FN
3-Fluoro-3-(3-fluoro-5-methylphenyl)pyrrolidine
CAS 1565909-48-9C11H13F2N
3-Phenylpyrrolidine-1-sulfonamide
CAS 1774950-90-1C10H14N2O2S
3-Fluoro-3-(3-fluoro-5-methylphenyl)pyrrolidine hydrochloride
CAS 1803600-62-5C11H14ClF2N
3-(3-Ethylphenyl)-3-fluoropyrrolidine hydrochloride
CAS 1803561-48-9C12H17ClFN
3-(2-Chlorophenyl)-3-fluoropyrrolidine hydrochloride
CAS 1803600-84-1C10H12Cl2FN
3-(4-Ethylphenyl)-3-fluoropyrrolidine hydrochloride
CAS 1803603-46-4C12H17ClFN
3-Fluoro-3-(3-methoxyphenyl)pyrrolidine hydrochloride
CAS 1803582-10-6C11H15ClFNO
3-(3,5-Dimethoxyphenyl)-3-fluoropyrrolidine hydrochloride
CAS 1803604-39-8C12H17ClFNO2
![2,2,2-Trifluoro-N-[(3S,4R)-4-phenylpyrrolidin-3-yl]acetamide chemical structure, C12H13F3N2O, CAS 1807920-01-9](/s/YFHIIRBVIAFCMB-VHSXEESVSA-N.svg)
2,2,2-Trifluoro-N-[(3S,4R)-4-phenylpyrrolidin-3-yl]acetamide
CAS 1807920-01-9C12H13F3N2O
3-Fluoro-3-(3-methylphenyl)pyrrolidine hydrochloride
CAS 1803611-13-3C11H15ClFN
3-(3,5-Difluorophenyl)-3-fluoropyrrolidine hydrochloride
CAS 1803583-15-4C10H11ClF3N
Methyl 4-(2,3-dimethoxyphenyl)pyrrolidine-3-carboxylate
CAS 1774303-96-6C14H19NO4
Ethyl 4-(4-fluoro-2-methylphenyl)pyrrolidine-3-carboxylate
CAS 1772885-45-6C14H18FNO2
Ethyl 4-(2,6-difluorophenyl)pyrrolidine-3-carboxylate
CAS 1777615-99-2C13H15F2NO2
![Ethyl 4-[4-(propan-2-yl)phenyl]pyrrolidine-3-carboxylate chemical structure, C16H23NO2, CAS 1712551-74-0](/s/ZYXURYKQHDWWAG-UHFFFAOYSA-N.svg)
Ethyl 4-[4-(propan-2-yl)phenyl]pyrrolidine-3-carboxylate
CAS 1712551-74-0C16H23NO2
- Ethyl 4-(2,5-dimethylphenyl)pyrrolidine-3-carboxylate1772885-72-9C15H21NO2
- Ethyl 4-(2-ethoxyphenyl)pyrrolidine-3-carboxylate1712331-02-6C15H21NO3
- Ethyl 4-(4-fluoro-3-methylphenyl)pyrrolidine-3-carboxylate1772885-98-9C14H18FNO2
- Ethyl 4-(3,4-difluorophenyl)pyrrolidine-3-carboxylate1777616-64-4C13H15F2NO2
- Ethyl 4-(4-ethoxyphenyl)pyrrolidine-3-carboxylate1712331-26-4C15H21NO3
- Ethyl 4-(3,5-dimethylphenyl)pyrrolidine-3-carboxylate1772886-11-9C15H21NO2
- Ethyl 4-(3-ethoxyphenyl)pyrrolidine-3-carboxylate1772886-29-9C15H21NO3
- Ethyl 4-(2-fluoro-5-methylphenyl)pyrrolidine-3-carboxylate1986416-98-1C14H18FNO2
- Ethyl 4-(5-fluoro-2-methylphenyl)pyrrolidine-3-carboxylate1983044-72-9C14H18FNO2
- Methyl 4-(2,4-dimethoxyphenyl)pyrrolidine-3-carboxylate1715277-85-2C14H19NO4
- Methyl 4-[4-(methoxymethyl)phenyl]pyrrolidine-3-carboxylate1777440-86-4C14H19NO3
- Methyl 4-(4-fluoro-2-methylphenyl)pyrrolidine-3-carboxylate1772886-37-9C13H16FNO2
- Methyl 4-(2,6-difluorophenyl)pyrrolidine-3-carboxylate1713110-99-6C12H13F2NO2
- Methyl 4-(2,6-dimethylphenyl)pyrrolidine-3-carboxylate1713111-01-3C14H19NO2
- Methyl 4-[4-(propan-2-yl)phenyl]pyrrolidine-3-carboxylate1777615-00-5C15H21NO2
- Methyl 4-(3,4-dimethoxyphenyl)pyrrolidine-3-carboxylate1712553-81-5C14H19NO4
- Methyl 4-(2,5-difluorophenyl)pyrrolidine-3-carboxylate1777441-03-8C12H13F2NO2
- Methyl 4-(2,5-dimethylphenyl)pyrrolidine-3-carboxylate1772252-61-5C14H19NO2
- Methyl 4-(2,4-dimethylphenyl)pyrrolidine-3-carboxylate1712278-06-2C14H19NO2
- Methyl 4-(2-ethoxyphenyl)pyrrolidine-3-carboxylate1712330-54-5C14H19NO3
- Methyl 4-(2,5-dimethoxyphenyl)pyrrolidine-3-carboxylate1773282-73-7C14H19NO4
- Methyl 4-(3-fluoro-4-methoxyphenyl)pyrrolidine-3-carboxylate1712278-08-4C13H16FNO3
- Methyl 4-(4-fluoro-3-methylphenyl)pyrrolidine-3-carboxylate1774304-04-9C13H16FNO2
- Methyl 4-(3,4-difluorophenyl)pyrrolidine-3-carboxylate1713110-17-8C12H13F2NO2
Only the first 1,920 are listed here. Use the substructure search to filter further.
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