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Murcko scaffold

3-Phenylpyrrolidine scaffold

4,373 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
4,373
With full pages
8
Scaffold SMILES

c1ccc(C2CCNC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylpyrrolidine page
Murcko scaffold c1ccc(C2CCNC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,297 to 1,344 of 4,373 chemicals

trans-tert-Butyl 3-(aminomethyl)-4-phenylpyrrolidine-1-carboxylate hydrochloride chemical structure, C16H25ClN2O2, CAS 939823-97-9
trans-tert-Butyl 3-(aminomethyl)-4-phenylpyrrolidine-1-carboxylate hydrochloride
CAS 939823-97-9C16H25ClN2O2
trans-tert-Butyl-3-carbamoyl-4-phenylpyrrolidine-1-carboxylate chemical structure, C16H22N2O3, CAS 2381573-11-9
trans-tert-Butyl-3-carbamoyl-4-phenylpyrrolidine-1-carboxylate
CAS 2381573-11-9C16H22N2O3
1,1-Dimethylethyl (3R,4S)-3-cyano-4-phenyl-1-pyrrolidinecarboxylate chemical structure, C16H20N2O2, CAS 2281857-00-7
1,1-Dimethylethyl (3R,4S)-3-cyano-4-phenyl-1-pyrrolidinecarboxylate
CAS 2281857-00-7C16H20N2O2
tert-Butyl (4-(4-aminophenyl)pyrrolidin-3-yl)carbamate chemical structure, C15H23N3O2, CAS 1824448-76-1
tert-Butyl (4-(4-aminophenyl)pyrrolidin-3-yl)carbamate
CAS 1824448-76-1C15H23N3O2
Rel-methyl (3R,4S)-4-(4-bromophenyl)pyrrolidine-3-carboxylate hydrochloride chemical structure, C12H15BrClNO2, CAS 1956380-68-9
Rel-methyl (3R,4S)-4-(4-bromophenyl)pyrrolidine-3-carboxylate hydrochloride
CAS 1956380-68-9C12H15BrClNO2
trans-Methyl 4-(4-fluorophenyl)pyrrolidine-3-carboxylate hydrochloride chemical structure, C12H15ClFNO2, CAS 1236862-40-0
trans-Methyl 4-(4-fluorophenyl)pyrrolidine-3-carboxylate hydrochloride
CAS 1236862-40-0C12H15ClFNO2
Rel-methyl (3R,4S)-4-(p-tolyl)pyrrolidine-3-carboxylate hydrochloride chemical structure, C13H18ClNO2, CAS 1956380-71-4
Rel-methyl (3R,4S)-4-(p-tolyl)pyrrolidine-3-carboxylate hydrochloride
CAS 1956380-71-4C13H18ClNO2
(3S,4R)-tert-Butyl 3-hydroxy-4-phenylpyrrolidine-1-carboxylate hydrochloride chemical structure, C15H22ClNO3
(3S,4R)-tert-Butyl 3-hydroxy-4-phenylpyrrolidine-1-carboxylate hydrochloride
C15H22ClNO3
tert-Butyl trans-3-Hydroxy-4-phenylpyrrolidine-1-carboxylate chemical structure, C15H21NO3, CAS 849674-11-9
tert-Butyl trans-3-Hydroxy-4-phenylpyrrolidine-1-carboxylate
CAS 849674-11-9C15H21NO3
tert-Butyl 3-amino-4-(3-(difluoromethyl)phenyl)pyrrolidine-1-carboxylate chemical structure, C16H22F2N2O2, CAS 1366879-14-2
tert-Butyl 3-amino-4-(3-(difluoromethyl)phenyl)pyrrolidine-1-carboxylate
CAS 1366879-14-2C16H22F2N2O2
3-(3-Methoxyphenyl)pyrrolidine oxalate(2:1) chemical structure, C24H32N2O6, CAS 1610028-40-4
3-(3-Methoxyphenyl)pyrrolidine oxalate(2:1)
CAS 1610028-40-4C24H32N2O6
(4-(3-Ethoxyphenyl)pyrrolidin-3-yl)methanol chemical structure, C13H19NO2, CAS 1822798-84-4
(4-(3-Ethoxyphenyl)pyrrolidin-3-yl)methanol
CAS 1822798-84-4C13H19NO2
1-Boc-3-formyl-3-phenyl-pyrrolidine chemical structure, C16H21NO3, CAS 1414958-91-0
1-Boc-3-formyl-3-phenyl-pyrrolidine
CAS 1414958-91-0C16H21NO3
{2-[3-(2-Methylphenyl)-1-pyrrolidinyl]ethyl}amine dihydrochloride chemical structure, C13H22Cl2N2, CAS 1559059-73-2
{2-[3-(2-Methylphenyl)-1-pyrrolidinyl]ethyl}amine dihydrochloride
CAS 1559059-73-2C13H22Cl2N2
Methyl (3R,4S)-4-(2-methoxyphenyl)pyrrolidine-3-carboxylate hydrochloride chemical structure, C13H18ClNO3, CAS 1820575-86-7
Methyl (3R,4S)-4-(2-methoxyphenyl)pyrrolidine-3-carboxylate hydrochloride
CAS 1820575-86-7C13H18ClNO3
tert-Butyl N-{4-[4-(trifluoromethyl)phenyl]pyrrolidin-3-yl}carbamate chemical structure, C16H21F3N2O2, CAS 1823603-13-9
tert-Butyl N-{4-[4-(trifluoromethyl)phenyl]pyrrolidin-3-yl}carbamate
CAS 1823603-13-9C16H21F3N2O2
(4-(2-Methoxyphenyl)pyrrolidin-3-yl)methanol hydrochloride chemical structure, C12H18ClNO2, CAS 2173143-28-5
(4-(2-Methoxyphenyl)pyrrolidin-3-yl)methanol hydrochloride
CAS 2173143-28-5C12H18ClNO2
[4-(4-Chlorophenyl)pyrrolidin-3-yl]methanol hydrochloride chemical structure, C11H15Cl2NO, CAS 1955514-84-7
[4-(4-Chlorophenyl)pyrrolidin-3-yl]methanol hydrochloride
CAS 1955514-84-7C11H15Cl2NO
rac-[(3S,4R)-4-(2,5-Difluorophenyl)-3-pyrrolidinyl]methanol hydrochloride chemical structure, C11H14ClF2NO, CAS 1354485-08-7
rac-[(3S,4R)-4-(2,5-Difluorophenyl)-3-pyrrolidinyl]methanol hydrochloride
CAS 1354485-08-7C11H14ClF2NO
(4-(4-Chloro-2-fluorophenyl)pyrrolidin-3-yl)methanol hydrochloride chemical structure, C11H14Cl2FNO, CAS 2173088-77-0
(4-(4-Chloro-2-fluorophenyl)pyrrolidin-3-yl)methanol hydrochloride
CAS 2173088-77-0C11H14Cl2FNO
(4-(2-Fluorophenyl)pyrrolidin-3-yl)methanol hydrochloride chemical structure, C11H15ClFNO, CAS 2173125-13-6
(4-(2-Fluorophenyl)pyrrolidin-3-yl)methanol hydrochloride
CAS 2173125-13-6C11H15ClFNO
[4-(3,5-Dimethoxyphenyl)pyrrolidin-3-yl]methanol hydrochloride chemical structure, C13H20ClNO3, CAS 2173088-79-2
[4-(3,5-Dimethoxyphenyl)pyrrolidin-3-yl]methanol hydrochloride
CAS 2173088-79-2C13H20ClNO3
4-(3-Chlorophenyl)pyrrolidin-3-ol chemical structure, C10H12ClNO, CAS 1824312-59-5
4-(3-Chlorophenyl)pyrrolidin-3-ol
CAS 1824312-59-5C10H12ClNO
4-(3-Methoxyphenyl)pyrrolidin-3-ol chemical structure, C11H15NO2, CAS 1824449-55-9
4-(3-Methoxyphenyl)pyrrolidin-3-ol
CAS 1824449-55-9C11H15NO2