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Murcko scaffold

Ring system with 2 rings and 14 atoms

34 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
34
With full pages
14
Scaffold SMILES

O=S(=O)(c1ccccc1)N1C=NCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1C=NCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

2-Methyl-1-[(4-nitrophenyl)sulfonyl]-4,5-dihydro-1H-imidazole chemical structure, C10H11N3O4S, CAS 159350-46-6
2-Methyl-1-[(4-nitrophenyl)sulfonyl]-4,5-dihydro-1H-imidazole
CAS 159350-46-6C10H11N3O4S
1-[(4-Methylphenyl)sulfonyl]-2-(methylthio)-4,5-dihydro-1H-imidazole chemical structure, C11H14N2O2S2, CAS 673476-73-8
1-[(4-Methylphenyl)sulfonyl]-2-(methylthio)-4,5-dihydro-1H-imidazole
CAS 673476-73-8C11H14N2O2S2
1-((4-Chlorophenyl)sulfonyl)-2-(methylthio)-4,5-dihydro-1H-imidazole chemical structure, C10H11ClN2O2S2, CAS 673476-74-9
1-((4-Chlorophenyl)sulfonyl)-2-(methylthio)-4,5-dihydro-1H-imidazole
CAS 673476-74-9C10H11ClN2O2S2
2-Methyl-1-(toluene-4-sulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C11H14N2O2S, CAS 10449-82-8
2-Methyl-1-(toluene-4-sulfonyl)-4,5-dihydro-1H-imidazole
CAS 10449-82-8C11H14N2O2S
N-{4-[(2-Methyl-4,5-dihydro-1H-imidazol-1-yl)sulfonyl]phenyl}acetamide chemical structure, C12H15N3O3S, CAS 309927-48-8
N-{4-[(2-Methyl-4,5-dihydro-1H-imidazol-1-yl)sulfonyl]phenyl}acetamide
CAS 309927-48-8C12H15N3O3S
1-(5-Chloro-2-methoxyphenyl)sulfonyl-2-methyl-4,5-dihydroimidazole chemical structure, C11H13ClN2O3S, CAS 433689-21-5
1-(5-Chloro-2-methoxyphenyl)sulfonyl-2-methyl-4,5-dihydroimidazole
CAS 433689-21-5C11H13ClN2O3S
1-[(4-Chlorophenyl)sulfonyl]-2-methyl-4,5-dihydro-1H-imidazole chemical structure, C10H11ClN2O2S, CAS 181481-30-1
1-[(4-Chlorophenyl)sulfonyl]-2-methyl-4,5-dihydro-1H-imidazole
CAS 181481-30-1C10H11ClN2O2S
1-(4-Iodophenyl)sulfonyl-2-methyl-4,5-dihydroimidazole chemical structure, C10H11IN2O2S, CAS 433967-44-3
1-(4-Iodophenyl)sulfonyl-2-methyl-4,5-dihydroimidazole
CAS 433967-44-3C10H11IN2O2S
1-[(4-Fluorophenyl)sulfonyl]-2-methyl-4,5-dihydro-1H-imidazole chemical structure, C10H11FN2O2S, CAS 324778-27-0
1-[(4-Fluorophenyl)sulfonyl]-2-methyl-4,5-dihydro-1H-imidazole
CAS 324778-27-0C10H11FN2O2S
2-(Methylthio)-1-(phenylsulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C10H12N2O2S2, CAS 868216-40-4
2-(Methylthio)-1-(phenylsulfonyl)-4,5-dihydro-1H-imidazole
CAS 868216-40-4C10H12N2O2S2
1-(4-Bromophenyl)sulfonyl-2-methylsulfanyl-4,5-dihydroimidazole chemical structure, C10H11BrN2O2S2, CAS 868216-41-5
1-(4-Bromophenyl)sulfonyl-2-methylsulfanyl-4,5-dihydroimidazole
CAS 868216-41-5C10H11BrN2O2S2
1-(4-Fluorobenzenesulfonyl)-2-(methylsulfanyl)-4,5-dihydro-1H-imidazole chemical structure, C10H11FN2O2S2, CAS 868216-42-6
1-(4-Fluorobenzenesulfonyl)-2-(methylsulfanyl)-4,5-dihydro-1H-imidazole
CAS 868216-42-6C10H11FN2O2S2
1-((4-Methoxyphenyl)sulfonyl)-2-(methylthio)-4,5-dihydro-1H-imidazole chemical structure, C11H14N2O3S2, CAS 868216-43-7
1-((4-Methoxyphenyl)sulfonyl)-2-(methylthio)-4,5-dihydro-1H-imidazole
CAS 868216-43-7C11H14N2O3S2
2-Methylsulfanyl-1-(4-nitrophenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C10H11N3O4S2, CAS 868216-44-8
2-Methylsulfanyl-1-(4-nitrophenyl)sulfonyl-4,5-dihydroimidazole
CAS 868216-44-8C10H11N3O4S2
N-(4-((2-(Methylthio)-4,5-dihydro-1H-imidazol-1-yl)sulfonyl)phenyl)acetamide chemical structure, C12H15N3O3S2, CAS 868216-45-9
N-(4-((2-(Methylthio)-4,5-dihydro-1H-imidazol-1-yl)sulfonyl)phenyl)acetamide
CAS 868216-45-9C12H15N3O3S2
1-(Benzenesulfonyl)-2-ethylsulfanyl-4,5-dihydroimidazole chemical structure, C11H14N2O2S2, CAS 868216-48-2
1-(Benzenesulfonyl)-2-ethylsulfanyl-4,5-dihydroimidazole
CAS 868216-48-2C11H14N2O2S2
2-(Ethylthio)-1-tosyl-4,5-dihydro-1H-imidazole chemical structure, C12H16N2O2S2, CAS 868216-49-3
2-(Ethylthio)-1-tosyl-4,5-dihydro-1H-imidazole
CAS 868216-49-3C12H16N2O2S2
1-(4-Chlorophenyl)sulfonyl-2-ethylsulfanyl-4,5-dihydroimidazole chemical structure, C11H13ClN2O2S2, CAS 868216-50-6
1-(4-Chlorophenyl)sulfonyl-2-ethylsulfanyl-4,5-dihydroimidazole
CAS 868216-50-6C11H13ClN2O2S2
1-((4-Bromophenyl)sulfonyl)-2-(ethylthio)-4,5-dihydro-1H-imidazole chemical structure, C11H13BrN2O2S2, CAS 868216-51-7
1-((4-Bromophenyl)sulfonyl)-2-(ethylthio)-4,5-dihydro-1H-imidazole
CAS 868216-51-7C11H13BrN2O2S2
2-(Ethylthio)-1-((4-fluorophenyl)sulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C11H13FN2O2S2, CAS 868216-52-8
2-(Ethylthio)-1-((4-fluorophenyl)sulfonyl)-4,5-dihydro-1H-imidazole
CAS 868216-52-8C11H13FN2O2S2
2-(Ethylthio)-1-((4-methoxyphenyl)sulfonyl)-4,5-dihydro-1H-imidazole chemical structure, C12H16N2O3S2, CAS 868216-53-9
2-(Ethylthio)-1-((4-methoxyphenyl)sulfonyl)-4,5-dihydro-1H-imidazole
CAS 868216-53-9C12H16N2O3S2
2-Ethylsulfanyl-1-(4-nitrophenyl)sulfonyl-4,5-dihydroimidazole chemical structure, C11H13N3O4S2, CAS 868216-54-0
2-Ethylsulfanyl-1-(4-nitrophenyl)sulfonyl-4,5-dihydroimidazole
CAS 868216-54-0C11H13N3O4S2
N-[4-[(2-Ethylsulfanyl-4,5-dihydroimidazol-1-yl)sulfonyl]phenyl]acetamide chemical structure, C13H17N3O3S2, CAS 868216-55-1
N-[4-[(2-Ethylsulfanyl-4,5-dihydroimidazol-1-yl)sulfonyl]phenyl]acetamide
CAS 868216-55-1C13H17N3O3S2
1-[(4-Chloro-3-nitrophenyl)sulfonyl]-2-methyl-4,5-dihydro-1H-imidazole chemical structure, C10H10ClN3O4S, CAS 312279-47-3
1-[(4-Chloro-3-nitrophenyl)sulfonyl]-2-methyl-4,5-dihydro-1H-imidazole
CAS 312279-47-3C10H10ClN3O4S