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Murcko scaffold

Phthalimidine scaffold

1,194 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
1,194
With full pages
128
Scaffold SMILES

O=C1NCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Phthalimidine page
Murcko scaffold O=C1NCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 1,194 chemicals

Phthalimidine chemical structure, C8H7NO, CAS 480-91-1
Phthalimidine
CAS 480-91-1C8H7NO
1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy- chemical structure, C8H7NO2, CAS 26486-93-1
1H-Isoindol-1-one, 2,3-dihydro-3-hydroxy-
CAS 26486-93-1C8H7NO2
2-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-acetamide chemical structure, C10H10N2O2, CAS 30787-14-5
2-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-acetamide
CAS 30787-14-5C10H10N2O2
Porritoxin chemical structure, C17H23NO4, CAS 143114-82-3
Porritoxin
CAS 143114-82-3C17H23NO4
2-(3-Oxo-1H-isoindol-2-yl)pentanedioic acid chemical structure, C13H13NO5, CAS 26577-32-2
2-(3-Oxo-1H-isoindol-2-yl)pentanedioic acid
CAS 26577-32-2C13H13NO5
5-Amino-5-oxo-4-(1-oxoisoindolin-2-yl)pentanoic acid chemical structure, C13H14N2O4, CAS 75179-73-6
5-Amino-5-oxo-4-(1-oxoisoindolin-2-yl)pentanoic acid
CAS 75179-73-6C13H14N2O4
1,3-Dihydro-alpha-ethyl-1-oxo-2H-isoindole-2-acetamide chemical structure, C12H14N2O2, CAS 30787-15-6
1,3-Dihydro-alpha-ethyl-1-oxo-2H-isoindole-2-acetamide
CAS 30787-15-6C12H14N2O2
2-(2-Hydroxyethyl)-3H-isoindol-1-one chemical structure, C10H11NO2, CAS 5334-06-5
2-(2-Hydroxyethyl)-3H-isoindol-1-one
CAS 5334-06-5C10H11NO2
2-Methyl-2,3-dihydro-1H-isoindol-1-one chemical structure, C9H9NO, CAS 5342-91-6
2-Methyl-2,3-dihydro-1H-isoindol-1-one
CAS 5342-91-6C9H9NO
2-Nitroso-2,3-dihydro-1H-isoindol-1-one chemical structure, C8H6N2O2, CAS 5415-18-9
2-Nitroso-2,3-dihydro-1H-isoindol-1-one
CAS 5415-18-9C8H6N2O2
2-(3-Oxo-2,3-dihydro-1H-isoindol-1-yl)acetic acid chemical structure, C10H9NO3, CAS 3849-22-7
2-(3-Oxo-2,3-dihydro-1H-isoindol-1-yl)acetic acid
CAS 3849-22-7C10H9NO3
3-Buta-1,3-dien-2-yl-3-hydroxy-2-methylisoindol-1-one chemical structure, C13H13NO2, CAS 83451-46-1
3-Buta-1,3-dien-2-yl-3-hydroxy-2-methylisoindol-1-one
CAS 83451-46-1C13H13NO2
2,3-Dihydro-6-hydroxy-4-methoxy-5-methyl-1H-isoindol-1-one chemical structure, C10H11NO3, CAS 114090-43-6
2,3-Dihydro-6-hydroxy-4-methoxy-5-methyl-1H-isoindol-1-one
CAS 114090-43-6C10H11NO3
Zinnimidine chemical structure, C15H19NO3, CAS 148717-77-5
Zinnimidine
CAS 148717-77-5C15H19NO3
1H-Isoindol-1-one, 2,3-dihydro-2-hydroxy- chemical structure, C8H7NO2, CAS 6929-65-3
1H-Isoindol-1-one, 2,3-dihydro-2-hydroxy-
CAS 6929-65-3C8H7NO2
3-(1-Oxo-2,3-dihydro-1H-isoindol-2-yl)propanoic acid chemical structure, C11H11NO3, CAS 83747-30-2
3-(1-Oxo-2,3-dihydro-1H-isoindol-2-yl)propanoic acid
CAS 83747-30-2C11H11NO3
1H-Isoindol-1-one, 2-amino-2,3-dihydro- chemical structure, C8H8N2O, CAS 23990-34-3
1H-Isoindol-1-one, 2-amino-2,3-dihydro-
CAS 23990-34-3C8H8N2O
2-(1-Oxo-2,3-dihydro-1H-isoindol-2-yl)acetic acid chemical structure, C10H9NO3, CAS 39221-42-6
2-(1-Oxo-2,3-dihydro-1H-isoindol-2-yl)acetic acid
CAS 39221-42-6C10H9NO3
2-(6-Nitro-1-oxoisoindolin-2-yl)acetic acid chemical structure, C10H8N2O5, CAS 694499-69-9
2-(6-Nitro-1-oxoisoindolin-2-yl)acetic acid
CAS 694499-69-9C10H8N2O5
2-(6-Amino-1-oxoisoindolin-2-yl)acetic acid chemical structure, C10H10N2O3, CAS 491874-41-0
2-(6-Amino-1-oxoisoindolin-2-yl)acetic acid
CAS 491874-41-0C10H10N2O3
3-(6-Nitro-1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C11H10N2O5, CAS 620099-68-5
3-(6-Nitro-1-oxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid
CAS 620099-68-5C11H10N2O5
2-Methyl-3-oxoisoindoline-4-carboxylic acid chemical structure, C10H9NO3, CAS 14262-20-5
2-Methyl-3-oxoisoindoline-4-carboxylic acid
CAS 14262-20-5C10H9NO3
2-Isobutyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid chemical structure, C13H15NO3, CAS 626215-95-0
2-Isobutyl-3-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid
CAS 626215-95-0C13H15NO3
(S)-2-(1-Oxoisoindolin-2-yl)succinic acid chemical structure, C12H11NO5, CAS 298700-68-2
(S)-2-(1-Oxoisoindolin-2-yl)succinic acid
CAS 298700-68-2C12H11NO5