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Murcko scaffold

Ring system with 3 rings and 20 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
20
With full pages
11
Scaffold SMILES

O=C(NCc1ccc2c(c1)OCO2)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1ccc2c(c1)OCO2)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-bromophenyl)urea chemical structure, C15H13BrN2O3, CAS 328281-23-8
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-bromophenyl)urea
CAS 328281-23-8C15H13BrN2O3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3,4-dichlorophenyl)urea chemical structure, C15H12Cl2N2O3, CAS 65609-35-0
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3,4-dichlorophenyl)urea
CAS 65609-35-0C15H12Cl2N2O3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3-chlorophenyl)urea chemical structure, C15H13ClN2O3, CAS 444109-81-3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3-chlorophenyl)urea
CAS 444109-81-3C15H13ClN2O3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-methylphenyl)urea chemical structure, C16H16N2O3, CAS 710312-00-8
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-methylphenyl)urea
CAS 710312-00-8C16H16N2O3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-nitrophenyl)urea chemical structure, C15H13N3O5, CAS 380320-41-2
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-nitrophenyl)urea
CAS 380320-41-2C15H13N3O5
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-methoxy-4-nitrophenyl)urea chemical structure, C16H15N3O6, CAS 708213-86-9
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-methoxy-4-nitrophenyl)urea
CAS 708213-86-9C16H15N3O6
1-[1-(1,3-Benzodioxol-5-yl)ethyl]-3-[2-(trifluoromethyl)phenyl]urea chemical structure, C17H15F3N2O3, CAS 708243-73-6
1-[1-(1,3-Benzodioxol-5-yl)ethyl]-3-[2-(trifluoromethyl)phenyl]urea
CAS 708243-73-6C17H15F3N2O3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-ethylphenyl)urea chemical structure, C17H18N2O3, CAS 894498-17-0
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-ethylphenyl)urea
CAS 894498-17-0C17H18N2O3
Methyl 3-(1,3-benzodioxol-5-yl)-3-{[(2-fluoroanilino)carbonyl]amino}propanoate chemical structure, C18H17FN2O5, CAS 866144-47-0
Methyl 3-(1,3-benzodioxol-5-yl)-3-{[(2-fluoroanilino)carbonyl]amino}propanoate
CAS 866144-47-0C18H17FN2O5
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-fluorophenyl)urea chemical structure, C15H13FN2O3, CAS 894265-31-7
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-fluorophenyl)urea
CAS 894265-31-7C15H13FN2O3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2,3-dimethylphenyl)urea chemical structure, C17H18N2O3, CAS 894497-33-7
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2,3-dimethylphenyl)urea
CAS 894497-33-7C17H18N2O3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2,4-dimethylphenyl)urea chemical structure, C17H18N2O3, CAS 894497-42-8
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2,4-dimethylphenyl)urea
CAS 894497-42-8C17H18N2O3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-methoxy-5-methylphenyl)urea chemical structure, C17H18N2O4, CAS 896579-51-4
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-methoxy-5-methylphenyl)urea
CAS 896579-51-4C17H18N2O4
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3-methoxyphenyl)urea chemical structure, C16H16N2O4, CAS 553610-94-9
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3-methoxyphenyl)urea
CAS 553610-94-9C16H16N2O4
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-ethylphenyl)urea chemical structure, C17H18N2O3, CAS 894498-14-7
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-ethylphenyl)urea
CAS 894498-14-7C17H18N2O3
N-[(2H-1,3-Benzodioxol-5-yl)methyl]-N-butyl-N'-(2,4-dimethylphenyl)urea chemical structure, C21H26N2O3, CAS 88451-28-9
N-[(2H-1,3-Benzodioxol-5-yl)methyl]-N-butyl-N'-(2,4-dimethylphenyl)urea
CAS 88451-28-9C21H26N2O3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3-methylphenyl)urea chemical structure, C16H16N2O3, CAS 891424-94-5
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3-methylphenyl)urea
CAS 891424-94-5C16H16N2O3
Methyl 4-({[1-(1,3-benzodioxol-5-yl)ethyl]carbamoyl}amino)benzoate chemical structure, C18H18N2O5, CAS 932907-03-4
Methyl 4-({[1-(1,3-benzodioxol-5-yl)ethyl]carbamoyl}amino)benzoate
CAS 932907-03-4C18H18N2O5
1-[1-(1,3-Benzodioxol-5-yl)ethyl]-3-(4-ethylphenyl)urea chemical structure, C18H20N2O3, CAS 897340-15-7
1-[1-(1,3-Benzodioxol-5-yl)ethyl]-3-(4-ethylphenyl)urea
CAS 897340-15-7C18H20N2O3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-ethoxyphenyl)urea chemical structure, C17H18N2O4, CAS 896579-94-5
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-ethoxyphenyl)urea
CAS 896579-94-5C17H18N2O4