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Murcko scaffold

N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-2-phenoxyacetamide scaffold

21 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 22
Chemicals: 21
With full pages: 11

Scaffold SMILES

O=C(COc1ccccc1)Nc1ccc2c(c1)C(=O)NC2=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-2-phenoxyacetamide page

Murcko scaffold O=C(COc1ccccc1)Nc1ccc2c(c1)C(=O)NC2=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-2-phenoxyacetamide chemical structure, C16H12N2O4, CAS 378775-73-6

N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-2-phenoxyacetamide

CAS 378775-73-6C₁₆H₁₂N₂O₄

N-(1,3-Dioxoisoindol-5-yl)-2-(4-propan-2-ylphenoxy)acetamide chemical structure, C19H18N2O4, CAS 500263-57-0

N-(1,3-Dioxoisoindol-5-yl)-2-(4-propan-2-ylphenoxy)acetamide

CAS 500263-57-0C₁₉H₁₈N₂O₄

2-(2-Chlorophenoxy)-N-(1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide chemical structure, C16H11ClN2O4, CAS 500263-56-9

2-(2-Chlorophenoxy)-N-(1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide

CAS 500263-56-9C₁₆H₁₁ClN₂O₄

N-(1,3-Dioxoisoindol-5-yl)-2-(4-methoxyphenoxy)acetamide chemical structure, C17H14N2O5, CAS 667410-91-5

N-(1,3-Dioxoisoindol-5-yl)-2-(4-methoxyphenoxy)acetamide

CAS 667410-91-5C₁₇H₁₄N₂O₅

2-(4-Chlorophenoxy)-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide chemical structure, C17H13ClN2O4, CAS 330201-70-2

2-(4-Chlorophenoxy)-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide

CAS 330201-70-2C₁₇H₁₃ClN₂O₄

2-(3,4-Dimethylphenoxy)-N-(1,3-dioxoisoindol-5-yl)acetamide chemical structure, C18H16N2O4, CAS 518021-53-9

2-(3,4-Dimethylphenoxy)-N-(1,3-dioxoisoindol-5-yl)acetamide

CAS 518021-53-9C₁₈H₁₆N₂O₄

2-(4-tert-Butylphenoxy)-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide chemical structure, C21H22N2O4, CAS 445415-49-6

2-(4-tert-Butylphenoxy)-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide

CAS 445415-49-6C₂₁H₂₂N₂O₄

2-(4-Bromophenoxy)-N-(2-methyl-1,3-dioxoisoindol-5-yl)acetamide chemical structure, C17H13BrN2O4, CAS 433323-79-6

2-(4-Bromophenoxy)-N-(2-methyl-1,3-dioxoisoindol-5-yl)acetamide

CAS 433323-79-6C₁₇H₁₃BrN₂O₄

N-(2-Methyl-1,3-dioxoisoindol-5-yl)-2-(2-nitrophenoxy)acetamide chemical structure, C17H13N3O6, CAS 445415-50-9

N-(2-Methyl-1,3-dioxoisoindol-5-yl)-2-(2-nitrophenoxy)acetamide

CAS 445415-50-9C₁₇H₁₃N₃O₆

2-(4-Chloro-3,5-dimethylphenoxy)-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide chemical structure, C19H17ClN2O4, CAS 433245-05-7

2-(4-Chloro-3,5-dimethylphenoxy)-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide

CAS 433245-05-7C₁₉H₁₇ClN₂O₄

2-(4-Bromophenoxy)-N-(1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide chemical structure, C16H11BrN2O4, CAS 500264-30-2

2-(4-Bromophenoxy)-N-(1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)acetamide

CAS 500264-30-2C₁₆H₁₁BrN₂O₄

3-{1,3-Dioxo-5-[(phenoxyacetyl)amino]-1,3-dihydro-2H-isoindol-2-yl}propanoic acid chemical structure, C19H16N2O6, CAS 518023-16-0

3-{1,3-Dioxo-5-[(phenoxyacetyl)amino]-1,3-dihydro-2H-isoindol-2-yl}propanoic acid

CAS 518023-16-0C₁₉H₁₆N₂O₆

N-(1,3-Dioxoisoindol-5-yl)-2-(4-iodophenoxy)acetamide chemical structure, C16H11IN2O4, CAS 518008-62-3

N-(1,3-Dioxoisoindol-5-yl)-2-(4-iodophenoxy)acetamide

CAS 518008-62-3C₁₆H₁₁IN₂O₄

2-(4-tert-Butylphenoxy)-N-(1,3-dioxoisoindol-5-yl)acetamide chemical structure, C20H20N2O4, CAS 428838-48-6

2-(4-tert-Butylphenoxy)-N-(1,3-dioxoisoindol-5-yl)acetamide

CAS 428838-48-6C₂₀H₂₀N₂O₄

3-(5-{[(2-Methylphenoxy)acetyl]amino}-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C20H18N2O6, CAS 823837-61-2

3-(5-{[(2-Methylphenoxy)acetyl]amino}-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid

CAS 823837-61-2C₂₀H₁₈N₂O₆

2-(4-Butan-2-ylphenoxy)-N-(1,3-dioxoisoindol-5-yl)acetamide chemical structure, C20H20N2O4, CAS 518008-63-4

2-(4-Butan-2-ylphenoxy)-N-(1,3-dioxoisoindol-5-yl)acetamide

CAS 518008-63-4C₂₀H₂₀N₂O₄

N-(1,3-Dioxoisoindol-5-yl)-2-(4-methylphenoxy)acetamide chemical structure, C17H14N2O4, CAS 701257-21-8

N-(1,3-Dioxoisoindol-5-yl)-2-(4-methylphenoxy)acetamide

CAS 701257-21-8C₁₇H₁₄N₂O₄

3-(5-{[(4-Methylphenoxy)acetyl]amino}-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid chemical structure, C20H18N2O6, CAS 831233-16-0

3-(5-{[(4-Methylphenoxy)acetyl]amino}-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)propanoic acid

CAS 831233-16-0C₂₀H₁₈N₂O₆

2-(2,4-Dichlorophenoxy)-N-(1,3-dioxoisoindol-5-yl)acetamide chemical structure, C16H10Cl2N2O4, CAS 683235-52-1

2-(2,4-Dichlorophenoxy)-N-(1,3-dioxoisoindol-5-yl)acetamide

CAS 683235-52-1C₁₆H₁₀Cl₂N₂O₄

2-(4-Chlorophenoxy)-N-(1,3-dioxoisoindolin-5-yl)acetamide chemical structure, C16H11ClN2O4, CAS 683235-51-0

2-(4-Chlorophenoxy)-N-(1,3-dioxoisoindolin-5-yl)acetamide

CAS 683235-51-0C₁₆H₁₁ClN₂O₄

N-(1,3-Dioxoisoindol-5-yl)-2-(3-methylphenoxy)acetamide chemical structure, C17H14N2O4, CAS 847590-92-5

N-(1,3-Dioxoisoindol-5-yl)-2-(3-methylphenoxy)acetamide

CAS 847590-92-5C₁₇H₁₄N₂O₄