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Murcko scaffold

Ring system with 3 rings and 20 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
16
With full pages
12
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1ccc2nc[nH]c2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1ccc2nc[nH]c2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

1H-Benzimidazole-6-carboxylic acid, 2-[1-(3-nitrophenyl)ethylidene]hydrazide chemical structure, C16H13N5O3, CAS 299166-40-8
1H-Benzimidazole-6-carboxylic acid, 2-[1-(3-nitrophenyl)ethylidene]hydrazide
CAS 299166-40-8C16H13N5O3
N'-[(1Z)-1-(3,4-Dichlorophenyl)ethylidene]-1H-benzimidazole-6-carbohydrazide chemical structure, C16H12Cl2N4O, CAS 488813-35-0
N'-[(1Z)-1-(3,4-Dichlorophenyl)ethylidene]-1H-benzimidazole-6-carbohydrazide
CAS 488813-35-0C16H12Cl2N4O
N'-[(E)-(2,4,5-Trimethoxyphenyl)methylidene]-1H-benzimidazole-5-carbohydrazide chemical structure, C18H18N4O4, CAS 500270-37-1
N'-[(E)-(2,4,5-Trimethoxyphenyl)methylidene]-1H-benzimidazole-5-carbohydrazide
CAS 500270-37-1C18H18N4O4
N'-(3,4-Dimethoxybenzylidene)-1H-benzimidazole-6-carbohydrazide chemical structure, C17H16N4O3, CAS 299932-56-2
N'-(3,4-Dimethoxybenzylidene)-1H-benzimidazole-6-carbohydrazide
CAS 299932-56-2C17H16N4O3
N'-[(E)-(2,4-Dimethoxyphenyl)methylidene]-1H-benzimidazole-5-carbohydrazide chemical structure, C17H16N4O3, CAS 489414-34-8
N'-[(E)-(2,4-Dimethoxyphenyl)methylidene]-1H-benzimidazole-5-carbohydrazide
CAS 489414-34-8C17H16N4O3
Methyl 4-{(E)-[2-(1H-benzimidazol-6-ylcarbonyl)hydrazinylidene]methyl}benzoate chemical structure, C17H14N4O3, CAS 488825-79-2
Methyl 4-{(E)-[2-(1H-benzimidazol-6-ylcarbonyl)hydrazinylidene]methyl}benzoate
CAS 488825-79-2C17H14N4O3
N'-[(1E)-1-(4-Nitrophenyl)ethylidene]-1H-benzimidazole-5-carbohydrazide chemical structure, C16H13N5O3, CAS 488102-07-4
N'-[(1E)-1-(4-Nitrophenyl)ethylidene]-1H-benzimidazole-5-carbohydrazide
CAS 488102-07-4C16H13N5O3
N'-(2,3,4-Trimethoxybenzylidene)-1H-benzimidazole-6-carbohydrazide chemical structure, C18H18N4O4, CAS 487023-08-5
N'-(2,3,4-Trimethoxybenzylidene)-1H-benzimidazole-6-carbohydrazide
CAS 487023-08-5C18H18N4O4
N'-(4-(Diethylamino)benzylidene)-1H-benzimidazole-6-carbohydrazide chemical structure, C19H21N5O, CAS 500107-14-2
N'-(4-(Diethylamino)benzylidene)-1H-benzimidazole-6-carbohydrazide
CAS 500107-14-2C19H21N5O
N'-[(E)-(3,4,5-Trimethoxyphenyl)methylidene]-1H-benzimidazole-5-carbohydrazide chemical structure, C18H18N4O4, CAS 500107-37-9
N'-[(E)-(3,4,5-Trimethoxyphenyl)methylidene]-1H-benzimidazole-5-carbohydrazide
CAS 500107-37-9C18H18N4O4
N'-{2-Hydroxy-5-nitrobenzylidene}-2-methyl-1H-benzimidazole-6-carbohydrazide chemical structure, C16H13N5O4, CAS 341493-09-2
N'-{2-Hydroxy-5-nitrobenzylidene}-2-methyl-1H-benzimidazole-6-carbohydrazide
CAS 341493-09-2C16H13N5O4
N'-(3-Allyl-2-hydroxybenzylidene)-1H-benzimidazole-6-carbohydrazide chemical structure, C18H16N4O2, CAS 488100-26-1
N'-(3-Allyl-2-hydroxybenzylidene)-1H-benzimidazole-6-carbohydrazide
CAS 488100-26-1C18H16N4O2
N'-{(E)-[4-(diethylamino)-2-hydroxyphenyl]methylidene}-1H-benzimidazole-6-carbohydrazide chemical structure, C19H21N5O2, CAS 385404-43-3
N'-{(E)-[4-(diethylamino)-2-hydroxyphenyl]methylidene}-1H-benzimidazole-6-carbohydrazide
CAS 385404-43-3C19H21N5O2
N'-(4-Hydroxy-3-methoxybenzylidene)-1H-benzimidazole-6-carbohydrazide chemical structure, C16H14N4O3, CAS 299170-23-3
N'-(4-Hydroxy-3-methoxybenzylidene)-1H-benzimidazole-6-carbohydrazide
CAS 299170-23-3C16H14N4O3
N'-[(E)-(2-Hydroxy-3-methoxyphenyl)methylidene]-1H-benzimidazole-6-carbohydrazide chemical structure, C16H14N4O3, CAS 488108-09-4
N'-[(E)-(2-Hydroxy-3-methoxyphenyl)methylidene]-1H-benzimidazole-6-carbohydrazide
CAS 488108-09-4C16H14N4O3
N'-(3,4-Dihydroxybenzylidene)-1H-benzimidazole-6-carbohydrazide chemical structure, C15H12N4O3, CAS 487026-67-5
N'-(3,4-Dihydroxybenzylidene)-1H-benzimidazole-6-carbohydrazide
CAS 487026-67-5C15H12N4O3