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Murcko scaffold

1-(1,3-Benzodioxol-5-ylmethyl)-3-phenylthiourea scaffold

31 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
31
With full pages
16
Scaffold SMILES

S=C(NCc1ccc2c(c1)OCO2)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(1,3-Benzodioxol-5-ylmethyl)-3-phenylthiourea page
Murcko scaffold S=C(NCc1ccc2c(c1)OCO2)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-methylphenyl)thiourea chemical structure, C16H16N2O2S, CAS 384859-74-9
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-methylphenyl)thiourea
CAS 384859-74-9C16H16N2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3-fluorophenyl)thiourea chemical structure, C15H13FN2O2S, CAS 431918-69-3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3-fluorophenyl)thiourea
CAS 431918-69-3C15H13FN2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-methoxyphenyl)thiourea chemical structure, C16H16N2O3S, CAS 364749-81-5
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-methoxyphenyl)thiourea
CAS 364749-81-5C16H16N2O3S
1-(1,3-Benzodioxol-5-ylmethyl)-3-phenylthiourea chemical structure, C15H14N2O2S, CAS 65609-34-9
1-(1,3-Benzodioxol-5-ylmethyl)-3-phenylthiourea
CAS 65609-34-9C15H14N2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-methylphenyl)thiourea chemical structure, C16H16N2O2S, CAS 431073-80-2
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-methylphenyl)thiourea
CAS 431073-80-2C16H16N2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-chloro-2-methylphenyl)thiourea chemical structure, C16H15ClN2O2S, CAS 433259-23-5
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-chloro-2-methylphenyl)thiourea
CAS 433259-23-5C16H15ClN2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2,4-dimethylphenyl)thiourea chemical structure, C17H18N2O2S, CAS 433312-27-7
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2,4-dimethylphenyl)thiourea
CAS 433312-27-7C17H18N2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3,5-dimethoxyphenyl)thiourea chemical structure, C17H18N2O4S, CAS 433317-97-6
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3,5-dimethoxyphenyl)thiourea
CAS 433317-97-6C17H18N2O4S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2,4-dimethoxyphenyl)thiourea chemical structure, C17H18N2O4S, CAS 433319-00-7
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2,4-dimethoxyphenyl)thiourea
CAS 433319-00-7C17H18N2O4S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2,5-dimethylphenyl)thiourea chemical structure, C17H18N2O2S, CAS 433324-38-0
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2,5-dimethylphenyl)thiourea
CAS 433324-38-0C17H18N2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3-methoxyphenyl)thiourea chemical structure, C16H16N2O3S, CAS 431916-59-5
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3-methoxyphenyl)thiourea
CAS 431916-59-5C16H16N2O3S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-fluorophenyl)thiourea chemical structure, C15H13FN2O2S, CAS 313381-17-8
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-fluorophenyl)thiourea
CAS 313381-17-8C15H13FN2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-chlorophenyl)thiourea chemical structure, C15H13ClN2O2S, CAS 385394-43-4
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-chlorophenyl)thiourea
CAS 385394-43-4C15H13ClN2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-ethylphenyl)thiourea chemical structure, C17H18N2O2S, CAS 609822-73-3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-ethylphenyl)thiourea
CAS 609822-73-3C17H18N2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-chlorophenyl)thiourea chemical structure, C15H13ClN2O2S, CAS 428503-47-3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-chlorophenyl)thiourea
CAS 428503-47-3C15H13ClN2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-fluorophenyl)thiourea chemical structure, C15H13FN2O2S, CAS 428825-85-8
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-fluorophenyl)thiourea
CAS 428825-85-8C15H13FN2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3-methylphenyl)thiourea chemical structure, C16H16N2O2S, CAS 428840-59-9
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3-methylphenyl)thiourea
CAS 428840-59-9C16H16N2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-methoxyphenyl)thiourea chemical structure, C16H16N2O3S, CAS 406925-57-3
1-(1,3-Benzodioxol-5-ylmethyl)-3-(2-methoxyphenyl)thiourea
CAS 406925-57-3C16H16N2O3S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-ethoxyphenyl)thiourea chemical structure, C17H18N2O3S, CAS 384370-60-9
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-ethoxyphenyl)thiourea
CAS 384370-60-9C17H18N2O3S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3,4-dimethylphenyl)thiourea chemical structure, C17H18N2O2S, CAS 502743-78-4
1-(1,3-Benzodioxol-5-ylmethyl)-3-(3,4-dimethylphenyl)thiourea
CAS 502743-78-4C17H18N2O2S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-chloro-2,5-dimethoxyphenyl)thiourea chemical structure, C17H17ClN2O4S, CAS 664968-88-1
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-chloro-2,5-dimethoxyphenyl)thiourea
CAS 664968-88-1C17H17ClN2O4S
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-sulfamoylphenyl)thiourea chemical structure, C15H15N3O4S2, CAS 627063-44-9
1-(1,3-Benzodioxol-5-ylmethyl)-3-(4-sulfamoylphenyl)thiourea
CAS 627063-44-9C15H15N3O4S2
Methyl (4-{[(1,3-benzodioxol-5-ylmethyl)carbamothioyl]amino}phenyl)acetate chemical structure, C18H18N2O4S, CAS 516457-42-4
Methyl (4-{[(1,3-benzodioxol-5-ylmethyl)carbamothioyl]amino}phenyl)acetate
CAS 516457-42-4C18H18N2O4S
Dimethyl 5-{[(1,3-benzodioxol-5-ylmethyl)carbamothioyl]amino}benzene-1,3-dicarboxylate chemical structure, C19H18N2O6S, CAS 708992-58-9
Dimethyl 5-{[(1,3-benzodioxol-5-ylmethyl)carbamothioyl]amino}benzene-1,3-dicarboxylate
CAS 708992-58-9C19H18N2O6S