Murcko scaffold
Ring system with 4 rings and 22 atoms
49 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 22
- Chemicals
- 49
- With full pages
- 19
Scaffold SMILES
O=C(NC1C(=O)N2CCSC12)c1conc1-c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 49 chemicals
![6-{[3-(2-Chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid chemical structure, C19H18ClN3O5S, CAS 7060-81-3](/s/LQOLIRLGBULYKD-UHFFFAOYSA-N.svg)
6-{[3-(2-Chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
CAS 7060-81-3C19H18ClN3O5S
![3,3-Dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid chemical structure, C19H19N3O5S, CAS 740789-23-5](/s/UWYHMGVUTGAWSP-UHFFFAOYSA-N.svg)
3,3-Dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
CAS 740789-23-5C19H19N3O5S
Cloxacillin
CAS 61-72-3C19H18ClN3O5S
Oxacillin
CAS 66-79-5C19H19N3O5S
Dicloxacillin
CAS 3116-76-5C19H17Cl2N3O5S
Flucloxacillin
CAS 5250-39-5C19H17ClFN3O5S
Cloxacillin benzathine
CAS 23736-58-5C54H56Cl2N8O10S2
Combipenix
CAS 51004-51-4C35H36Cl2N6O9S2
5-Hydroxymethylflucloxacillin
CAS 75524-31-1C19H17ClFN3O6S
RefChem:1071632
CAS 8067-85-4C35H38N6O9S2
Versaclox
CAS 37368-26-6C38H40Cl2N6O9S2
Viccillin S (combination)
CAS 37203-95-5C35H37ClN6O9S2
Flucexin
CAS 79806-18-1C35H34ClFN6O9S2
Oxacillin benzathine
CAS 916-96-1C54H58N8O10S2
![(2S,5R,6R)-6-[[3-(2-Chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, N,N'-dibenzylethane-1,2-diamine chemical structure, C35H38ClN5O5S, CAS 27487-35-0](/s/OUMOALQYXBRQFX-SLINCCQESA-N.svg)
(2S,5R,6R)-6-[[3-(2-Chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, N,N'-dibenzylethane-1,2-diamine
CAS 27487-35-0C35H38ClN5O5S
![Sodium, (2S,5R,6R)-6-[[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, hydrate chemical structure, C19H19Cl2N3NaO6S](/s/QBFCIKYALGTFHK-VICXVTCVSA-N.svg)
Sodium, (2S,5R,6R)-6-[[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, hydrate
C19H19Cl2N3NaO6S
Dicloxacillin sodium
CAS 343-55-5C19H16Cl2N3NaO5S
Floxacillin sodium
CAS 1847-24-1C19H16ClFN3NaO5S
Oxacillin sodium salt
CAS 1173-88-2C19H18N3NaO5S
Cloxacillin sodium
CAS 642-78-4C19H17ClN3NaO5S
Tegopen
CAS 7081-44-9C19H19ClN3NaO6S
Dicloxacillin sodium monohydrate
CAS 13412-64-1C19H18Cl2N3NaO6S
Oxacillin sodium
CAS 7240-38-2C19H20N3NaO6S
Flucloxacillin sodium monohydrate
CAS 34214-51-2C19H18ClFN3NaO6S
- Floxacillin magnesium anhydrous40182-54-5C38H32Cl2F2MgN6O10S2
- Cloxacillin methyl ester22418-07-1C20H20ClN3O5S
- Pharmakon1600-01500238C19H17Cl2N3NaO5S+
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-6-[[(5-methyl-3-phenyl-4-isoxazolyl)carbonyl]amino]-7-oxo-, sodium salt (1:1), (2S,5R,6R)-C19H19N3NaO5S
- C19H17Cl2N3NaO5SC19H17Cl2N3NaO5S
- Oxaclen18303-77-0C35H39N5O5S
- Flucloxacillin magnesium octahydrate58486-36-5C38H48Cl2F2MgN6O18S2
- Ampiclox62713-27-3C35H36ClN6NaO9S2
- Magnapen56749-84-9C35H36ClFN6O9S2
- Suprapen57456-43-6C35H36ClFN6O10S2
- Dirimen57855-64-8C33H31Cl2N11O9S4
- Aluminum dicloxacillin trihydrate23232-35-1C57H54AlCl6N9O18S3
- 5'-Hydroxymethyl dicloxacillin40125-80-2C19H17Cl2N3O6S
- Thioxacillin potassium salt5053-35-0C19H19N3O4S2
- Aluminum, tris(6-[[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate), trihydrate1629016-94-9C57H54AlCl6N9O18S3
- 2-Oxopropyl (2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate57808-42-1C22H22ClN3O6S
- Cloxacillin sodium impurity 75053-36-1C19H18ClN3O4S2
- Oxacillin impurity G724695-30-1C19H18ClN3O5S
- Oxacillin EP impurity G21106-64-9C19H18ClN3O5S
- Aluminum, tris((2S,5R,6R)-6-[[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate), nonahydrateC57H66AlCl6N9O24S3
- Calcium bis((2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate)54661-64-2C38H34CaCl2N6O10S2
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, calcium salt (2:1), [2S-(2I+/-,5I+/-,6I(2))]-54661-61-9C38H32CaCl2F2N6O10S2
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, sodium salt (1:1), (2S,5R,6R)-, mixt. with (4R,5S,6S)-3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid2227136-64-1C36H41Cl2N6NaO10S2
- Pyridinium, 1-[[2-carboxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt, (6R-trans)-, mixt. with [2S-(2I+/-,5I+/-,6I(2))]-6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid39474-62-9C38H35ClN6O9S3