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Murcko scaffold

Ring system with 4 rings and 27 atoms

18 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
18
With full pages
1
Scaffold SMILES

O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

Benzamide, 4-bromo-N-(2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)- chemical structure, C23H18BrN3O2, CAS 111035-59-7
Benzamide, 4-bromo-N-(2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-
CAS 111035-59-7C23H18BrN3O2
N-[[(3R)-1-(2,2,2-Trifluoroethyl)-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin]-3-yl]-3,5-dichlorobenzamide chemical structure, C24H16Cl2F3N3O2, CAS 177954-58-4
N-[[(3R)-1-(2,2,2-Trifluoroethyl)-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin]-3-yl]-3,5-dichlorobenzamide
CAS 177954-58-4C24H16Cl2F3N3O2
4-Chloro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide chemical structure, C23H17ClFN3O2, CAS 103343-56-2
4-Chloro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide
CAS 103343-56-2C23H17ClFN3O2
3-Bromo-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide chemical structure, C23H17BrFN3O2, CAS 2624122-76-3
3-Bromo-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide
CAS 2624122-76-3C23H17BrFN3O2
4-Bromo-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide chemical structure, C23H17BrFN3O2, CAS 2624117-85-5
4-Bromo-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide
CAS 2624117-85-5C23H17BrFN3O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-iodobenzamide chemical structure, C23H17FIN3O2, CAS 2624115-35-9
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-iodobenzamide
CAS 2624115-35-9C23H17FIN3O2
2-Bromo-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide chemical structure, C23H17BrFN3O2, CAS 2624115-65-5
2-Bromo-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide
CAS 2624115-65-5C23H17BrFN3O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-3-iodobenzamide chemical structure, C23H17FIN3O2, CAS 2624121-60-2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-3-iodobenzamide
CAS 2624121-60-2C23H17FIN3O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-2-iodobenzamide chemical structure, C23H17FIN3O2, CAS 2624121-82-8
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-2-iodobenzamide
CAS 2624121-82-8C23H17FIN3O2
2-Chloro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide chemical structure, C23H17ClFN3O2, CAS 2624129-15-1
2-Chloro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide
CAS 2624129-15-1C23H17ClFN3O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-propylbenzamide chemical structure, C26H24FN3O2, CAS 2624128-76-1
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-propylbenzamide
CAS 2624128-76-1C26H24FN3O2
4-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide chemical structure, C23H17F2N3O2, CAS 2624121-63-5
4-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide
CAS 2624121-63-5C23H17F2N3O2
3-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide chemical structure, C23H17F2N3O2, CAS 2624128-87-4
3-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide
CAS 2624128-87-4C23H17F2N3O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-3-hydroxybenzamide chemical structure, C23H18FN3O3, CAS 2624115-69-9
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-3-hydroxybenzamide
CAS 2624115-69-9C23H18FN3O3
3-Chloro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide chemical structure, C23H17ClFN3O2, CAS 2624122-74-1
3-Chloro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide
CAS 2624122-74-1C23H17ClFN3O2
2-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide chemical structure, C23H17F2N3O2, CAS 2624117-88-8
2-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]benzamide
CAS 2624117-88-8C23H17F2N3O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-hydroxybenzamide chemical structure, C23H18FN3O3, CAS 2624122-81-0
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-hydroxybenzamide
CAS 2624122-81-0C23H18FN3O3
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-2-hydroxybenzamide chemical structure, C23H18FN3O3, CAS 2624122-01-4
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-2-hydroxybenzamide
CAS 2624122-01-4C23H18FN3O3