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Murcko scaffold

Ring system with 3 rings and 22 atoms

22 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
22
With full pages
12
Scaffold SMILES

O=C(NCC(c1cccs1)N1CCOCC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCC(c1cccs1)N1CCOCC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

4-(Dimethylamino)-N-(2-morpholin-4-yl-2-thiophen-2-ylethyl)benzamide chemical structure, C19H25N3O2S, CAS 782454-84-6
4-(Dimethylamino)-N-(2-morpholin-4-yl-2-thiophen-2-ylethyl)benzamide
CAS 782454-84-6C19H25N3O2S
4-Ethoxy-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide chemical structure, C19H24N2O3S, CAS 782454-88-0
4-Ethoxy-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide
CAS 782454-88-0C19H24N2O3S
3-Methoxy-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide chemical structure, C18H22N2O3S, CAS 784188-86-9
3-Methoxy-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide
CAS 784188-86-9C18H22N2O3S
N-(1-Morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide chemical structure, C18H22N2O2S, CAS 887205-05-2
N-(1-Morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide
CAS 887205-05-2C18H22N2O2S
2-Methyl-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide chemical structure, C19H24N2O2S, CAS 887205-08-5
2-Methyl-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide
CAS 887205-08-5C19H24N2O2S
3-Methyl-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide chemical structure, C19H24N2O2S, CAS 887205-11-0
3-Methyl-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide
CAS 887205-11-0C19H24N2O2S
4-Methyl-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide chemical structure, C19H24N2O2S, CAS 887205-15-4
4-Methyl-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide
CAS 887205-15-4C19H24N2O2S
3,4-Dimethyl-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide chemical structure, C20H26N2O2S, CAS 887205-18-7
3,4-Dimethyl-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide
CAS 887205-18-7C20H26N2O2S
4-tert-Butyl-N-[1-(morpholin-4-yl)-1-(thiophen-2-yl)propan-2-yl]benzamide chemical structure, C22H30N2O2S, CAS 887205-21-2
4-tert-Butyl-N-[1-(morpholin-4-yl)-1-(thiophen-2-yl)propan-2-yl]benzamide
CAS 887205-21-2C22H30N2O2S
4-Ethoxy-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide chemical structure, C20H26N2O3S, CAS 887205-23-4
4-Ethoxy-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide
CAS 887205-23-4C20H26N2O3S
3-Chloro-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide chemical structure, C18H21ClN2O2S, CAS 887205-26-7
3-Chloro-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide
CAS 887205-26-7C18H21ClN2O2S
4-Chloro-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide chemical structure, C18H21ClN2O2S, CAS 887205-30-3
4-Chloro-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzamide
CAS 887205-30-3C18H21ClN2O2S
2,6-Dimethoxy-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzamide chemical structure, C19H24N2O4S, CAS 899975-19-0
2,6-Dimethoxy-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzamide
CAS 899975-19-0C19H24N2O4S
3,4,5-Trimethoxy-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide chemical structure, C20H26N2O5S, CAS 898475-79-1
3,4,5-Trimethoxy-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide
CAS 898475-79-1C20H26N2O5S
2-Fluoro-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide chemical structure, C17H19FN2O2S, CAS 898601-38-2
2-Fluoro-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide
CAS 898601-38-2C17H19FN2O2S
2-Bromo-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide chemical structure, C17H19BrN2O2S, CAS 898495-15-3
2-Bromo-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide
CAS 898495-15-3C17H19BrN2O2S
4-Chloro-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide chemical structure, C17H19ClN2O2S, CAS 953846-66-7
4-Chloro-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide
CAS 953846-66-7C17H19ClN2O2S
3-Methyl-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide chemical structure, C18H22N2O2S, CAS 950164-16-6
3-Methyl-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide
CAS 950164-16-6C18H22N2O2S
4-tert-Butyl-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide chemical structure, C21H28N2O2S, CAS 953847-23-9
4-tert-Butyl-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide
CAS 953847-23-9C21H28N2O2S
4-Bromo-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide chemical structure, C17H19BrN2O2S, CAS 924132-12-7
4-Bromo-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzamide
CAS 924132-12-7C17H19BrN2O2S
2-Chloro-6-fluoro-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzamide chemical structure, C17H18ClFN2O2S, CAS 899975-21-4
2-Chloro-6-fluoro-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzamide
CAS 899975-21-4C17H18ClFN2O2S
4,5-Dimethoxy-N-(2-morpholino-2-(thiophen-2-yl)ethyl)-2-nitrobenzamide chemical structure, C19H23N3O6S, CAS 899744-67-3
4,5-Dimethoxy-N-(2-morpholino-2-(thiophen-2-yl)ethyl)-2-nitrobenzamide
CAS 899744-67-3C19H23N3O6S