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Murcko scaffold

Ring system with 3 rings and 23 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
21
With full pages
4
Scaffold SMILES

O=S(=O)(NCC(c1cccs1)N1CCOCC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(NCC(c1cccs1)N1CCOCC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

N-(1-Morpholino-1-(thiophen-2-yl)propan-2-yl)benzenesulfonamide chemical structure, C17H22N2O3S2, CAS 847380-96-5
N-(1-Morpholino-1-(thiophen-2-yl)propan-2-yl)benzenesulfonamide
CAS 847380-96-5C17H22N2O3S2
4-Methyl-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzenesulfonamide chemical structure, C18H24N2O3S2, CAS 847380-97-6
4-Methyl-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzenesulfonamide
CAS 847380-97-6C18H24N2O3S2
4-Fluoro-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzenesulfonamide chemical structure, C17H21FN2O3S2, CAS 847381-00-4
4-Fluoro-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzenesulfonamide
CAS 847381-00-4C17H21FN2O3S2
4-Bromo-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzenesulfonamide chemical structure, C17H21BrN2O3S2, CAS 847380-99-8
4-Bromo-N-(1-morpholino-1-(thiophen-2-yl)propan-2-yl)benzenesulfonamide
CAS 847380-99-8C17H21BrN2O3S2
N-(1-Morpholino-1-(thiophen-2-yl)propan-2-yl)-4-nitrobenzenesulfonamide chemical structure, C17H21N3O5S2, CAS 847381-01-5
N-(1-Morpholino-1-(thiophen-2-yl)propan-2-yl)-4-nitrobenzenesulfonamide
CAS 847381-01-5C17H21N3O5S2
2-Methoxy-5-methyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide chemical structure, C18H24N2O4S2, CAS 899955-55-6
2-Methoxy-5-methyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide
CAS 899955-55-6C18H24N2O4S2
4-Methoxy-3-methyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide chemical structure, C18H24N2O4S2, CAS 899999-45-2
4-Methoxy-3-methyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide
CAS 899999-45-2C18H24N2O4S2
2-Methoxy-4,5-dimethyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide chemical structure, C19H26N2O4S2, CAS 899747-82-1
2-Methoxy-4,5-dimethyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide
CAS 899747-82-1C19H26N2O4S2
2,5-Dimethoxy-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide chemical structure, C18H24N2O5S2, CAS 899955-59-0
2,5-Dimethoxy-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide
CAS 899955-59-0C18H24N2O5S2
3,4-Dimethyl-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzene-1-sulfonamide chemical structure, C18H24N2O3S2, CAS 941996-95-8
3,4-Dimethyl-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzene-1-sulfonamide
CAS 941996-95-8C18H24N2O3S2
2,5-Dimethyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide chemical structure, C18H24N2O3S2, CAS 899999-39-4
2,5-Dimethyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide
CAS 899999-39-4C18H24N2O3S2
4-Fluoro-2-methyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide chemical structure, C17H21FN2O3S2, CAS 899955-51-2
4-Fluoro-2-methyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide
CAS 899955-51-2C17H21FN2O3S2
4-Fluoro-3-methyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide chemical structure, C17H21FN2O3S2, CAS 899999-41-8
4-Fluoro-3-methyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide
CAS 899999-41-8C17H21FN2O3S2
4-Chloro-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide chemical structure, C16H19ClN2O3S2, CAS 899955-53-4
4-Chloro-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide
CAS 899955-53-4C16H19ClN2O3S2
3-Chloro-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzene-1-sulfonamide chemical structure, C16H19ClN2O3S2, CAS 899999-43-0
3-Chloro-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzene-1-sulfonamide
CAS 899999-43-0C16H19ClN2O3S2
2,4,5-Trimethyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide chemical structure, C19H26N2O3S2, CAS 920356-42-9
2,4,5-Trimethyl-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide
CAS 920356-42-9C19H26N2O3S2
4-Ethoxy-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzene-1-sulfonamide chemical structure, C18H24N2O4S2, CAS 941872-45-3
4-Ethoxy-N-[2-(morpholin-4-yl)-2-(thiophen-2-yl)ethyl]benzene-1-sulfonamide
CAS 941872-45-3C18H24N2O4S2
N-(2-Morpholino-2-(thiophen-2-yl)ethyl)-4-nitrobenzenesulfonamide chemical structure, C16H19N3O5S2, CAS 899747-80-9
N-(2-Morpholino-2-(thiophen-2-yl)ethyl)-4-nitrobenzenesulfonamide
CAS 899747-80-9C16H19N3O5S2
N-[2-(Morpholin-4-yl)-2-(thiophen-2-yl)ethyl]-3-nitrobenzene-1-sulfonamide chemical structure, C16H19N3O5S2, CAS 941977-65-7
N-[2-(Morpholin-4-yl)-2-(thiophen-2-yl)ethyl]-3-nitrobenzene-1-sulfonamide
CAS 941977-65-7C16H19N3O5S2
N-(2-Morpholino-2-(thiophen-2-yl)ethyl)-2-nitrobenzenesulfonamide chemical structure, C16H19N3O5S2, CAS 941934-30-1
N-(2-Morpholino-2-(thiophen-2-yl)ethyl)-2-nitrobenzenesulfonamide
CAS 941934-30-1C16H19N3O5S2
2,5-Difluoro-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide chemical structure, C16H18F2N2O3S2, CAS 920356-34-9
2,5-Difluoro-N-(2-morpholino-2-(thiophen-2-yl)ethyl)benzenesulfonamide
CAS 920356-34-9C16H18F2N2O3S2