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Murcko scaffold

Ring system with 4 rings and 21 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
14
With full pages
4
Scaffold SMILES

c1ccc(Nc2nc(-c3cnc4ccccn34)cs2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2nc(-c3cnc4ccccn34)cs2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

2-Thiazolamine, 4-(2-methylimidazo[1,2-a]pyridin-3-yl)-N-phenyl- chemical structure, C17H14N4S, CAS 315703-48-1
2-Thiazolamine, 4-(2-methylimidazo[1,2-a]pyridin-3-yl)-N-phenyl-
CAS 315703-48-1C17H14N4S
4-(2-Methylimidazo[1,2-a]pyridin-3-yl)-N-(3-methylphenyl)-1,3-thiazol-2-amine chemical structure, C18H16N4S, CAS 315703-51-6
4-(2-Methylimidazo[1,2-a]pyridin-3-yl)-N-(3-methylphenyl)-1,3-thiazol-2-amine
CAS 315703-51-6C18H16N4S
N-(5-Chloro-2-methoxyphenyl)-4-{2-methylimidazo[1,2-A]pyridin-3-YL}-1,3-thiazol-2-amine chemical structure, C18H15ClN4OS, CAS 428503-75-7
N-(5-Chloro-2-methoxyphenyl)-4-{2-methylimidazo[1,2-A]pyridin-3-YL}-1,3-thiazol-2-amine
CAS 428503-75-7C18H15ClN4OS
RefChem:150500 chemical structure, C19H18N4OS, CAS 315703-52-7
RefChem:150500
CAS 315703-52-7C19H18N4OS
4-[[4-(2,7-Dimethylimidazo[1,2-a]pyridin-3-yl)-2-thiazolyl]amino]benzoic Acid chemical structure, C19H16N4O2S, CAS 315704-15-5
4-[[4-(2,7-Dimethylimidazo[1,2-a]pyridin-3-yl)-2-thiazolyl]amino]benzoic Acid
CAS 315704-15-5C19H16N4O2S
N-(4-{[4-(2,7-Dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)acetamide chemical structure, C20H19N5OS, CAS 315704-21-3
N-(4-{[4-(2,7-Dimethylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)acetamide
CAS 315704-21-3C20H19N5OS
N-(2-Methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-amine chemical structure, C18H16N4OS, CAS 315703-56-1
N-(2-Methoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-amine
CAS 315703-56-1C18H16N4OS
N-(2-Ethylphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-amine chemical structure, C19H18N4S, CAS 6531-84-6
N-(2-Ethylphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-amine
CAS 6531-84-6C19H18N4S
4-{[4-(2-Methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenol chemical structure, C17H14N4OS, CAS 315703-60-7
4-{[4-(2-Methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenol
CAS 315703-60-7C17H14N4OS
3-[[4-(2-Methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolyl]amino]phenol chemical structure, C17H14N4OS, CAS 315703-53-8
3-[[4-(2-Methylimidazo[1,2-a]pyridin-3-yl)-2-thiazolyl]amino]phenol
CAS 315703-53-8C17H14N4OS
4-Imidazo[1,2-a]pyridin-3-yl-N-(4-methoxyphenyl)-2-thiazolamine chemical structure, C17H14N4OS, CAS 420126-41-6
4-Imidazo[1,2-a]pyridin-3-yl-N-(4-methoxyphenyl)-2-thiazolamine
CAS 420126-41-6C17H14N4OS
Antitumor agent-3 chemical structure, C18H10F6N4S, CAS 420126-30-3
Antitumor agent-3
CAS 420126-30-3C18H10F6N4S
Pkm2-IN-6 chemical structure, C17H14N4OS, CAS 771467-00-6
Pkm2-IN-6
CAS 771467-00-6C17H14N4OS
4-[(4-Imidazo[1,2-a]pyridin-3-yl-1,3-thiazol-2-yl)amino]phenol chemical structure, C16H12N4OS, CAS 792898-18-1
4-[(4-Imidazo[1,2-a]pyridin-3-yl-1,3-thiazol-2-yl)amino]phenol
CAS 792898-18-1C16H12N4OS