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Murcko scaffold

Azlactone scaffold

60 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
60
With full pages
2
Scaffold SMILES

O=C1CN=C(c2ccccc2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Azlactone page
Murcko scaffold O=C1CN=C(c2ccccc2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 60 chemicals

Azlactone chemical structure, C9H7NO2, CAS 1199-01-5
Azlactone
CAS 1199-01-5C9H7NO2
4-Isopropyl-2-phenyl-2-oxazoline-5-one chemical structure, C12H13NO2, CAS 5839-93-0
4-Isopropyl-2-phenyl-2-oxazoline-5-one
CAS 5839-93-0C12H13NO2
4,4-Dimethyl-2-phenyl-1,3-oxazol-5(4H)-one chemical structure, C11H11NO2, CAS 7563-05-5
4,4-Dimethyl-2-phenyl-1,3-oxazol-5(4H)-one
CAS 7563-05-5C11H11NO2
4-Methyl-2-phenyl-2-oxazoline-5-one chemical structure, C10H9NO2, CAS 13302-43-7
4-Methyl-2-phenyl-2-oxazoline-5-one
CAS 13302-43-7C10H9NO2
4-Isobutyl-2-phenyl-2-oxazoline-5-one chemical structure, C13H15NO2, CAS 25163-98-8
4-Isobutyl-2-phenyl-2-oxazoline-5-one
CAS 25163-98-8C13H15NO2
5(4H)-Oxazolone, 4-(1,1-dimethylethyl)-2-phenyl- chemical structure, C13H15NO2, CAS 71953-55-4
5(4H)-Oxazolone, 4-(1,1-dimethylethyl)-2-phenyl-
CAS 71953-55-4C13H15NO2
(4S)-4-Methyl-2-phenyl-5(4H)-oxazolone chemical structure, C10H9NO2, CAS 71963-72-9
(4S)-4-Methyl-2-phenyl-5(4H)-oxazolone
CAS 71963-72-9C10H9NO2
2-(p-Tolyl)oxazol-5(4H)-one chemical structure, C10H9NO2, CAS 75152-18-0
2-(p-Tolyl)oxazol-5(4H)-one
CAS 75152-18-0C10H9NO2
4-Methyl-2-phenyl-4-propan-2-yl-1,3-oxazol-5-one chemical structure, C13H15NO2, CAS 169566-78-3
4-Methyl-2-phenyl-4-propan-2-yl-1,3-oxazol-5-one
CAS 169566-78-3C13H15NO2
1,1-Dimethylethyl 4,5-dihydro-5-oxo-2-phenyl-4-oxazolepropanoate chemical structure, C16H19NO4, CAS 161574-32-9
1,1-Dimethylethyl 4,5-dihydro-5-oxo-2-phenyl-4-oxazolepropanoate
CAS 161574-32-9C16H19NO4
4-(Iodomethyl)-4-methyl-2-phenyloxazol-5(4H)-one chemical structure, C11H10INO2, CAS 177762-91-3
4-(Iodomethyl)-4-methyl-2-phenyloxazol-5(4H)-one
CAS 177762-91-3C11H10INO2
5(4H)-Oxazolone, 2-(4-chlorophenyl)- chemical structure, C9H6ClNO2, CAS 22887-53-2
5(4H)-Oxazolone, 2-(4-chlorophenyl)-
CAS 22887-53-2C9H6ClNO2
2-(4-Methoxyphenyl)-4-methyloxazol-5(4H)-one chemical structure, C11H11NO3, CAS 85380-77-4
2-(4-Methoxyphenyl)-4-methyloxazol-5(4H)-one
CAS 85380-77-4C11H11NO3
5(4H)-Oxazolone, 4,4-dimethyl-2-(2,4,6-trimethylphenyl)- chemical structure, C14H17NO2, CAS 86951-77-1
5(4H)-Oxazolone, 4,4-dimethyl-2-(2,4,6-trimethylphenyl)-
CAS 86951-77-1C14H17NO2
2-Phenyl-4-propanoyl-1,3-oxazol-5(4H)-one chemical structure, C12H11NO3, CAS 85094-77-5
2-Phenyl-4-propanoyl-1,3-oxazol-5(4H)-one
CAS 85094-77-5C12H11NO3
5(4H)-Oxazolone, 4-methyl-2-(4-nitrophenyl)- chemical structure, C10H8N2O4, CAS 82387-87-9
5(4H)-Oxazolone, 4-methyl-2-(4-nitrophenyl)-
CAS 82387-87-9C10H8N2O4
5(4H)-Oxazolone, 4-methyl-2-phenyl-4-(2-propen-1-yl)- chemical structure, C13H13NO2, CAS 95885-61-3
5(4H)-Oxazolone, 4-methyl-2-phenyl-4-(2-propen-1-yl)-
CAS 95885-61-3C13H13NO2
4-Butanoyl-2-phenyl-1,3-oxazol-5(4H)-one chemical structure, C13H13NO3, CAS 90127-56-3
4-Butanoyl-2-phenyl-1,3-oxazol-5(4H)-one
CAS 90127-56-3C13H13NO3
4-Ethyl-2-phenyloxazol-5(4H)-one chemical structure, C11H11NO2, CAS 36974-43-3
4-Ethyl-2-phenyloxazol-5(4H)-one
CAS 36974-43-3C11H11NO2
4-Oxazolepropanenitrile, 2-(4-chlorophenyl)-4,5-dihydro-4-(1-methylethyl)-5-oxo- chemical structure, C15H15ClN2O2, CAS 86435-52-1
4-Oxazolepropanenitrile, 2-(4-chlorophenyl)-4,5-dihydro-4-(1-methylethyl)-5-oxo-
CAS 86435-52-1C15H15ClN2O2
4-Oxazolepropanenitrile, 2-(2,4-dichlorophenyl)-4,5-dihydro-4-methyl-5-oxo- chemical structure, C13H10Cl2N2O2, CAS 86435-53-2
4-Oxazolepropanenitrile, 2-(2,4-dichlorophenyl)-4,5-dihydro-4-methyl-5-oxo-
CAS 86435-53-2C13H10Cl2N2O2
4-Oxazolepropanenitrile, 4,5-dihydro-4-methyl-2-(4-nitrophenyl)-5-oxo- chemical structure, C13H11N3O4, CAS 86435-54-3
4-Oxazolepropanenitrile, 4,5-dihydro-4-methyl-2-(4-nitrophenyl)-5-oxo-
CAS 86435-54-3C13H11N3O4
4-Oxazolepropanenitrile, 2-(2-chlorophenyl)-4,5-dihydro-4-methyl-5-oxo- chemical structure, C13H11ClN2O2, CAS 86435-55-4
4-Oxazolepropanenitrile, 2-(2-chlorophenyl)-4,5-dihydro-4-methyl-5-oxo-
CAS 86435-55-4C13H11ClN2O2
4-Oxazolepropanenitrile, 4,5-dihydro-4-methyl-2-(4-methylphenyl)-5-oxo- chemical structure, C14H14N2O2, CAS 86435-56-5
4-Oxazolepropanenitrile, 4,5-dihydro-4-methyl-2-(4-methylphenyl)-5-oxo-
CAS 86435-56-5C14H14N2O2