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Murcko scaffold

2-(Piperazin-1-yl)-1,3,5-triazine scaffold

51 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
51
With full pages
4
Scaffold SMILES

c1ncnc(N2CCNCC2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Piperazin-1-yl)-1,3,5-triazine page
Murcko scaffold c1ncnc(N2CCNCC2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 51 chemicals

s-Triazine, 2,4-diamino-6-(1-piperazinyl)- chemical structure, C7H13N7, CAS 21840-23-3
s-Triazine, 2,4-diamino-6-(1-piperazinyl)-
CAS 21840-23-3C7H13N7
2-(Piperazin-1-yl)-1,3,5-triazine chemical structure, C7H11N5, CAS 59215-44-0
2-(Piperazin-1-yl)-1,3,5-triazine
CAS 59215-44-0C7H11N5
1,3,5-Triazin-2-amine, 4-(4-methyl-1-piperazinyl)-6-(trifluoromethyl)- chemical structure, C9H13F3N6, CAS 58892-42-5
1,3,5-Triazin-2-amine, 4-(4-methyl-1-piperazinyl)-6-(trifluoromethyl)-
CAS 58892-42-5C9H13F3N6
1-Piperazineethanol, 4-(4-amino-6-trifluoromethyl-2-s-triazinyl)- chemical structure, C10H15F3N6O, CAS 58892-43-6
1-Piperazineethanol, 4-(4-amino-6-trifluoromethyl-2-s-triazinyl)-
CAS 58892-43-6C10H15F3N6O
s-Triazine, 2-hydrazino-4-piperazinyl-6-(trifluoromethyl)- chemical structure, C8H12F3N7, CAS 58892-45-8
s-Triazine, 2-hydrazino-4-piperazinyl-6-(trifluoromethyl)-
CAS 58892-45-8C8H12F3N7
Piperazine, 1-acetyl-4-(4-hydrazino-6-(trifluoromethyl)-1,3,5-triazin-2-yl)- chemical structure, C10H14F3N7O, CAS 58892-46-9
Piperazine, 1-acetyl-4-(4-hydrazino-6-(trifluoromethyl)-1,3,5-triazin-2-yl)-
CAS 58892-46-9C10H14F3N7O
s-Triazine, 2-hydrazino-4-(4-methylpiperazin-1-yl)-6-trifluoromethyl- chemical structure, C9H14F3N7, CAS 58892-47-0
s-Triazine, 2-hydrazino-4-(4-methylpiperazin-1-yl)-6-trifluoromethyl-
CAS 58892-47-0C9H14F3N7
1,3,5-Triazin-2-amine, N,N-dimethyl-4-(4-methyl-1-piperazinyl)-6-(trifluoromethyl)- chemical structure, C11H17F3N6, CAS 58892-52-7
1,3,5-Triazin-2-amine, N,N-dimethyl-4-(4-methyl-1-piperazinyl)-6-(trifluoromethyl)-
CAS 58892-52-7C11H17F3N6
tert-Butyl 4-(4-amino-1,3,5-triazin-2-yl)piperazine-1-carboxylate chemical structure, C12H20N6O2, CAS 212264-36-3
tert-Butyl 4-(4-amino-1,3,5-triazin-2-yl)piperazine-1-carboxylate
CAS 212264-36-3C12H20N6O2
tert-Butyl 4-(4,6-dichloro-1,3,5-triazin-2-yl)piperazine-1-carboxylate chemical structure, C12H17Cl2N5O2, CAS 271592-49-5
tert-Butyl 4-(4,6-dichloro-1,3,5-triazin-2-yl)piperazine-1-carboxylate
CAS 271592-49-5C12H17Cl2N5O2
4,6-Diethoxy-2-piperazino-1,3,5-triazine chemical structure, C11H19N5O2, CAS 83774-22-5
4,6-Diethoxy-2-piperazino-1,3,5-triazine
CAS 83774-22-5C11H19N5O2
2,4-Dichloro-6-(piperazin-1-yl)-1,3,5-triazine chemical structure, C7H9Cl2N5, CAS 111373-07-0
2,4-Dichloro-6-(piperazin-1-yl)-1,3,5-triazine
CAS 111373-07-0C7H9Cl2N5
tert-Butyl 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)piperazine-1-carboxylate chemical structure, C14H23N5O4, CAS 948825-19-2
tert-Butyl 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)piperazine-1-carboxylate
CAS 948825-19-2C14H23N5O4
2-(4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)piperazin-1-yl)ethanol hydrochloride chemical structure, C11H20ClN5O3, CAS 1177093-22-9
2-(4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)piperazin-1-yl)ethanol hydrochloride
CAS 1177093-22-9C11H20ClN5O3
2-[4-(4-Amino-6-chloro-1,3,5-triazin-2-yl)-1-piperazinyl]-1-ethanol chemical structure, C9H15ClN6O, CAS 1220016-94-3
2-[4-(4-Amino-6-chloro-1,3,5-triazin-2-yl)-1-piperazinyl]-1-ethanol
CAS 1220016-94-3C9H15ClN6O
4-Chloro-6-(4-methyl-1-piperazinyl)-1,3,5-triazin-2-amine chemical structure, C8H13ClN6, CAS 1220038-40-3
4-Chloro-6-(4-methyl-1-piperazinyl)-1,3,5-triazin-2-amine
CAS 1220038-40-3C8H13ClN6
2-Chloro-4-(piperazin-1-yl)-1,3,5-triazine chemical structure, C7H10ClN5, CAS 2230807-22-2
2-Chloro-4-(piperazin-1-yl)-1,3,5-triazine
CAS 2230807-22-2C7H10ClN5
Dimethyl-(4-piperazin-1-yl-[1,3,5]triazin-2-yl)-amine chemical structure, C9H16N6, CAS 845617-08-5
Dimethyl-(4-piperazin-1-yl-[1,3,5]triazin-2-yl)-amine
CAS 845617-08-5C9H16N6
2,4-Dimethoxy-6-(piperazin-1-yl)-1,3,5-triazine chemical structure, C9H15N5O2, CAS 59215-46-2
2,4-Dimethoxy-6-(piperazin-1-yl)-1,3,5-triazine
CAS 59215-46-2C9H15N5O2
2-Chloro-4-(piperazin-1-yl)-6-propoxy-1,3,5-triazine chemical structure, C10H16ClN5O, CAS 1378259-46-1
2-Chloro-4-(piperazin-1-yl)-6-propoxy-1,3,5-triazine
CAS 1378259-46-1C10H16ClN5O
2-Chloro-4-ethoxy-6-(piperazin-1-yl)-1,3,5-triazine chemical structure, C9H14ClN5O, CAS 1341163-95-8
2-Chloro-4-ethoxy-6-(piperazin-1-yl)-1,3,5-triazine
CAS 1341163-95-8C9H14ClN5O
2-Methoxy-4-piperazin-1-yl-[1,3,5]triazine chemical structure, C8H13N5O, CAS 59215-45-1
2-Methoxy-4-piperazin-1-yl-[1,3,5]triazine
CAS 59215-45-1C8H13N5O
2-Butyl-4-hydrazinyl-6-(piperazin-1-yl)-1,3,5-triazine chemical structure, C11H21N7, CAS 61082-40-4
2-Butyl-4-hydrazinyl-6-(piperazin-1-yl)-1,3,5-triazine
CAS 61082-40-4C11H21N7
2-Hydrazinyl-4-methyl-6-(piperazin-1-yl)-1,3,5-triazine chemical structure, C8H15N7, CAS 61082-39-1
2-Hydrazinyl-4-methyl-6-(piperazin-1-yl)-1,3,5-triazine
CAS 61082-39-1C8H15N7