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Murcko scaffold

1,2,4-Triazolo(1,5-c)pyrimidine scaffold

80 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 9
Chemicals: 80
With full pages: 6

Scaffold SMILES

c1cc2ncnn2cn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1,2,4-Triazolo(1,5-c)pyrimidine page

Murcko scaffold c1cc2ncnn2cn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 80 of 80 chemicals

5,7-Dimethyl[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonyl chloride chemical structure, C7H7ClN4O2S, CAS 112729-27-8

5,7-Dimethyl[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonyl chloride

CAS 112729-27-8C₇H₇ClN₄O₂S

5-Hydrazino-2-(trifluoromethyl)[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C6H5F3N6, CAS 877402-87-4

5-Hydrazino-2-(trifluoromethyl)[1,2,4]triazolo[1,5-c]pyrimidine

CAS 877402-87-4C₆H₅F₃N₆

7-Chloro-5-methylsulfanyl-[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C6H5ClN4S, CAS 883738-14-5

7-Chloro-5-methylsulfanyl-[1,2,4]triazolo[1,5-c]pyrimidine

CAS 883738-14-5C₆H₅ClN₄S

2-(Chloromethyl)-5,8-dimethyl-[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C8H9ClN4, CAS 1351515-93-9

2-(Chloromethyl)-5,8-dimethyl-[1,2,4]triazolo[1,5-c]pyrimidine

CAS 1351515-93-9C₈H₉ClN₄

8-Fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-amine chemical structure, C6H6FN5O, CAS 219715-60-3

8-Fluoro-5-methoxy-[1,2,4]triazolo[1,5-c]pyrimidin-2-amine

CAS 219715-60-3C₆H₆FN₅O

2-Bromo-7-methyl-5-propyl[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C9H11BrN4, CAS 1792-18-3

2-Bromo-7-methyl-5-propyl[1,2,4]triazolo[1,5-c]pyrimidine

CAS 1792-18-3C₉H₁₁BrN₄

5-Chloro-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-C]pyrimidine chemical structure, C6H2ClF3N4, CAS 877402-89-6

5-Chloro-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-C]pyrimidine

CAS 877402-89-6C₆H₂ClF₃N₄

Ethyl 7-chloro-[1,2,4]triazolo[1,5-c]pyrimidine-2-carboxylate chemical structure, C8H7ClN4O2, CAS 1375474-57-9

Ethyl 7-chloro-[1,2,4]triazolo[1,5-c]pyrimidine-2-carboxylate

CAS 1375474-57-9C₈H₇ClN₄O₂

8-Bromo-5-chloro-[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C5H2BrClN4, CAS 1367774-82-0

8-Bromo-5-chloro-[1,2,4]triazolo[1,5-c]pyrimidine

CAS 1367774-82-0C₅H₂BrClN₄

5-Chloro-[1,2,4]triazolo[1,5-c]pyrimidin-8-amine chemical structure, C5H4ClN5, CAS 1367917-04-1

5-Chloro-[1,2,4]triazolo[1,5-c]pyrimidin-8-amine

CAS 1367917-04-1C₅H₄ClN₅

[1,2,4]Triazolo[1,5-c]pyrimidin-7-ylmethanamine chemical structure, C6H7N5, CAS 1464891-97-1

[1,2,4]Triazolo[1,5-c]pyrimidin-7-ylmethanamine

CAS 1464891-97-1C₆H₇N₅

2-Chloro-[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C5H3ClN4, CAS 1784519-03-4

2-Chloro-[1,2,4]triazolo[1,5-c]pyrimidine

CAS 1784519-03-4C₅H₃ClN₄

2-Chloro-7-methyl-[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C6H5ClN4, CAS 1784871-17-5

2-Chloro-7-methyl-[1,2,4]triazolo[1,5-c]pyrimidine

CAS 1784871-17-5C₆H₅ClN₄

2-Chloro-5-methyl-[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C6H5ClN4, CAS 1785622-14-1

2-Chloro-5-methyl-[1,2,4]triazolo[1,5-c]pyrimidine

CAS 1785622-14-1C₆H₅ClN₄

2-Bromo-[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C5H3BrN4, CAS 1783343-16-7

2-Bromo-[1,2,4]triazolo[1,5-c]pyrimidine

CAS 1783343-16-7C₅H₃BrN₄

5-Methyl[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonyl chloride chemical structure, C6H5ClN4O2S, CAS 146941-73-3

5-Methyl[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonyl chloride

CAS 146941-73-3C₆H₅ClN₄O₂S

7-Chloro-2-(chloromethyl)-5,8-dimethyl[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C8H8Cl2N4, CAS 1201687-90-2

7-Chloro-2-(chloromethyl)-5,8-dimethyl[1,2,4]triazolo[1,5-c]pyrimidine

CAS 1201687-90-2C₈H₈Cl₂N₄

5-Ethoxy-7-fluoro-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide chemical structure, C7H8FN5O3S, CAS 292088-82-5

5-Ethoxy-7-fluoro-[1,2,4]triazolo[1,5-c]pyrimidine-2-sulfonamide

CAS 292088-82-5C₇H₈FN₅O₃S

5,7-Dichloro-2-methyl[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C6H4Cl2N4, CAS 1379309-26-8

5,7-Dichloro-2-methyl[1,2,4]triazolo[1,5-c]pyrimidine

CAS 1379309-26-8C₆H₄Cl₂N₄

5-Chloro[1,2,4]triazolo[1,5-c]pyrimidin-2-amine chemical structure, C5H4ClN5, CAS 1980044-44-7

5-Chloro[1,2,4]triazolo[1,5-c]pyrimidin-2-amine

CAS 1980044-44-7C₅H₄ClN₅

5-Chloro-2-iodo[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C5H2ClIN4, CAS 1980050-24-5

5-Chloro-2-iodo[1,2,4]triazolo[1,5-c]pyrimidine

CAS 1980050-24-5C₅H₂ClIN₄

7-Chloro-[1,2,4]triazolo[1,5-C]pyrimidine-5-amine chemical structure, C5H4ClN5, CAS 2246426-83-3

7-Chloro-[1,2,4]triazolo[1,5-C]pyrimidine-5-amine

CAS 2246426-83-3C₅H₄ClN₅

5-Chloro-8-fluoro-[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C5H2ClFN4, CAS 2096987-07-2

5-Chloro-8-fluoro-[1,2,4]triazolo[1,5-c]pyrimidine

CAS 2096987-07-2C₅H₂ClFN₄

7-Chloro-2-iodo-5-methyl-[1,2,4]triazolo[1,5-c]pyrimidine chemical structure, C6H4ClIN4, CAS 2095412-40-9

7-Chloro-2-iodo-5-methyl-[1,2,4]triazolo[1,5-c]pyrimidine

CAS 2095412-40-9C₆H₄ClIN₄