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Murcko scaffold

2-(2'-Thienyl)pyridine scaffold

239 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
239
With full pages
21
Scaffold SMILES

c1ccc(-c2cccs2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(2'-Thienyl)pyridine page
Murcko scaffold c1ccc(-c2cccs2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 239 chemicals

2-(2'-Thienyl)pyridine chemical structure, C9H7NS, CAS 3319-99-1
2-(2'-Thienyl)pyridine
CAS 3319-99-1C9H7NS
4-Picoline, 2-chloro-6-(2-thienyl)-alpha,alpha,alpha-trifluoro- chemical structure, C10H5ClF3NS, CAS 22123-15-5
4-Picoline, 2-chloro-6-(2-thienyl)-alpha,alpha,alpha-trifluoro-
CAS 22123-15-5C10H5ClF3NS
5-(Pyridin-2-yl)thiophene-2-carbaldehyde chemical structure, C10H7NOS, CAS 132706-12-8
5-(Pyridin-2-yl)thiophene-2-carbaldehyde
CAS 132706-12-8C10H7NOS
2-[(Diethoxyphosphorothioyl)oxy]-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile chemical structure, C15H14F3N2O3PS2, CAS 286435-85-6
2-[(Diethoxyphosphorothioyl)oxy]-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile
CAS 286435-85-6C15H14F3N2O3PS2
2-{[3-Cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetic acid chemical structure, C13H7F3N2O2S2, CAS 330645-53-9
2-{[3-Cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetic acid
CAS 330645-53-9C13H7F3N2O2S2
2-Ethylsulfanyl-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile chemical structure, C13H9F3N2S2, CAS 339165-66-1
2-Ethylsulfanyl-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile
CAS 339165-66-1C13H9F3N2S2
5-(Pyridin-2-yl)thiophene-2-carboxylic acid chemical structure, C10H7NO2S, CAS 119082-97-2
5-(Pyridin-2-yl)thiophene-2-carboxylic acid
CAS 119082-97-2C10H7NO2S
2-(5-Bromo-2-thienyl)pyridine chemical structure, C9H6BrNS, CAS 123784-07-6
2-(5-Bromo-2-thienyl)pyridine
CAS 123784-07-6C9H6BrNS
2-((3-Cyano-6-(2-thienyl)-4-(trifluoromethyl)-2-pyridinyl)thio)acetamide chemical structure, C13H8F3N3OS2, CAS 299198-19-9
2-((3-Cyano-6-(2-thienyl)-4-(trifluoromethyl)-2-pyridinyl)thio)acetamide
CAS 299198-19-9C13H8F3N3OS2
2-(Methylsulfonyl)-6-(2-thienyl)nicotinonitrile chemical structure, C11H8N2O2S2, CAS 625367-78-4
2-(Methylsulfonyl)-6-(2-thienyl)nicotinonitrile
CAS 625367-78-4C11H8N2O2S2
2-Chloro-6-(thiophen-2-yl)nicotinic acid chemical structure, C10H6ClNO2S, CAS 462066-76-8
2-Chloro-6-(thiophen-2-yl)nicotinic acid
CAS 462066-76-8C10H6ClNO2S
2-(Isopentylsulfanyl)-6-(2-thienyl)nicotinonitrile chemical structure, C15H16N2S2, CAS 445383-93-7
2-(Isopentylsulfanyl)-6-(2-thienyl)nicotinonitrile
CAS 445383-93-7C15H16N2S2
Isopropyl {[3-cyano-6-(2-thienyl)-4-(trifluoromethyl)-2-pyridinyl]sulfanyl}acetate chemical structure, C16H13F3N2O2S2, CAS 445266-37-5
Isopropyl {[3-cyano-6-(2-thienyl)-4-(trifluoromethyl)-2-pyridinyl]sulfanyl}acetate
CAS 445266-37-5C16H13F3N2O2S2
Methyl 4-[3-cyano-6-thiophen-2-yl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl-3-oxobutanoate chemical structure, C16H11F3N2O3S2, CAS 445266-57-9
Methyl 4-[3-cyano-6-thiophen-2-yl-4-(trifluoromethyl)pyridin-2-yl]sulfanyl-3-oxobutanoate
CAS 445266-57-9C16H11F3N2O3S2
Ethyl ((3-cyano-6-(2-thienyl)-4-(trifluoromethyl)-2-pyridinyl)thio)acetate chemical structure, C15H11F3N2O2S2, CAS 299198-22-4
Ethyl ((3-cyano-6-(2-thienyl)-4-(trifluoromethyl)-2-pyridinyl)thio)acetate
CAS 299198-22-4C15H11F3N2O2S2
2-((3-Cyano-6-(thiophen-2-yl)pyridin-2-yl)thio)acetic acid chemical structure, C12H8N2O2S2, CAS 340807-55-8
2-((3-Cyano-6-(thiophen-2-yl)pyridin-2-yl)thio)acetic acid
CAS 340807-55-8C12H8N2O2S2
2-(Butylsulfanyl)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile chemical structure, C15H13F3N2S2, CAS 340816-55-9
2-(Butylsulfanyl)-6-(2-thienyl)-4-(trifluoromethyl)nicotinonitrile
CAS 340816-55-9C15H13F3N2S2
2-[(Cyanomethyl)sulfanyl]-6-(2-thienyl)nicotinonitrile chemical structure, C12H7N3S2, CAS 313380-32-4
2-[(Cyanomethyl)sulfanyl]-6-(2-thienyl)nicotinonitrile
CAS 313380-32-4C12H7N3S2
2-(2-Cyanoethylsulfanyl)-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile chemical structure, C14H8F3N3S2, CAS 445266-52-4
2-(2-Cyanoethylsulfanyl)-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile
CAS 445266-52-4C14H8F3N3S2
Ethyl 4-[3-cyano-6-thiophen-2-yl-4-(trifluoromethyl)pyridin-2-yl]sulfanylbutanoate chemical structure, C17H15F3N2O2S2, CAS 625376-89-8
Ethyl 4-[3-cyano-6-thiophen-2-yl-4-(trifluoromethyl)pyridin-2-yl]sulfanylbutanoate
CAS 625376-89-8C17H15F3N2O2S2
5-(3-Aminopyridin-2-yl)thiophene-2-carboxylic acid chemical structure, C10H8N2O2S, CAS 887201-18-5
5-(3-Aminopyridin-2-yl)thiophene-2-carboxylic acid
CAS 887201-18-5C10H8N2O2S
2-(Cyanomethylsulfanyl)-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile chemical structure, C13H6F3N3S2, CAS 330220-40-1
2-(Cyanomethylsulfanyl)-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile
CAS 330220-40-1C13H6F3N3S2
2-(2-Ethylsulfanylethylsulfanyl)-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile chemical structure, C15H13F3N2S3, CAS 296798-71-5
2-(2-Ethylsulfanylethylsulfanyl)-6-thiophen-2-yl-4-(trifluoromethyl)pyridine-3-carbonitrile
CAS 296798-71-5C15H13F3N2S3
2-(Propylthio)-6-(thiophen-2-yl)-4-(trifluoromethyl)nicotinonitrile chemical structure, C14H11F3N2S2, CAS 617696-19-2
2-(Propylthio)-6-(thiophen-2-yl)-4-(trifluoromethyl)nicotinonitrile
CAS 617696-19-2C14H11F3N2S2