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Murcko scaffold

2-(2'-Thienyl)pyridine scaffold

239 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
239
With full pages
2
Scaffold SMILES

c1ccc(-c2cccs2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(2'-Thienyl)pyridine page
Murcko scaffold c1ccc(-c2cccs2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 239 chemicals

2-(Thiophen-2-yl)pyridin-3-amine chemical structure, C9H8N2S, CAS 886507-53-5
2-(Thiophen-2-yl)pyridin-3-amine
CAS 886507-53-5C9H8N2S
2-[5-(1,1-Dimethylethoxy)-2-thienyl]pyridine chemical structure, C13H15NOS, CAS 169050-06-0
2-[5-(1,1-Dimethylethoxy)-2-thienyl]pyridine
CAS 169050-06-0C13H15NOS
6-(Thiophen-2-yl)pyridine-2-carbaldehyde chemical structure, C10H7NOS, CAS 208111-00-6
6-(Thiophen-2-yl)pyridine-2-carbaldehyde
CAS 208111-00-6C10H7NOS
2-Bromo-6-(thiophen-2-yl)pyridine chemical structure, C9H6BrNS, CAS 220196-07-6
2-Bromo-6-(thiophen-2-yl)pyridine
CAS 220196-07-6C9H6BrNS
2-(5-Methyl-2-pyridyl)thiophene chemical structure, C10H9NS, CAS 56421-68-2
2-(5-Methyl-2-pyridyl)thiophene
CAS 56421-68-2C10H9NS
6-Thien-2-ylnicotinonitrile chemical structure, C10H6N2S, CAS 619334-36-0
6-Thien-2-ylnicotinonitrile
CAS 619334-36-0C10H6N2S
6-(5-Bromo-2-thienyl)-3-pyridinecarbonitrile chemical structure, C10H5BrN2S, CAS 619334-37-1
6-(5-Bromo-2-thienyl)-3-pyridinecarbonitrile
CAS 619334-37-1C10H5BrN2S
Ethyl 2-methyl-6-(thiophen-2-yl)-4-(trifluoromethyl)nicotinate chemical structure, C14H12F3NO2S, CAS 200879-81-8
Ethyl 2-methyl-6-(thiophen-2-yl)-4-(trifluoromethyl)nicotinate
CAS 200879-81-8C14H12F3NO2S
5-Bromo-2-(5-bromo-2-thienyl)pyridine chemical structure, C9H5Br2NS, CAS 136902-53-9
5-Bromo-2-(5-bromo-2-thienyl)pyridine
CAS 136902-53-9C9H5Br2NS
5-Chloro-2-(thiophen-2-yl)pyridine chemical structure, C9H6ClNS, CAS 56421-70-6
5-Chloro-2-(thiophen-2-yl)pyridine
CAS 56421-70-6C9H6ClNS
2-[3-(Trimethylsilyl)thiophen-2-yl]pyridine chemical structure, C12H15NSSi, CAS 51459-68-8
2-[3-(Trimethylsilyl)thiophen-2-yl]pyridine
CAS 51459-68-8C12H15NSSi
5-Bromo-2-(2-thienyl)pyridine chemical structure, C9H6BrNS, CAS 91891-74-6
5-Bromo-2-(2-thienyl)pyridine
CAS 91891-74-6C9H6BrNS
3-Nitro-6-(thiophen-2-yl)pyridin-2-amine chemical structure, C9H7N3O2S, CAS 102266-16-0
3-Nitro-6-(thiophen-2-yl)pyridin-2-amine
CAS 102266-16-0C9H7N3O2S
2-(4-Bromothiophen-2-yl)pyridine chemical structure, C9H6BrNS, CAS 123784-08-7
2-(4-Bromothiophen-2-yl)pyridine
CAS 123784-08-7C9H6BrNS
2-(5-Chloro-2-thienyl)pyridine chemical structure, C9H6ClNS, CAS 123784-09-8
2-(5-Chloro-2-thienyl)pyridine
CAS 123784-09-8C9H6ClNS
1-(5-(Pyridin-2-yl)thiophen-2-yl)ethanone chemical structure, C11H9NOS, CAS 123784-11-2
1-(5-(Pyridin-2-yl)thiophen-2-yl)ethanone
CAS 123784-11-2C11H9NOS
2-(5-Ethynylthien-2-yl)pyridine chemical structure, C11H7NS, CAS 132464-90-5
2-(5-Ethynylthien-2-yl)pyridine
CAS 132464-90-5C11H7NS
6-(Thiophen-2-yl)pyridine-3-carboxylic acid chemical structure, C10H7NO2S, CAS 179408-54-9
6-(Thiophen-2-yl)pyridine-3-carboxylic acid
CAS 179408-54-9C10H7NO2S
(6-Thien-2-ylpyrid-3-yl)methanol chemical structure, C10H9NOS, CAS 198078-57-8
(6-Thien-2-ylpyrid-3-yl)methanol
CAS 198078-57-8C10H9NOS
2-(5-Methylthiophen-2-yl)pyridine chemical structure, C10H9NS, CAS 139003-60-4
2-(5-Methylthiophen-2-yl)pyridine
CAS 139003-60-4C10H9NS
2-(5-Ethyl-2-thienyl)pyridine chemical structure, C11H11NS, CAS 139003-61-5
2-(5-Ethyl-2-thienyl)pyridine
CAS 139003-61-5C11H11NS
2-{[3-Cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-methylacetamide chemical structure, C14H10F3N3OS2, CAS 905772-99-8
2-{[3-Cyano-6-(thiophen-2-yl)-4-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-methylacetamide
CAS 905772-99-8C14H10F3N3OS2
2-Chloro-6-thiophen-2-yl-nicotinonitrile chemical structure, C10H5ClN2S, CAS 946385-78-0
2-Chloro-6-thiophen-2-yl-nicotinonitrile
CAS 946385-78-0C10H5ClN2S
2-((2-Methoxyethyl)thio)-6-(thiophen-2-yl)-4-(trifluoromethyl)nicotinonitrile chemical structure, C14H11F3N2OS2, CAS 905772-97-6
2-((2-Methoxyethyl)thio)-6-(thiophen-2-yl)-4-(trifluoromethyl)nicotinonitrile
CAS 905772-97-6C14H11F3N2OS2