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Murcko scaffold

Ring system with 2 rings and 13 atoms

53 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
53
With full pages
6
Scaffold SMILES

C=C1N=C(c2ccccc2)OC1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C=C1N=C(c2ccccc2)OC1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 53 of 53 chemicals

2-Phenyl-4-(3,3,3-trifluoro-2-methylpropylidene)-1,3-oxazol-5(4H)-one chemical structure, C13H10F3NO2
2-Phenyl-4-(3,3,3-trifluoro-2-methylpropylidene)-1,3-oxazol-5(4H)-one
C13H10F3NO2
5(4H)-Oxazolone, 4-heptylidene-2-phenyl- chemical structure, C16H19NO2, CAS 101287-10-9
5(4H)-Oxazolone, 4-heptylidene-2-phenyl-
CAS 101287-10-9C16H19NO2
4-[Chloro(dimethylamino)methylidene]-2-phenyl-1,3-oxazol-5(4H)-one chemical structure, C12H11ClN2O2, CAS 61767-44-0
4-[Chloro(dimethylamino)methylidene]-2-phenyl-1,3-oxazol-5(4H)-one
CAS 61767-44-0C12H11ClN2O2
(E)-4-(Chloromethylene)-2-phenyloxazol-5(4H)-one chemical structure, C10H6ClNO2, CAS 89363-85-9
(E)-4-(Chloromethylene)-2-phenyloxazol-5(4H)-one
CAS 89363-85-9C10H6ClNO2
4-(Chloro(dimethylamino)methylene)-2-phenyloxazol-5(4H)-one chemical structure, C12H11ClN2O2
4-(Chloro(dimethylamino)methylene)-2-phenyloxazol-5(4H)-one
C12H11ClN2O2