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Murcko scaffold

Ring system with 2 rings and 16 atoms

20 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
20
With full pages
3
Scaffold SMILES

O=C(Cc1n[nH]c(=S)[nH]1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1n[nH]c(=S)[nH]1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

N-(3,4-Dichlorophenyl)-2-(4-methyl-5-sulfanyl-4H-1,2,4-triazol-3-yl)acetamide chemical structure, C11H10Cl2N4OS, CAS 708219-00-5
N-(3,4-Dichlorophenyl)-2-(4-methyl-5-sulfanyl-4H-1,2,4-triazol-3-yl)acetamide
CAS 708219-00-5C11H10Cl2N4OS
2-(5-Mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-N-p-tolyl-acetamide chemical structure, C12H14N4OS, CAS 701273-12-3
2-(5-Mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-N-p-tolyl-acetamide
CAS 701273-12-3C12H14N4OS
2-(4-Ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-p-tolyl-acetamide chemical structure, C13H16N4OS, CAS 756120-52-2
2-(4-Ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-p-tolyl-acetamide
CAS 756120-52-2C13H16N4OS
N-(3-Methoxyphenyl)-2-[4-(prop-2-en-1-yl)-5-sulfanyl-4H-1,2,4-triazol-3-yl]acetamide chemical structure, C14H16N4O2S, CAS 792941-65-2
N-(3-Methoxyphenyl)-2-[4-(prop-2-en-1-yl)-5-sulfanyl-4H-1,2,4-triazol-3-yl]acetamide
CAS 792941-65-2C14H16N4O2S
N-(2-Chloro-phenyl)-2-(4-ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-acetamide chemical structure, C12H13ClN4OS, CAS 879610-06-7
N-(2-Chloro-phenyl)-2-(4-ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-acetamide
CAS 879610-06-7C12H13ClN4OS
N-(3-Chloro-4-methyl-phenyl)-2-(5-mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-acetamide chemical structure, C12H13ClN4OS, CAS 879612-22-3
N-(3-Chloro-4-methyl-phenyl)-2-(5-mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-acetamide
CAS 879612-22-3C12H13ClN4OS
N-(2-Fluoro-phenyl)-2-(5-mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-acetamide chemical structure, C11H11FN4OS, CAS 792944-57-1
N-(2-Fluoro-phenyl)-2-(5-mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-acetamide
CAS 792944-57-1C11H11FN4OS
2-(4-Ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-(2-fluoro-phenyl)-acetamide chemical structure, C12H13FN4OS, CAS 792944-58-2
2-(4-Ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-(2-fluoro-phenyl)-acetamide
CAS 792944-58-2C12H13FN4OS
2-(4-Allyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-(2-fluoro-phenyl)-acetamide chemical structure, C13H13FN4OS, CAS 792944-59-3
2-(4-Allyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-(2-fluoro-phenyl)-acetamide
CAS 792944-59-3C13H13FN4OS
2-(5-Mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-N-o-tolyl-acetamide chemical structure, C12H14N4OS, CAS 792944-60-6
2-(5-Mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-N-o-tolyl-acetamide
CAS 792944-60-6C12H14N4OS
2-(5-Mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-N-(4-methoxy-phenyl)-acetamide chemical structure, C12H14N4O2S, CAS 792944-61-7
2-(5-Mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-N-(4-methoxy-phenyl)-acetamide
CAS 792944-61-7C12H14N4O2S
2-(5-Mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-N-(2-methoxy-phenyl)-acetamide chemical structure, C12H14N4O2S, CAS 792944-62-8
2-(5-Mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-N-(2-methoxy-phenyl)-acetamide
CAS 792944-62-8C12H14N4O2S
N-(4-Fluoro-phenyl)-2-(5-mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-acetamide chemical structure, C11H11FN4OS, CAS 792944-66-2
N-(4-Fluoro-phenyl)-2-(5-mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-acetamide
CAS 792944-66-2C11H11FN4OS
2-(4-Ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-o-tolyl-acetamide chemical structure, C13H16N4OS, CAS 792944-67-3
2-(4-Ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-o-tolyl-acetamide
CAS 792944-67-3C13H16N4OS
2-(4-Ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-(4-methoxy-phenyl)-acetamide chemical structure, C13H16N4O2S, CAS 792944-68-4
2-(4-Ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-(4-methoxy-phenyl)-acetamide
CAS 792944-68-4C13H16N4O2S
2-(4-Ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-(2-methoxy-phenyl)-acetamide chemical structure, C13H16N4O2S, CAS 792944-69-5
2-(4-Ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-(2-methoxy-phenyl)-acetamide
CAS 792944-69-5C13H16N4O2S
2-(4-Ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-(4-fluoro-phenyl)-acetamide chemical structure, C12H13FN4OS, CAS 792944-74-2
2-(4-Ethyl-5-mercapto-4H-[1,2,4]triazol-3-yl)-N-(4-fluoro-phenyl)-acetamide
CAS 792944-74-2C12H13FN4OS
N-(2,4-Dimethylphenyl)-2-(4-ethyl-5-sulfanyl-4H-1,2,4-triazol-3-yl)acetamide chemical structure, C14H18N4OS, CAS 924969-62-0
N-(2,4-Dimethylphenyl)-2-(4-ethyl-5-sulfanyl-4H-1,2,4-triazol-3-yl)acetamide
CAS 924969-62-0C14H18N4OS
N-(2,5-Dimethyl-phenyl)-2-(5-mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-acetamide chemical structure, C13H16N4OS, CAS 1043390-97-1
N-(2,5-Dimethyl-phenyl)-2-(5-mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-acetamide
CAS 1043390-97-1C13H16N4OS
2-(5-Mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-N-m-tolyl-acetamide chemical structure, C12H14N4OS, CAS 946758-56-1
2-(5-Mercapto-4-methyl-4H-[1,2,4]triazol-3-yl)-N-m-tolyl-acetamide
CAS 946758-56-1C12H14N4OS