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Murcko scaffold

4-(Pyridin-2-yl)pyrrolidin-2-one scaffold

32 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
32
With full pages
4
Scaffold SMILES

O=C1CC(c2ccccn2)CN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Pyridin-2-yl)pyrrolidin-2-one page
Murcko scaffold O=C1CC(c2ccccn2)CN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

4-(3-Methoxypyridin-2-yl)pyrrolidin-2-one chemical structure, C10H12N2O2, CAS 139746-00-2
4-(3-Methoxypyridin-2-yl)pyrrolidin-2-one
CAS 139746-00-2C10H12N2O2
4-(Pyridin-2-yl)pyrrolidin-2-one chemical structure, C9H10N2O, CAS 28311-29-7
4-(Pyridin-2-yl)pyrrolidin-2-one
CAS 28311-29-7C9H10N2O
Ethyl 2-(5-oxo-3-(pyridin-2-yl)pyrrolidin-3-yl)acetate chemical structure, C13H16N2O3, CAS 178372-18-4
Ethyl 2-(5-oxo-3-(pyridin-2-yl)pyrrolidin-3-yl)acetate
CAS 178372-18-4C13H16N2O3
4-Methyl-4-(pyridin-2-yl)pyrrolidin-2-one chemical structure, C10H12N2O, CAS 1461715-03-6
4-Methyl-4-(pyridin-2-yl)pyrrolidin-2-one
CAS 1461715-03-6C10H12N2O
4-(5-Methylpyridin-2-yl)pyrrolidin-2-one chemical structure, C10H12N2O, CAS 1367023-58-2
4-(5-Methylpyridin-2-yl)pyrrolidin-2-one
CAS 1367023-58-2C10H12N2O
5-Oxo-3-(pyridin-2-yl)pyrrolidine-3-carboxylic acid chemical structure, C10H10N2O3, CAS 1522612-65-2
5-Oxo-3-(pyridin-2-yl)pyrrolidine-3-carboxylic acid
CAS 1522612-65-2C10H10N2O3
4-(6-Methoxypyridin-2-yl)pyrrolidin-2-one chemical structure, C10H12N2O2, CAS 1366981-57-8
4-(6-Methoxypyridin-2-yl)pyrrolidin-2-one
CAS 1366981-57-8C10H12N2O2
4-(5-Bromopyridin-2-yl)pyrrolidin-2-one chemical structure, C9H9BrN2O, CAS 1367106-91-9
4-(5-Bromopyridin-2-yl)pyrrolidin-2-one
CAS 1367106-91-9C9H9BrN2O
Sodium 5-oxo-3-(pyridin-2-yl)pyrrolidine-3-carboxylate chemical structure, C10H9N2NaO3, CAS 1864060-95-6
Sodium 5-oxo-3-(pyridin-2-yl)pyrrolidine-3-carboxylate
CAS 1864060-95-6C10H9N2NaO3
4-(Hydroxymethyl)-4-(pyridin-2-yl)pyrrolidin-2-one chemical structure, C10H12N2O2, CAS 1864051-60-4
4-(Hydroxymethyl)-4-(pyridin-2-yl)pyrrolidin-2-one
CAS 1864051-60-4C10H12N2O2
4-(3-Methylpyridin-2-yl)pyrrolidin-2-one chemical structure, C10H12N2O, CAS 1367167-07-4
4-(3-Methylpyridin-2-yl)pyrrolidin-2-one
CAS 1367167-07-4C10H12N2O
4-(6-Bromopyridin-2-yl)pyrrolidin-2-one chemical structure, C9H9BrN2O, CAS 1367027-60-8
4-(6-Bromopyridin-2-yl)pyrrolidin-2-one
CAS 1367027-60-8C9H9BrN2O
4-(6-Methylpyridin-2-yl)pyrrolidin-2-one chemical structure, C10H12N2O, CAS 1367023-69-5
4-(6-Methylpyridin-2-yl)pyrrolidin-2-one
CAS 1367023-69-5C10H12N2O
4-(4-Methylpyridin-2-yl)pyrrolidin-2-one chemical structure, C10H12N2O, CAS 1366846-19-6
4-(4-Methylpyridin-2-yl)pyrrolidin-2-one
CAS 1366846-19-6C10H12N2O
4-(5-Fluoropyridin-2-yl)pyrrolidin-2-one chemical structure, C9H9FN2O, CAS 1366978-22-4
4-(5-Fluoropyridin-2-yl)pyrrolidin-2-one
CAS 1366978-22-4C9H9FN2O
4-(3-Fluoropyridin-2-yl)pyrrolidin-2-one chemical structure, C9H9FN2O, CAS 1366978-42-8
4-(3-Fluoropyridin-2-yl)pyrrolidin-2-one
CAS 1366978-42-8C9H9FN2O
4-(3,5-Dichloropyridin-2-yl)pyrrolidin-2-one chemical structure, C9H8Cl2N2O, CAS 1366923-46-7
4-(3,5-Dichloropyridin-2-yl)pyrrolidin-2-one
CAS 1366923-46-7C9H8Cl2N2O
4-(6-Chloropyridin-2-yl)pyrrolidin-2-one chemical structure, C9H9ClN2O, CAS 1366830-39-8
4-(6-Chloropyridin-2-yl)pyrrolidin-2-one
CAS 1366830-39-8C9H9ClN2O
4-(4-Chloropyridin-2-yl)pyrrolidin-2-one chemical structure, C9H9ClN2O, CAS 1366765-04-9
4-(4-Chloropyridin-2-yl)pyrrolidin-2-one
CAS 1366765-04-9C9H9ClN2O
4-(3-Bromopyridin-2-yl)pyrrolidin-2-one chemical structure, C9H9BrN2O, CAS 1367022-48-7
4-(3-Bromopyridin-2-yl)pyrrolidin-2-one
CAS 1367022-48-7C9H9BrN2O
4-(4-Methoxypyridin-2-yl)pyrrolidin-2-one chemical structure, C10H12N2O2, CAS 1366826-15-4
4-(4-Methoxypyridin-2-yl)pyrrolidin-2-one
CAS 1366826-15-4C10H12N2O2
4-(5-Methoxypyridin-2-yl)pyrrolidin-2-one chemical structure, C10H12N2O2, CAS 1367203-53-9
4-(5-Methoxypyridin-2-yl)pyrrolidin-2-one
CAS 1367203-53-9C10H12N2O2
Rel-(3R,4S)-3-amino-4-(3-fluoro-5-methoxypyridin-2-yl)pyrrolidin-2-one chemical structure, C10H12FN3O2, CAS 1784748-24-8
Rel-(3R,4S)-3-amino-4-(3-fluoro-5-methoxypyridin-2-yl)pyrrolidin-2-one
CAS 1784748-24-8C10H12FN3O2
Rel-(3R,4R)-4-(3-fluoro-5-methoxypyridin-2-yl)-2-oxopyrrolidine-3-carboxylic acid chemical structure, C11H11FN2O4, CAS 1784747-84-7
Rel-(3R,4R)-4-(3-fluoro-5-methoxypyridin-2-yl)-2-oxopyrrolidine-3-carboxylic acid
CAS 1784747-84-7C11H11FN2O4