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Murcko scaffold

Pyrrolo(1,2-a)pyrazine scaffold

153 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
9
Chemicals
153
With full pages
24
Scaffold SMILES

c1cc2cnccn2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrrolo(1,2-a)pyrazine page
Murcko scaffold c1cc2cnccn2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 153 chemicals

7-Methyl-6,8-bis(methylthio)pyrrolo(1,2-a)pyrazine chemical structure, C10H12N2S2, CAS 84201-40-1
7-Methyl-6,8-bis(methylthio)pyrrolo(1,2-a)pyrazine
CAS 84201-40-1C10H12N2S2
1-Methylpyrrolo(1,2-a)pyrazine chemical structure, C8H8N2, CAS 64608-59-9
1-Methylpyrrolo(1,2-a)pyrazine
CAS 64608-59-9C8H8N2
4-Methylpyrrolo[1,2-a]pyrazine chemical structure, C8H8N2, CAS 64608-60-2
4-Methylpyrrolo[1,2-a]pyrazine
CAS 64608-60-2C8H8N2
2-Aminopyrrolo[1,2-a]pyrazin-2-ium chemical structure, C7H8N3+, CAS 179381-18-1
2-Aminopyrrolo[1,2-a]pyrazin-2-ium
CAS 179381-18-1C7H8N3+
1,6-Dimethylpyrrolo[1,2-a]pyrazine chemical structure, C9H10N2, CAS 138350-47-7
1,6-Dimethylpyrrolo[1,2-a]pyrazine
CAS 138350-47-7C9H10N2
Pyrrolo[1,2-a]pyrazine-8-carbaldehyde chemical structure, C8H6N2O, CAS 179381-15-8
Pyrrolo[1,2-a]pyrazine-8-carbaldehyde
CAS 179381-15-8C8H6N2O
8-Bromopyrrolo[1,2-a]pyrazine chemical structure, C7H5BrN2, CAS 158945-75-6
8-Bromopyrrolo[1,2-a]pyrazine
CAS 158945-75-6C7H5BrN2
Pyrrolo[1,2-a]pyrazine-4-carbaldehyde chemical structure, C8H6N2O, CAS 116758-05-5
Pyrrolo[1,2-a]pyrazine-4-carbaldehyde
CAS 116758-05-5C8H6N2O
Pyrrolo(1,2-a)pyrazine chemical structure, C7H6N2, CAS 274-45-3
Pyrrolo(1,2-a)pyrazine
CAS 274-45-3C7H6N2
Pyrrolo[1,2-a]pyrazinium, 2,6-dimethyl-1-(1-methylethyl)-, iodide chemical structure, C12H17IN2, CAS 148096-98-4
Pyrrolo[1,2-a]pyrazinium, 2,6-dimethyl-1-(1-methylethyl)-, iodide
CAS 148096-98-4C12H17IN2
1,3-Dimethylpyrrolo[1,2-a]pyrazine chemical structure, C9H10N2, CAS 64608-62-4
1,3-Dimethylpyrrolo[1,2-a]pyrazine
CAS 64608-62-4C9H10N2
1,4-Dimethylpyrrolo[1,2-a]pyrazine chemical structure, C9H10N2, CAS 64608-63-5
1,4-Dimethylpyrrolo[1,2-a]pyrazine
CAS 64608-63-5C9H10N2
3-Methylpyrrolo[1,2-a]pyrazine chemical structure, C8H8N2, CAS 64608-61-3
3-Methylpyrrolo[1,2-a]pyrazine
CAS 64608-61-3C8H8N2
3,4-Dimethylpyrrolo[1,2-a]pyrazine chemical structure, C9H10N2, CAS 64608-64-6
3,4-Dimethylpyrrolo[1,2-a]pyrazine
CAS 64608-64-6C9H10N2
1,3,4-Trimethylpyrrolo[1,2-a]pyrazine chemical structure, C10H12N2, CAS 110674-43-6
1,3,4-Trimethylpyrrolo[1,2-a]pyrazine
CAS 110674-43-6C10H12N2
3,6,7-Trimethylpyrrolo[1,2-a]pyrazine chemical structure, C10H12N2, CAS 95407-80-0
3,6,7-Trimethylpyrrolo[1,2-a]pyrazine
CAS 95407-80-0C10H12N2
1,3,7-Trimethylpyrrolo[1,2-a]pyrazine chemical structure, C10H12N2, CAS 95407-83-3
1,3,7-Trimethylpyrrolo[1,2-a]pyrazine
CAS 95407-83-3C10H12N2
1,3,6,7-Tetramethylpyrrolo[1,2-A]pyrazine chemical structure, C11H14N2, CAS 95407-84-4
1,3,6,7-Tetramethylpyrrolo[1,2-A]pyrazine
CAS 95407-84-4C11H14N2
1,3,4,7-Tetramethylpyrrolo[1,2-A]pyrazine chemical structure, C11H14N2, CAS 95407-86-6
1,3,4,7-Tetramethylpyrrolo[1,2-A]pyrazine
CAS 95407-86-6C11H14N2
1-Methoxy-3,7-dimethylpyrrolo[1,2-A]pyrazine chemical structure, C10H12N2O, CAS 95407-89-9
1-Methoxy-3,7-dimethylpyrrolo[1,2-A]pyrazine
CAS 95407-89-9C10H12N2O
1-Chloro-7-methylpyrrolo[1,2-a]pyrazine chemical structure, C8H7ClN2, CAS 118355-96-7
1-Chloro-7-methylpyrrolo[1,2-a]pyrazine
CAS 118355-96-7C8H7ClN2
1-Isopropyl-7-methylpyrrolo[1,2-a]pyrazine chemical structure, C11H14N2, CAS 118356-01-7
1-Isopropyl-7-methylpyrrolo[1,2-a]pyrazine
CAS 118356-01-7C11H14N2
2-(2-Ethoxy-2-oxoethyl)-1-methyl-2H-pyrrolo[1,2-a]pyrazin-5-ium bromide chemical structure, C12H15BrN2O2, CAS 138747-11-2
2-(2-Ethoxy-2-oxoethyl)-1-methyl-2H-pyrrolo[1,2-a]pyrazin-5-ium bromide
CAS 138747-11-2C12H15BrN2O2
1,3,6-Trimethylpyrrolo[1,2-a]pyrazine chemical structure, C10H12N2, CAS 147674-37-1
1,3,6-Trimethylpyrrolo[1,2-a]pyrazine
CAS 147674-37-1C10H12N2