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Murcko scaffold

4,4'-(1H-1,2,4-Triazole-3,5-diyl)bis(pyridine) scaffold

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
12
With full pages
3
Scaffold SMILES

c1cc(-c2n[nH]c(-c3ccncc3)n2)ccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4,4'-(1H-1,2,4-Triazole-3,5-diyl)bis(pyridine) page
Murcko scaffold c1cc(-c2n[nH]c(-c3ccncc3)n2)ccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

1H-1,2,4-Triazole, 1-amino-3,5-bis(4-pyridyl)- chemical structure, C12H10N6, CAS 4923-06-2
1H-1,2,4-Triazole, 1-amino-3,5-bis(4-pyridyl)-
CAS 4923-06-2C12H10N6
3,5-Di(pyridin-4-yl)-4H-1,2,4-triazol-4-amine chemical structure, C12H10N6, CAS 38634-05-8
3,5-Di(pyridin-4-yl)-4H-1,2,4-triazol-4-amine
CAS 38634-05-8C12H10N6
4,4'-(1H-1,2,4-Triazole-3,5-diyl)bis(pyridine) chemical structure, C12H9N5, CAS 4329-78-6
4,4'-(1H-1,2,4-Triazole-3,5-diyl)bis(pyridine)
CAS 4329-78-6C12H9N5
Topiroxostat chemical structure, C13H8N6, CAS 577778-58-6
Topiroxostat
CAS 577778-58-6C13H8N6
Topiroxostat tosylate chemical structure, C20H16N6O3S, CAS 577778-88-2
Topiroxostat tosylate
CAS 577778-88-2C20H16N6O3S
3-(3,5-Di(pyridin-4-yl)-1H-1,2,4-triazol-1-yl)propanoic acid chemical structure, C15H13N5O2, CAS 55785-86-9
3-(3,5-Di(pyridin-4-yl)-1H-1,2,4-triazol-1-yl)propanoic acid
CAS 55785-86-9C15H13N5O2
Methyl 2-(3,5-di(pyridin-4-yl)-1H-1,2,4-triazol-1-yl)acetate chemical structure, C15H13N5O2, CAS 1171933-14-4
Methyl 2-(3,5-di(pyridin-4-yl)-1H-1,2,4-triazol-1-yl)acetate
CAS 1171933-14-4C15H13N5O2
Ethyl 2-(3,5-di(pyridin-4-yl)-1H-1,2,4-triazol-1-yl)acetate chemical structure, C16H15N5O2, CAS 1171933-16-6
Ethyl 2-(3,5-di(pyridin-4-yl)-1H-1,2,4-triazol-1-yl)acetate
CAS 1171933-16-6C16H15N5O2
Topiroxostat impurity 22 chemical structure, C14H7N7, CAS 1199273-82-9
Topiroxostat impurity 22
CAS 1199273-82-9C14H7N7
4-(3-(Pyridin-4-yl)-1H-1,2,4-triazol-5-yl)picolinamide chemical structure, C13H10N6O, CAS 1992028-94-0
4-(3-(Pyridin-4-yl)-1H-1,2,4-triazol-5-yl)picolinamide
CAS 1992028-94-0C13H10N6O
Topiroxostat impurity I chemical structure, C13H9N5O2, CAS 2044702-36-3
Topiroxostat impurity I
CAS 2044702-36-3C13H9N5O2
4-(3-(Pyridin-4-yl)-1H-1,2,4-triazol-5-yl)picolinimidohydrazide chemical structure, C13H12N8, CAS 2044706-50-3
4-(3-(Pyridin-4-yl)-1H-1,2,4-triazol-5-yl)picolinimidohydrazide
CAS 2044706-50-3C13H12N8