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Murcko scaffold

3-Phenylpyrimidine-2,4(1H,3H)-dione scaffold

128 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
128
With full pages
6
Scaffold SMILES

O=c1cc[nH]c(=O)n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylpyrimidine-2,4(1H,3H)-dione page
Murcko scaffold O=c1cc[nH]c(=O)n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 128 chemicals

5-(Diethylamino)-1-ethyl-6-methyl-3-phenyl-2,4(1H,3H)-pyrimidinedione chemical structure, C17H23N3O2, CAS 33872-85-4
5-(Diethylamino)-1-ethyl-6-methyl-3-phenyl-2,4(1H,3H)-pyrimidinedione
CAS 33872-85-4C17H23N3O2
Uracil, 5-(dimethylamino)-1-ethyl-6-methyl-3-phenyl- chemical structure, C15H19N3O2, CAS 32150-75-7
Uracil, 5-(dimethylamino)-1-ethyl-6-methyl-3-phenyl-
CAS 32150-75-7C15H19N3O2
Uracil, 1-allyl-5-(dimethylamino)-6-methyl-3-phenyl- chemical structure, C16H19N3O2, CAS 32150-76-8
Uracil, 1-allyl-5-(dimethylamino)-6-methyl-3-phenyl-
CAS 32150-76-8C16H19N3O2
2,4(1H,3H)-Pyrimidinedione, 1,6-dimethyl-3-phenyl- chemical structure, C12H12N2O2, CAS 38507-46-9
2,4(1H,3H)-Pyrimidinedione, 1,6-dimethyl-3-phenyl-
CAS 38507-46-9C12H12N2O2
2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-5-ethoxy-2-fluorophenyl)-1-methyl-6-(trifluoromethyl)- chemical structure, C14H11ClF4N2O3, CAS 114168-56-8
2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-5-ethoxy-2-fluorophenyl)-1-methyl-6-(trifluoromethyl)-
CAS 114168-56-8C14H11ClF4N2O3
2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-2-fluoro-5-((methylthio)methoxy)phenyl)-1-methyl-6-(trifluoromethyl)- chemical structure, C14H11ClF4N2O3S, CAS 114168-72-8
2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-2-fluoro-5-((methylthio)methoxy)phenyl)-1-methyl-6-(trifluoromethyl)-
CAS 114168-72-8C14H11ClF4N2O3S
2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-2-fluoro-5-(1-methylethoxy)phenyl)-1,6-dimethyl- chemical structure, C15H16ClFN2O3, CAS 114169-03-8
2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-2-fluoro-5-(1-methylethoxy)phenyl)-1,6-dimethyl-
CAS 114169-03-8C15H16ClFN2O3
Benzoic acid, 2-chloro-5-(3-(difluoromethyl)-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl)-4-fluoro-, 1-methylethyl ester chemical structure, C16H14ClF3N2O4, CAS 120890-05-3
Benzoic acid, 2-chloro-5-(3-(difluoromethyl)-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl)-4-fluoro-, 1-methylethyl ester
CAS 120890-05-3C16H14ClF3N2O4
Methanesulfonamide, N-(2-chloro-5-(3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)-pyrimidinyl)-4-fluorophenyl)-N-methyl- chemical structure, C14H12ClF4N3O4S, CAS 133762-95-5
Methanesulfonamide, N-(2-chloro-5-(3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)-pyrimidinyl)-4-fluorophenyl)-N-methyl-
CAS 133762-95-5C14H12ClF4N3O4S
2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-3-(1-methylethoxy)phenyl)-1-methyl-6-(trifluoromethyl)- chemical structure, C15H14ClF3N2O3, CAS 133762-96-6
2,4(1H,3H)-Pyrimidinedione, 3-(4-chloro-3-(1-methylethoxy)phenyl)-1-methyl-6-(trifluoromethyl)-
CAS 133762-96-6C15H14ClF3N2O3
1,3-Difluoropropan-2-yl 2-chloro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-3,6-dihydropyrimidin-1(2H)-yl]benzoate chemical structure, C16H12ClF5N2O4, CAS 133762-98-8
1,3-Difluoropropan-2-yl 2-chloro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-3,6-dihydropyrimidin-1(2H)-yl]benzoate
CAS 133762-98-8C16H12ClF5N2O4
Methanesulfonamide, N-(2-chloro-5-(3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)-pyrimidinyl)phenyl)- chemical structure, C13H11ClF3N3O4S, CAS 133762-99-9
Methanesulfonamide, N-(2-chloro-5-(3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1(2H)-pyrimidinyl)phenyl)-
CAS 133762-99-9C13H11ClF3N3O4S
Flupropacil chemical structure, C16H14ClF3N2O4, CAS 120890-70-2
Flupropacil
CAS 120890-70-2C16H14ClF3N2O4
Uracil, 1,6-dimethyl-5-(dimethylamino)-3-phenyl- chemical structure, C14H17N3O2, CAS 31991-96-5
Uracil, 1,6-dimethyl-5-(dimethylamino)-3-phenyl-
CAS 31991-96-5C14H17N3O2
Uracil, 5-(butylamino)-1,6-dimethyl-3-phenyl- chemical structure, C16H21N3O2, CAS 31991-98-7
Uracil, 5-(butylamino)-1,6-dimethyl-3-phenyl-
CAS 31991-98-7C16H21N3O2
Uracil, 5-(diethylamino)-1,6-dimethyl-3-phenyl- chemical structure, C16H21N3O2, CAS 31991-99-8
Uracil, 5-(diethylamino)-1,6-dimethyl-3-phenyl-
CAS 31991-99-8C16H21N3O2
Uracil, 1,6-dimethyl-5-(isopropylamino)-3-phenyl- chemical structure, C15H19N3O2, CAS 31992-00-4
Uracil, 1,6-dimethyl-5-(isopropylamino)-3-phenyl-
CAS 31992-00-4C15H19N3O2
Uracil, 5-bromo-1,6-dimethyl-3-phenyl- chemical structure, C12H11BrN2O2, CAS 32000-65-0
Uracil, 5-bromo-1,6-dimethyl-3-phenyl-
CAS 32000-65-0C12H11BrN2O2
Uracil, 1,6-dimethyl-5-iodo-3-phenyl- chemical structure, C12H11IN2O2, CAS 32000-67-2
Uracil, 1,6-dimethyl-5-iodo-3-phenyl-
CAS 32000-67-2C12H11IN2O2
Uracil, 1-allyl-5-bromo-6-methyl-3-phenyl- chemical structure, C14H13BrN2O2, CAS 32000-72-9
Uracil, 1-allyl-5-bromo-6-methyl-3-phenyl-
CAS 32000-72-9C14H13BrN2O2
5-sec-Butylamino-1,6-dimethyl-3-phenyluracil chemical structure, C16H21N3O2, CAS 32150-70-2
5-sec-Butylamino-1,6-dimethyl-3-phenyluracil
CAS 32150-70-2C16H21N3O2
2,4(1H,3H)-Pyrimidinedione, 5-(dimethylamino)-1-(2-hydroxyethyl)-6-methyl-3-phenyl- chemical structure, C15H19N3O3, CAS 38507-22-1
2,4(1H,3H)-Pyrimidinedione, 5-(dimethylamino)-1-(2-hydroxyethyl)-6-methyl-3-phenyl-
CAS 38507-22-1C15H19N3O3
Ethyl 2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate chemical structure, C13H12N2O4, CAS 302967-61-9
Ethyl 2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
CAS 302967-61-9C13H12N2O4
6-Methyl-3-phenyluracil chemical structure, C11H10N2O2, CAS 1804-04-2
6-Methyl-3-phenyluracil
CAS 1804-04-2C11H10N2O2