CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 17 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
15
With full pages
3
Scaffold SMILES

O=C1C(=C2C=CNC=C2)C(=O)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C(=C2C=CNC=C2)C(=O)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

1,3-Indandione, 2-(1-ethyl-4(1H)-pyridinylidene)- chemical structure, C16H13NO2, CAS 49803-30-7
1,3-Indandione, 2-(1-ethyl-4(1H)-pyridinylidene)-
CAS 49803-30-7C16H13NO2
1,3-Indandione, 2-(1-(1-methylethyl)-4(1H)-pyridinylidene)- chemical structure, C17H15NO2, CAS 49803-32-9
1,3-Indandione, 2-(1-(1-methylethyl)-4(1H)-pyridinylidene)-
CAS 49803-32-9C17H15NO2
2-[1-[3-(Dimethylamino)propyl]pyridin-4-ylidene]indene-1,3-dione chemical structure, C19H20N2O2, CAS 62295-47-0
2-[1-[3-(Dimethylamino)propyl]pyridin-4-ylidene]indene-1,3-dione
CAS 62295-47-0C19H20N2O2
2-[1-(2-Diethylaminoethyl)pyridin-4-ylidene]indene-1,3-dione chemical structure, C20H22N2O2, CAS 62295-40-3
2-[1-(2-Diethylaminoethyl)pyridin-4-ylidene]indene-1,3-dione
CAS 62295-40-3C20H22N2O2
2-[1-[2-(2-Hydroxyethylamino)ethyl]-2,6-dimethylpyridin-4-ylidene]indene-1,3-dione chemical structure, C20H22N2O3, CAS 81959-89-9
2-[1-[2-(2-Hydroxyethylamino)ethyl]-2,6-dimethylpyridin-4-ylidene]indene-1,3-dione
CAS 81959-89-9C20H22N2O3
2-(2,6-Dimethyl-1-propa-1,2-dienylpyridin-4-ylidene)indene-1,3-dione chemical structure, C19H15NO2, CAS 80672-64-6
2-(2,6-Dimethyl-1-propa-1,2-dienylpyridin-4-ylidene)indene-1,3-dione
CAS 80672-64-6C19H15NO2
2-(1-Methylpyridin-4-ylidene)indene-1,3-dione chemical structure, C15H11NO2, CAS 49803-29-4
2-(1-Methylpyridin-4-ylidene)indene-1,3-dione
CAS 49803-29-4C15H11NO2
2-(2,6-Dimethyl-1-propan-2-ylpyridin-4-ylidene)indene-1,3-dione chemical structure, C19H19NO2, CAS 71107-33-0
2-(2,6-Dimethyl-1-propan-2-ylpyridin-4-ylidene)indene-1,3-dione
CAS 71107-33-0C19H19NO2
1,3-Indandione, 2-(1-(2-methoxyethyl)-4(1H)-pyridinylidene)- chemical structure, C17H15NO3, CAS 54778-70-0
1,3-Indandione, 2-(1-(2-methoxyethyl)-4(1H)-pyridinylidene)-
CAS 54778-70-0C17H15NO3
2-[1-(2-Oxopropyl)pyridin-4(1H)-ylidene]-1H-indene-1,3(2H)-dione chemical structure, C17H13NO3, CAS 55022-39-4
2-[1-(2-Oxopropyl)pyridin-4(1H)-ylidene]-1H-indene-1,3(2H)-dione
CAS 55022-39-4C17H13NO3
2-[1-(3-Aminopropyl)pyridin-4(1H)-ylidene]-1H-indene-1,3(2H)-dione chemical structure, C17H16N2O2, CAS 62295-45-8
2-[1-(3-Aminopropyl)pyridin-4(1H)-ylidene]-1H-indene-1,3(2H)-dione
CAS 62295-45-8C17H16N2O2
N-(2-Chloroethyl)-N'-{3-[4-(1,3-dioxo-1,3-dihydro-2H-inden-2-ylidene)-2,6-dimethylpyridin-1(4H)-yl]propyl}-N-nitrosourea chemical structure, C22H23ClN4O4, CAS 95835-46-4
N-(2-Chloroethyl)-N'-{3-[4-(1,3-dioxo-1,3-dihydro-2H-inden-2-ylidene)-2,6-dimethylpyridin-1(4H)-yl]propyl}-N-nitrosourea
CAS 95835-46-4C22H23ClN4O4
2-[1-(3-Chloropropyl)pyridin-4(1H)-ylidene]-1H-indene-1,3(2H)-dione chemical structure, C17H14ClNO2, CAS 62295-67-4
2-[1-(3-Chloropropyl)pyridin-4(1H)-ylidene]-1H-indene-1,3(2H)-dione
CAS 62295-67-4C17H14ClNO2
2-[1-(2-Bromoethyl)pyridin-4(1H)-ylidene]-1H-indene-1,3(2H)-dione chemical structure, C16H12BrNO2, CAS 62294-69-3
2-[1-(2-Bromoethyl)pyridin-4(1H)-ylidene]-1H-indene-1,3(2H)-dione
CAS 62294-69-3C16H12BrNO2
2-[1-(2-Chloroethyl)pyridin-4(1H)-ylidene]-1H-indene-1,3(2H)-dione chemical structure, C16H12ClNO2, CAS 62294-68-2
2-[1-(2-Chloroethyl)pyridin-4(1H)-ylidene]-1H-indene-1,3(2H)-dione
CAS 62294-68-2C16H12ClNO2