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Murcko scaffold

Ring system with 2 rings and 14 atoms

17 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
17
With full pages
4
Scaffold SMILES

O=c1occcc1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1occcc1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

3-Benzyl-6-chloro-2-pyrone chemical structure, C12H9ClO2, CAS 85533-80-8
3-Benzyl-6-chloro-2-pyrone
CAS 85533-80-8C12H9ClO2
3-[1-(4-Chlorophenyl)-2-nitroethyl]-4-hydroxy-6-methylpyran-2-one chemical structure, C14H12ClNO5, CAS 325474-40-6
3-[1-(4-Chlorophenyl)-2-nitroethyl]-4-hydroxy-6-methylpyran-2-one
CAS 325474-40-6C14H12ClNO5
Arzanol chemical structure, C22H26O7, CAS 32274-52-5
Arzanol
CAS 32274-52-5C22H26O7
4-Hydroxy-3-[1-(4-methoxyphenyl)-2-nitroethyl]-6-methyl-2H-pyran-2-one chemical structure, C15H15NO6, CAS 315697-50-8
4-Hydroxy-3-[1-(4-methoxyphenyl)-2-nitroethyl]-6-methyl-2H-pyran-2-one
CAS 315697-50-8C15H15NO6
3-[1-(2,4-Dichlorophenyl)-2-nitroethyl]-4-hydroxy-6-methyl-2H-pyran-2-one chemical structure, C14H11Cl2NO5, CAS 315234-76-5
3-[1-(2,4-Dichlorophenyl)-2-nitroethyl]-4-hydroxy-6-methyl-2H-pyran-2-one
CAS 315234-76-5C14H11Cl2NO5
3-[1-(4-Chlorophenyl)-3-oxobutyl]-4-hydroxy-6-methyl-2H-pyran-2-one chemical structure, C16H15ClO4, CAS 88639-77-4
3-[1-(4-Chlorophenyl)-3-oxobutyl]-4-hydroxy-6-methyl-2H-pyran-2-one
CAS 88639-77-4C16H15ClO4
3-[1-(4-Chlorophenyl)propyl]-4-hydroxy-6-methyl-2H-pyran-2-one chemical structure, C15H15ClO3, CAS 88639-75-2
3-[1-(4-Chlorophenyl)propyl]-4-hydroxy-6-methyl-2H-pyran-2-one
CAS 88639-75-2C15H15ClO3
Communol A chemical structure, C16H16O6, CAS 1421931-60-3
Communol A
CAS 1421931-60-3C16H16O6
Arenol chemical structure, C21H24O7, CAS 32274-51-4
Arenol
CAS 32274-51-4C21H24O7
Methyl 3-((4-fluorophenyl)(hydroxy)methyl)-2-oxo-2H-pyran-5-carboxylate chemical structure, C14H11FO5, CAS 2291198-94-0
Methyl 3-((4-fluorophenyl)(hydroxy)methyl)-2-oxo-2H-pyran-5-carboxylate
CAS 2291198-94-0C14H11FO5
Methyl 3-(hydroxy(2-nitrophenyl)methyl)-2-oxo-2H-pyran-5-carboxylate chemical structure, C14H11NO7, CAS 2291199-00-1
Methyl 3-(hydroxy(2-nitrophenyl)methyl)-2-oxo-2H-pyran-5-carboxylate
CAS 2291199-00-1C14H11NO7
Methyl 3-((2-bromophenyl)(hydroxy)methyl)-2-oxo-2H-pyran-5-carboxylate chemical structure, C14H11BrO5, CAS 2291198-96-2
Methyl 3-((2-bromophenyl)(hydroxy)methyl)-2-oxo-2H-pyran-5-carboxylate
CAS 2291198-96-2C14H11BrO5
Methyl 3-(hydroxy(4-(trifluoromethyl)phenyl)methyl)-2-oxo-2H-pyran-5-carboxylate chemical structure, C15H11F3O5, CAS 2291199-01-2
Methyl 3-(hydroxy(4-(trifluoromethyl)phenyl)methyl)-2-oxo-2H-pyran-5-carboxylate
CAS 2291199-01-2C15H11F3O5
Methyl 3-(hydroxy(4-nitrophenyl)methyl)-2-oxo-2H-pyran-5-carboxylate chemical structure, C14H11NO7, CAS 2291198-91-7
Methyl 3-(hydroxy(4-nitrophenyl)methyl)-2-oxo-2H-pyran-5-carboxylate
CAS 2291198-91-7C14H11NO7
Methyl 3-((4-cyanophenyl)(hydroxy)methyl)-2-oxo-2H-pyran-5-carboxylate chemical structure, C15H11NO5, CAS 2291198-98-4
Methyl 3-((4-cyanophenyl)(hydroxy)methyl)-2-oxo-2H-pyran-5-carboxylate
CAS 2291198-98-4C15H11NO5
Methyl 3-((4-bromophenyl)(hydroxy)methyl)-2-oxo-2H-pyran-5-carboxylate chemical structure, C14H11BrO5, CAS 2291198-95-1
Methyl 3-((4-bromophenyl)(hydroxy)methyl)-2-oxo-2H-pyran-5-carboxylate
CAS 2291198-95-1C14H11BrO5
Methyl 3-(hydroxy(4-methoxyphenyl)methyl)-2-oxo-2H-pyran-5-carboxylate chemical structure, C15H14O6, CAS 2291199-02-3
Methyl 3-(hydroxy(4-methoxyphenyl)methyl)-2-oxo-2H-pyran-5-carboxylate
CAS 2291199-02-3C15H14O6