Murcko scaffold
6,7-Dihydro-5H-2-pyrindine scaffold
255 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 255
- With full pages
- 26
Scaffold SMILES
c1cc2c(cn1)CCC2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 255 chemicals
(7S)-6,7-Dihydro-4,7-dimethyl-5H-cyclopenta(c)pyridine
CAS 524-03-8C10H13N
6,7-Dihydro-5H-2-pyrindine
CAS 533-35-7C8H9N
Isocantleyine
CAS 143564-04-9C11H13NO3
Rhexifoline
CAS 93915-32-3C11H13NO3
(7R)-6,7-Dihydro-7-methyl-5H-cyclopenta(c)pyridine-4-carboxaldehyde
CAS 18070-40-1C10H11NO
Methyl (6S,7R)-6,7-dihydro-6-hydroxy-7-methyl-5H-cyclopenta(c)pyridine-4-carboxylate
CAS 30333-81-4C11H13NO3
Valerianine
CAS 30634-66-3C11H15NO
5H-2-Pyrindine-4-carboxamide, 6,7-dihydro-3-amino-
CAS 130688-30-1C9H11N3O
![1,3-Dichloro-5H,6H,7H-cyclopenta[c]pyridine-4-carbonitrile chemical structure, C9H6Cl2N2, CAS 15524-46-6](/s/ZCRYHTATGWYSMB-UHFFFAOYSA-N.svg)
1,3-Dichloro-5H,6H,7H-cyclopenta[c]pyridine-4-carbonitrile
CAS 15524-46-6C9H6Cl2N2
![3-Chloro-1-(2-methylpropyl)-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile chemical structure, C13H15ClN2, CAS 799826-04-3](/s/ZSCOCKMKGVEXPM-UHFFFAOYSA-N.svg)
3-Chloro-1-(2-methylpropyl)-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile
CAS 799826-04-3C13H15ClN2
![3-Chloro-1-propan-2-yl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile chemical structure, C12H13ClN2, CAS 836632-47-4](/s/JIWAAPORCIUBBF-UHFFFAOYSA-N.svg)
3-Chloro-1-propan-2-yl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile
CAS 836632-47-4C12H13ClN2
![1-Butyl-3-chloro-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile chemical structure, C13H15ClN2, CAS 488099-91-8](/s/RFHRNSWLUPHUJD-UHFFFAOYSA-N.svg)
1-Butyl-3-chloro-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile
CAS 488099-91-8C13H15ClN2
![3-Methyl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile chemical structure, C10H10N2, CAS 63820-79-1](/s/PRORLERWCVDWTI-UHFFFAOYSA-N.svg)
3-Methyl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile
CAS 63820-79-1C10H10N2
![(7R)-7-Methyl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carboxamide chemical structure, C10H12N2O, CAS 14478-19-4](/s/CPWSAKUPXWXJPQ-ZCFIWIBFSA-N.svg)
(7R)-7-Methyl-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carboxamide
CAS 14478-19-4C10H12N2O
![1,3-Dichloro-6,7-dihydro-5H-cyclopenta[c]pyridine chemical structure, C8H7Cl2N, CAS 72605-56-2](/s/NVSSGOHGTZCSHP-UHFFFAOYSA-N.svg)
1,3-Dichloro-6,7-dihydro-5H-cyclopenta[c]pyridine
CAS 72605-56-2C8H7Cl2N
![5H-Cyclopenta[c]pyridin-5-ol, 6,7-dihydro-4-(2-propenyl)- chemical structure, C11H13NO, CAS 189065-85-8](/s/HQSHSQJTVRLCIK-UHFFFAOYSA-N.svg)
5H-Cyclopenta[c]pyridin-5-ol, 6,7-dihydro-4-(2-propenyl)-
CAS 189065-85-8C11H13NO
![1-(1-(Methylthio)-6,7-dihydro-5H-cyclopenta[c]pyridin-3-yl)ethanone chemical structure, C11H13NOS, CAS 499766-65-3](/s/UTQNIQUAOAXMSS-UHFFFAOYSA-N.svg)
1-(1-(Methylthio)-6,7-dihydro-5H-cyclopenta[c]pyridin-3-yl)ethanone
CAS 499766-65-3C11H13NOS
![Ethyl 3,4-dimethyl-6,7-dihydro-5H-cyclopenta[C]pyridine-1-carboxylate chemical structure, C13H17NO2, CAS 668276-37-7](/s/VXZQRMCEAGIRFD-UHFFFAOYSA-N.svg)
Ethyl 3,4-dimethyl-6,7-dihydro-5H-cyclopenta[C]pyridine-1-carboxylate
CAS 668276-37-7C13H17NO2
![5H-Cyclopenta[C]pyridin-5-ol, 6,7-dihydro- chemical structure, C8H9NO, CAS 937641-51-5](/s/OLQNADLOODXWQI-UHFFFAOYSA-N.svg)
5H-Cyclopenta[C]pyridin-5-ol, 6,7-dihydro-
CAS 937641-51-5C8H9NO
![6,7-Dihydro-5H-cyclopenta[c]pyridin-5-amine chemical structure, C8H10N2, CAS 1260762-34-2](/s/YNLBESQCEDPLSW-UHFFFAOYSA-N.svg)
6,7-Dihydro-5H-cyclopenta[c]pyridin-5-amine
CAS 1260762-34-2C8H10N2
![(7S)-7-Methyl-5H,6H,7H-cyclopenta[C]pyridine-4-carbaldehyde chemical structure, C10H11NO, CAS 21857-96-5](/s/OPRAONAUWNNOOV-ZETCQYMHSA-N.svg)
(7S)-7-Methyl-5H,6H,7H-cyclopenta[C]pyridine-4-carbaldehyde
CAS 21857-96-5C10H11NO
![(7R)-6,7-Dihydro-7-methyl-5H-cyclopenta[c]pyridine-4-carboxylic acid chemical structure, C10H11NO2, CAS 21857-97-6](/s/RLNQBGQGMYNOCX-ZCFIWIBFSA-N.svg)
(7R)-6,7-Dihydro-7-methyl-5H-cyclopenta[c]pyridine-4-carboxylic acid
CAS 21857-97-6C10H11NO2
Plantagonine
CAS 21913-34-8C10H11NO2
![6,7-Dihydro-3,4-dimethyl-5H-cyclopenta[c]pyridine chemical structure, C10H13N, CAS 83458-55-3](/s/UVOACZBCXYHCJI-UHFFFAOYSA-N.svg)
6,7-Dihydro-3,4-dimethyl-5H-cyclopenta[c]pyridine
CAS 83458-55-3C10H13N
- 3-Bromo-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile65996-04-5C9H7BrN2
- 5H-2-Pyrindine-4-carbonitrile, 6,7-dihydro-3-amino-88745-30-6C9H9N3
- 5H,6H,7H-Cyclopenta(c)pyridin-3-amine93587-43-0C8H10N2
- 5H-2-Pyrindine-4-carboxylic acid, 6,7-dihydro-3-amino-93587-44-1C9H10N2O2
- 3-Chloro-5H,6H,7H-cyclopenta[c]pyridine-4-carbonitrile103589-67-9C9H7ClN2
- (5S,7R)-7-Methyl-6,7-dihydro-5H-cyclopenta[c]pyridine-5-ol185067-06-5C9H11NO
- (5R,7R)-7-Methyl-6,7-dihydro-5H-cyclopenta[c]pyridin-5-ol185067-10-1C9H11NO
- 1-Methyl-6,7-dihydro-5H-cyclopenta[c]pyridine121259-09-4C9H11N
- 5H,6H,7H-Cyclopenta[c]pyridine-4-carbonitrile15524-47-7C9H8N2
- Ethyl 3-amino-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carboxylate137676-51-8C11H14N2O2
- Ethyl 6,7-dihydro-5H-cyclopenta[c]pyridine-3-carboxylate74502-48-0C11H13NO2
- Ethyl 6,7-dihydro-5H-cyclopenta[c]pyridine-6-carboxylate607345-41-5C11H13NO2
- 6,7-Dihydro-5H-cyclopenta[c]pyridin-6-amine1314975-12-6C8H10N2
- 1-(5H,6H,7H-Cyclopenta(c)pyridin-6-yl)methanamine1314932-02-9C9H12N2
- 6,7-Dihydro-5H-cyclopenta[c]pyridin-6-ylmethanol607345-42-6C9H11NO
- Ethyl 5H,6H,7H-cyclopenta[c]pyridine-1-carboxylate692729-88-7C11H13NO2
- 5-Ethyl-1-fluoro-6,7-dihydro-5H-cyclopenta[c]pyridine-5,7-diol609771-42-8C10H12FNO2
- (5S)-5-Ethyl-1-fluoro-6,7-dihydro-5H-cyclopenta[c]pyridine-5,6-diol340268-59-9C10H12FNO2
- (S)-6,7-Dihydro-5H-cyclopenta[c]pyridin-7-amine1270182-78-9C8H10N2
- (5s)-5H,6H,7H-Cyclopenta[c]pyridin-5-amine1270027-96-7C8H10N2
- 3-(Chloromethyl)-6,7-dihydro-5H-cyclopenta[c]pyridine910323-86-3C9H10ClN
- 5H-2-Pyrindin-6-ol, 6,7-dihydro-7-methyl-, (6R-cis)-17948-42-4C9H11NO
- 5-Methyl-6,7-dihydro-5H-cyclopenta[c]pyridine83504-33-0C9H11N
- 4-Methyl-6,7-dihydro-5H-cyclopenta[c]pyridine83504-32-9C9H11N
Related scaffolds
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