Murcko scaffold
N-(1H-Benzimidazol-2-ylmethyl)-N-phenylamine scaffold
44 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 17
- Chemicals
- 44
- With full pages
- 13
Scaffold SMILES
c1ccc(NCc2nc3ccccc3[nH]2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold c1ccc(NCc2nc3ccccc3[nH]2)cc1](/scaffold/RICPDSJTBAXDLV-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 44 of 44 chemicals
Anthranilic acid, N-(2-benzimidazolylmethyl)-
CAS 52434-48-7C15H13N3O2
Midamaline
CAS 496-38-8C18H21ClN4
Benzoic acid, p-(N-(benzimidazol-2-ylmethyl)formamido)-
CAS 7399-94-2C16H13N3O3
4-(1H-Benzimidazol-2-ylmethylamino)phenol
CAS 6630-28-0C14H13N3O
N-(1H-Benzimidazol-2-ylmethyl)-2-methoxyaniline
CAS 73259-43-5C15H15N3O
N-(1H-Benzoimidazol-2-ylmethyl)-4-methoxy-aniline
CAS 73259-41-3C15H15N3O
N-(1H-Benzimidazol-2-ylmethyl)-4-chloroaniline
CAS 73259-32-2C14H12ClN3
N-(1H-Benzimidazol-2-ylmethyl)-N-phenylamine
CAS 5805-59-4C14H13N3
4-((1H-Benzimidazol-2-ylmethyl)amino)benzenesulfonamide
CAS 6939-46-4C14H14N4O2S
![2,5-Dichloro-N-[(1-methylbenzimidazol-2-yl)methyl]aniline chemical structure, C15H13Cl2N3, CAS 381201-95-2](/s/ZQMZRHDICAIAPU-UHFFFAOYSA-N.svg)
2,5-Dichloro-N-[(1-methylbenzimidazol-2-yl)methyl]aniline
CAS 381201-95-2C15H13Cl2N3
![4-Chloro-N-[(1-methylbenzimidazol-2-yl)methyl]aniline chemical structure, C15H14ClN3, CAS 309938-33-8](/s/AITINQVEJBXDAD-UHFFFAOYSA-N.svg)
4-Chloro-N-[(1-methylbenzimidazol-2-yl)methyl]aniline
CAS 309938-33-8C15H14ClN3
![4-Ethoxy-N-[(1-methylbenzimidazol-2-yl)methyl]aniline chemical structure, C17H19N3O, CAS 404359-79-1](/s/KVHGQGXLKHHWEP-UHFFFAOYSA-N.svg)
4-Ethoxy-N-[(1-methylbenzimidazol-2-yl)methyl]aniline
CAS 404359-79-1C17H19N3O
![4-[(1-Methylbenzimidazol-2-yl)methylamino]benzenesulfonamide chemical structure, C15H16N4O2S, CAS 309938-32-7](/s/RLWMRQJPJJWGMK-UHFFFAOYSA-N.svg)
4-[(1-Methylbenzimidazol-2-yl)methylamino]benzenesulfonamide
CAS 309938-32-7C15H16N4O2S
![4-Bromo-N-[(1-methylbenzimidazol-2-yl)methyl]aniline chemical structure, C15H14BrN3, CAS 331851-46-8](/s/DAMPPXDFGMIGTC-UHFFFAOYSA-N.svg)
4-Bromo-N-[(1-methylbenzimidazol-2-yl)methyl]aniline
CAS 331851-46-8C15H14BrN3
![2-{[(1-Propyl-1H-benzimidazol-2-yl)methyl]amino}phenol chemical structure, C17H19N3O, CAS 331851-39-9](/s/ORCLWERNIDQHJQ-UHFFFAOYSA-N.svg)
2-{[(1-Propyl-1H-benzimidazol-2-yl)methyl]amino}phenol
CAS 331851-39-9C17H19N3O
(4-Methoxy-phenyl)-(1-methyl-1H-benzoimidazol-2-ylmethyl)-amine
CAS 331851-41-3C16H17N3O
![4-Methyl-N-[(1-methylbenzimidazol-2-yl)methyl]aniline chemical structure, C16H17N3, CAS 331851-42-4](/s/UIDZOGWOSWZXKD-UHFFFAOYSA-N.svg)
4-Methyl-N-[(1-methylbenzimidazol-2-yl)methyl]aniline
CAS 331851-42-4C16H17N3
![3,4-Dimethyl-N-[(1-methylbenzimidazol-2-yl)methyl]aniline chemical structure, C17H19N3, CAS 342384-59-2](/s/QBCJVIIPDOTWHF-UHFFFAOYSA-N.svg)
3,4-Dimethyl-N-[(1-methylbenzimidazol-2-yl)methyl]aniline
CAS 342384-59-2C17H19N3
![4-Fluoro-N-[(1-methylbenzimidazol-2-yl)methyl]aniline chemical structure, C15H14FN3, CAS 342387-27-3](/s/MWMHJOBJEKQQIB-UHFFFAOYSA-N.svg)
4-Fluoro-N-[(1-methylbenzimidazol-2-yl)methyl]aniline
CAS 342387-27-3C15H14FN3
![4-{[(1-Methyl-1H-benzimidazol-2-yl)methyl]amino}benzoic acid chemical structure, C16H15N3O2, CAS 328559-27-9](/s/ZGCFJSLTGOSGBB-UHFFFAOYSA-N.svg)
4-{[(1-Methyl-1H-benzimidazol-2-yl)methyl]amino}benzoic acid
CAS 328559-27-9C16H15N3O2
![4-[(1-Methyl-1H-benzoimidazol-2-ylmethyl)-amino]-benzoic acid ethyl ester chemical structure, C18H19N3O2, CAS 331851-38-8](/s/NOSGJRCODXUOAO-UHFFFAOYSA-N.svg)
4-[(1-Methyl-1H-benzoimidazol-2-ylmethyl)-amino]-benzoic acid ethyl ester
CAS 331851-38-8C18H19N3O2
![2-Methyl-N-[(1-methylbenzimidazol-2-yl)methyl]aniline chemical structure, C16H17N3, CAS 667431-55-2](/s/RDYNZGXJQGAHHV-UHFFFAOYSA-N.svg)
2-Methyl-N-[(1-methylbenzimidazol-2-yl)methyl]aniline
CAS 667431-55-2C16H17N3
![N-Ethyl-N-[(1-methylbenzimidazol-2-yl)methyl]aniline chemical structure, C17H19N3, CAS 876889-51-9](/s/IOBCYLYDLSHIOH-UHFFFAOYSA-N.svg)
N-Ethyl-N-[(1-methylbenzimidazol-2-yl)methyl]aniline
CAS 876889-51-9C17H19N3
![N-Methyl-N-{[1-(propan-2-yl)-1H-1,3-benzodiazol-2-yl]methyl}aniline hydrochloride chemical structure, C18H22ClN3, CAS 1135301-68-6](/s/SWFJCLYIQRQMHV-UHFFFAOYSA-N.svg)
N-Methyl-N-{[1-(propan-2-yl)-1H-1,3-benzodiazol-2-yl]methyl}aniline hydrochloride
CAS 1135301-68-6C18H22ClN3
- 4-{[(5,6-Dichloro-1H-benzimidazol-2-yl)methyl]amino}benzoic acid--hydrogen chloride (1/1)17033-59-9C15H12Cl3N3O2
- 4-{[(1H-1,3-Benzimidazol-2-yl)methyl]amino}benzonitrile--hydrogen chloride (1/1)7144-51-6C15H13ClN4
- Midamaline hydrochloride24360-03-0C18H22Cl2N4
- N-[(5-Methoxy-1H-1,3-benzodiazol-2-yl)methyl]aniline1493279-30-3C15H15N3O
- Dabigatran metabolite M3241015167-27-7C17H17N5O2
- Dabigatran impurity 711422435-40-2C19H20N4O3
- Dabigatran impurity 451117893-66-9C19H18N4O2
- 2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazole-5-carboxylic-d3 Acid Ethyl Ester1346601-47-5C19H18N4O2
- N-(2-Acetamidophenyl)-N-[(1H-benzimidazol-2-yl)methyl]acetamide91362-52-6C18H18N4O2
- 2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazole-5-carboxylic Acid Ethyl Ester Hydrochloride1422435-39-9C19H22ClN5O2
- Dabigatran impurity 91408238-41-4C19H21N5O2
- Des-(3-(Pyridin-2-ylamino)propanoate) Dabigatran Diethyl Ester1422435-37-7C21H24N4O3
- Dabigatran impurity 621807758-61-7C26H32N4O5
- 2-(((4-(((Hexyloxy)carbonyl)carbamoyl)phenyl)amino)methyl)-1-methyl-1H-benzo[d]imidazole-5-carboxylic acid2096992-09-3C24H28N4O5
- 1 suppliersEthyl 2-(((4-(N-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-1H-benzo[d]imidazole-5-carboxylate1408238-36-7C26H33N5O4
- 2-(((4-(N-((Hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-1H-benzo[d]imidazole-5-carboxylic acid (Dabigatran Impurity)1912458-32-2C24H29N5O4
- Methyl 2-(((4-cyanophenyl)amino)methyl)-1-methyl-1H-benzo[d]imidazole-5-carboxylate1970195-83-5C18H16N4O2
- N1,N1-Dimethyl-N2-[(1-methyl-1H-benzimidazol-2-yl)methyl]-N2-phenyl-1,2-ethanediamine104295-10-5C19H24N4
- 2-[[[4-(Ethoxyiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazole-5-carboxylic Acid Ethyl Ester Hydrochloride1427571-33-2C21H25ClN4O3
- YG52Fbs38E91362-51-5C14H14N4
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1nc2ccccc2s1)c1ccccc1122 chemicals
O=C(Nc1ccccc1)c1cc2ccccc2o164 chemicals
O=C(Nc1cc2c(s1)CCCC2)c1ccccc160 chemicals![Scaffold O=S(Cc1ccccn1)c1nc2ccccc2[nH]1](/scaffold/HBDKFZNDMVLSHM-UHFFFAOYSA-N/structure.svg)
O=S(Cc1ccccn1)c1nc2ccccc2[nH]154 chemicals![Scaffold C(=Cc1nc2ccccc2[nH]1)c1ccccc1](/scaffold/QQLPPRIZUPEKMV-UHFFFAOYSA-N/structure.svg)
C(=Cc1nc2ccccc2[nH]1)c1ccccc149 chemicals![Scaffold c1ccc(OCc2nc3ccccc3[nH]2)cc1](/scaffold/XATKRQREMKIRLA-UHFFFAOYSA-N/structure.svg)
c1ccc(OCc2nc3ccccc3[nH]2)cc147 chemicals![Scaffold O=c1[nH]c(=O)c2nc(SCc3ccccc3)[nH]c2[nH]1](/scaffold/DPACPINNZAEEGT-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2nc(SCc3ccccc3)[nH]c2[nH]138 chemicals![Scaffold O=C(Nc1nc2ccccc2[nH]1)c1ccccc1](/scaffold/LYLQJTSHZYGWBO-UHFFFAOYSA-N/structure.svg)
O=C(Nc1nc2ccccc2[nH]1)c1ccccc137 chemicals![Scaffold c1ccc(CSc2nc3ccccc3[nH]2)cc1](/scaffold/IJINDUSMSVDESS-UHFFFAOYSA-N/structure.svg)
c1ccc(CSc2nc3ccccc3[nH]2)cc134 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]c(NCc3ccccc3)nc2[nH]1](/scaffold/GWEJMPIBANKNEQ-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]c(NCc3ccccc3)nc2[nH]132 chemicals
O=C(Nc1ccccc1)c1cc2ccccc2s130 chemicals![Scaffold c1ccc(CNc2nc3ccccc3[nH]2)cc1](/scaffold/FXMPPQGQNSTUGE-UHFFFAOYSA-N/structure.svg)
c1ccc(CNc2nc3ccccc3[nH]2)cc128 chemicals