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Murcko scaffold

Ring system with 3 rings and 16 atoms

144 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
144
With full pages
16
Scaffold SMILES

c1ccc(Nc2ncnc3sccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2ncnc3sccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 144 chemicals

N-(2-Fluorophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine hydrochloride chemical structure, C14H13ClFN3S, CAS 1216412-66-6
N-(2-Fluorophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-amine hydrochloride
CAS 1216412-66-6C14H13ClFN3S
6-Methyl-N-(m-tolyl)thieno[2,3-d]pyrimidin-4-amine hydrochloride chemical structure, C14H14ClN3S, CAS 1216580-26-5
6-Methyl-N-(m-tolyl)thieno[2,3-d]pyrimidin-4-amine hydrochloride
CAS 1216580-26-5C14H14ClN3S
N-(4-Fluorophenyl)-6-methylthieno[2,3-d]pyrimidin-4-amine hydrochloride chemical structure, C13H11ClFN3S, CAS 1216629-38-7
N-(4-Fluorophenyl)-6-methylthieno[2,3-d]pyrimidin-4-amine hydrochloride
CAS 1216629-38-7C13H11ClFN3S
3-{[6-(Ethoxycarbonyl)-5-methylthieno[2,3-d]pyrimidin-4-yl]amino}benzoic acid hydrochloride chemical structure, C17H16ClN3O4S, CAS 1093851-14-9
3-{[6-(Ethoxycarbonyl)-5-methylthieno[2,3-d]pyrimidin-4-yl]amino}benzoic acid hydrochloride
CAS 1093851-14-9C17H16ClN3O4S
6-Ethyl-N-(4-methoxyphenyl)-2-methylthieno[2,3-d]pyrimidin-4-amine hydrochloride chemical structure, C16H18ClN3OS, CAS 1185108-03-5
6-Ethyl-N-(4-methoxyphenyl)-2-methylthieno[2,3-d]pyrimidin-4-amine hydrochloride
CAS 1185108-03-5C16H18ClN3OS
4-((2,5,6-Trimethylthieno[2,3-d]pyrimidin-4-yl)amino)benzoic acid hydrochloride chemical structure, C16H16ClN3O2S, CAS 1179373-94-4
4-((2,5,6-Trimethylthieno[2,3-d]pyrimidin-4-yl)amino)benzoic acid hydrochloride
CAS 1179373-94-4C16H16ClN3O2S
Methyl 3-((6-ethyl-2-methylthieno[2,3-d]pyrimidin-4-yl)amino)benzoate hydrochloride chemical structure, C17H18ClN3O2S, CAS 1185151-84-1
Methyl 3-((6-ethyl-2-methylthieno[2,3-d]pyrimidin-4-yl)amino)benzoate hydrochloride
CAS 1185151-84-1C17H18ClN3O2S
(3-Chloro-4-fluoro-phenyl)-(6-methyl-thieno[2,3-d]pyrimidin-4-yl)-amine chemical structure, C13H9ClFN3S, CAS 434914-75-7
(3-Chloro-4-fluoro-phenyl)-(6-methyl-thieno[2,3-d]pyrimidin-4-yl)-amine
CAS 434914-75-7C13H9ClFN3S
5-((6-Methylthieno[2,3-d]pyrimidin-4-yl)amino)isophthalic acid chemical structure, C15H11N3O4S, CAS 1081316-05-3
5-((6-Methylthieno[2,3-d]pyrimidin-4-yl)amino)isophthalic acid
CAS 1081316-05-3C15H11N3O4S
4-(4-Hydroxyanilino)-5-methylthieno[2,3-d]pyrimidine-6-carboxylic acid chemical structure, C14H11N3O3S, CAS 1082119-90-1
4-(4-Hydroxyanilino)-5-methylthieno[2,3-d]pyrimidine-6-carboxylic acid
CAS 1082119-90-1C14H11N3O3S
3-Ethoxy-4-((5-methylthieno[2,3-d]pyrimidin-4-yl)amino)benzamide chemical structure, C16H16N4O2S, CAS 917908-06-6
3-Ethoxy-4-((5-methylthieno[2,3-d]pyrimidin-4-yl)amino)benzamide
CAS 917908-06-6C16H16N4O2S
(6-Methylthieno[2,3-d]pyrimidin-4-yl)(4-trifluoromethoxyphenyl)amine chemical structure, C14H10F3N3OS, CAS 1160703-00-3
(6-Methylthieno[2,3-d]pyrimidin-4-yl)(4-trifluoromethoxyphenyl)amine
CAS 1160703-00-3C14H10F3N3OS
N-(3-(Dimethylamino)propyl)-4-((4-fluoro-2-isopropoxyphenyl)amino)-5-methylthieno[2,3-d]pyrimidine-6-carboxamide chemical structure, C22H28FN5O2S, CAS 1211758-28-9
N-(3-(Dimethylamino)propyl)-4-((4-fluoro-2-isopropoxyphenyl)amino)-5-methylthieno[2,3-d]pyrimidine-6-carboxamide
CAS 1211758-28-9C22H28FN5O2S
6-Ethyl-N-phenylthieno[2,3-d]pyrimidin-4-amine hydrochloride chemical structure, C14H14ClN3S, CAS 1217062-24-2
6-Ethyl-N-phenylthieno[2,3-d]pyrimidin-4-amine hydrochloride
CAS 1217062-24-2C14H14ClN3S
4-((4-Fluoro-2-isopropoxyphenyl)amino)-5-methylthieno(2,3-d)pyrimidine-6-carboxylic acid chemical structure, C17H16FN3O3S, CAS 1211757-83-3
4-((4-Fluoro-2-isopropoxyphenyl)amino)-5-methylthieno(2,3-d)pyrimidine-6-carboxylic acid
CAS 1211757-83-3C17H16FN3O3S
N-(4-Methoxyphenyl)-2-methylthieno[2,3-d]pyrimidin-4-amine chemical structure, C14H13N3OS, CAS 935843-45-1
N-(4-Methoxyphenyl)-2-methylthieno[2,3-d]pyrimidin-4-amine
CAS 935843-45-1C14H13N3OS
N-(4-Methoxyphenyl)-2,5-dimethylthieno[2,3-d]pyrimidin-4-amine hydrochloride chemical structure, C15H16ClN3OS, CAS 935843-37-1
N-(4-Methoxyphenyl)-2,5-dimethylthieno[2,3-d]pyrimidin-4-amine hydrochloride
CAS 935843-37-1C15H16ClN3OS
N-[2-(2-Bromoethoxy)phenyl]-5-methylthieno[2,3-d]pyrimidin-4-amine chemical structure, C15H14BrN3OS, CAS 917907-41-6
N-[2-(2-Bromoethoxy)phenyl]-5-methylthieno[2,3-d]pyrimidin-4-amine
CAS 917907-41-6C15H14BrN3OS
N-{2-[(Butan-2-yl)oxy]phenyl}-5-ethylthieno[2,3-d]pyrimidin-4-amine chemical structure, C18H21N3OS, CAS 917907-87-0
N-{2-[(Butan-2-yl)oxy]phenyl}-5-ethylthieno[2,3-d]pyrimidin-4-amine
CAS 917907-87-0C18H21N3OS
3-Ethoxy-4-[(5-methylthieno[2,3-d]pyrimidin-4-yl)amino]benzonitrile chemical structure, C16H14N4OS, CAS 917908-41-9
3-Ethoxy-4-[(5-methylthieno[2,3-d]pyrimidin-4-yl)amino]benzonitrile
CAS 917908-41-9C16H14N4OS
5-Amino-4-(3-chloro-4-fluoro-phenylamino)-thieno[2,3-d]pyrimidine-6-carboxylic acid chemical structure, C13H8ClFN4O2S, CAS 944414-78-2
5-Amino-4-(3-chloro-4-fluoro-phenylamino)-thieno[2,3-d]pyrimidine-6-carboxylic acid
CAS 944414-78-2C13H8ClFN4O2S
N-(2-Ethoxy-4-fluorophenyl)thieno[2,3-d]pyrimidin-4-amine chemical structure, C14H12FN3OS, CAS 917907-48-3
N-(2-Ethoxy-4-fluorophenyl)thieno[2,3-d]pyrimidin-4-amine
CAS 917907-48-3C14H12FN3OS
N-(2,6-Dimethoxyphenyl)thieno[2,3-d]pyrimidin-4-amine chemical structure, C14H13N3O2S, CAS 917907-38-1
N-(2,6-Dimethoxyphenyl)thieno[2,3-d]pyrimidin-4-amine
CAS 917907-38-1C14H13N3O2S
N-[2-(3-Ethoxypropoxy)phenyl]thieno[2,3-D]pyrimidin-4-amine chemical structure, C17H19N3O2S, CAS 917907-04-1
N-[2-(3-Ethoxypropoxy)phenyl]thieno[2,3-D]pyrimidin-4-amine
CAS 917907-04-1C17H19N3O2S