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Murcko scaffold

Ring system with 2 rings and 17 atoms

202 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
202
With full pages
31
Scaffold SMILES

O=C(NC=Cc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC=Cc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 202 chemicals

Ethyl 2-benzamido-3-[2-(hydroxyamino)phenyl]prop-2-enoate chemical structure, C18H18N2O4, CAS 5009-43-8
Ethyl 2-benzamido-3-[2-(hydroxyamino)phenyl]prop-2-enoate
CAS 5009-43-8C18H18N2O4
alpha-Benzamido-4-hydroxy-3-methoxy-cinnamic acid chemical structure, C17H15NO5, CAS 35150-10-8
alpha-Benzamido-4-hydroxy-3-methoxy-cinnamic acid
CAS 35150-10-8C17H15NO5
N-[1-(2,4-Dichlorophenyl)-3-(hexylamino)-3-oxoprop-1-en-2-yl]benzamide chemical structure, C22H24Cl2N2O2, CAS 6651-16-7
N-[1-(2,4-Dichlorophenyl)-3-(hexylamino)-3-oxoprop-1-en-2-yl]benzamide
CAS 6651-16-7C22H24Cl2N2O2
N-[1-(4-Chlorophenyl)-3-hydrazinyl-3-oxoprop-1-en-2-yl]benzamide chemical structure, C16H14ClN3O2, CAS 6092-74-6
N-[1-(4-Chlorophenyl)-3-hydrazinyl-3-oxoprop-1-en-2-yl]benzamide
CAS 6092-74-6C16H14ClN3O2
2-Propenoic acid, 2-(benzoylamino)-3-(4-hydroxyphenyl)-, (Z)- chemical structure, C16H13NO4, CAS 64896-32-8
2-Propenoic acid, 2-(benzoylamino)-3-(4-hydroxyphenyl)-, (Z)-
CAS 64896-32-8C16H13NO4
2-(Benzoylamino)-3-(4-methoxyphenyl)acrylic acid chemical structure, C17H15NO4, CAS 93634-56-1
2-(Benzoylamino)-3-(4-methoxyphenyl)acrylic acid
CAS 93634-56-1C17H15NO4
3-(4-Chlorophenyl)-2-((4-methylbenzoyl)amino)acrylic acid chemical structure, C17H14ClNO3, CAS 300669-64-1
3-(4-Chlorophenyl)-2-((4-methylbenzoyl)amino)acrylic acid
CAS 300669-64-1C17H14ClNO3
2-Propenoic acid, 2-(benzoylamino)-3-(4-fluorophenyl)- chemical structure, C16H12FNO3, CAS 587-76-8
2-Propenoic acid, 2-(benzoylamino)-3-(4-fluorophenyl)-
CAS 587-76-8C16H12FNO3
N-[2-(3,4-Dimethoxyphenyl)-1-(hydrazinecarbonyl)eth-1-en-1-yl]benzamide chemical structure, C18H19N3O4, CAS 143417-45-2
N-[2-(3,4-Dimethoxyphenyl)-1-(hydrazinecarbonyl)eth-1-en-1-yl]benzamide
CAS 143417-45-2C18H19N3O4
N-[1-Carbamoyl-2-(4-dimethylamino-phenyl)-vinyl]-benzamide chemical structure, C18H19N3O2, CAS 70985-06-7
N-[1-Carbamoyl-2-(4-dimethylamino-phenyl)-vinyl]-benzamide
CAS 70985-06-7C18H19N3O2
(2E)-2-(Benzoylamino)-3-phenyl-2-propenoic acid chemical structure, C16H13NO3, CAS 57427-85-7
(2E)-2-(Benzoylamino)-3-phenyl-2-propenoic acid
CAS 57427-85-7C16H13NO3
2-Propenoic acid, 2-(benzoylamino)-3-(3-nitrophenyl)-, (Z)- chemical structure, C16H12N2O5, CAS 89267-00-5
2-Propenoic acid, 2-(benzoylamino)-3-(3-nitrophenyl)-, (Z)-
CAS 89267-00-5C16H12N2O5
N-[(E)-3-Amino-1-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]benzamide chemical structure, C17H16N2O3, CAS 70985-02-3
N-[(E)-3-Amino-1-(4-methoxyphenyl)-3-oxoprop-1-en-2-yl]benzamide
CAS 70985-02-3C17H16N2O3
2-(Benzoylamino)-3-[4-(dimethylamino)phenyl]-acrylic acid chemical structure, C18H18N2O3, CAS 3626-95-7
2-(Benzoylamino)-3-[4-(dimethylamino)phenyl]-acrylic acid
CAS 3626-95-7C18H18N2O3
(E)-2-(2,4-Dichlorobenzamido)-3-phenylacrylic acid chemical structure, C16H11Cl2NO3, CAS 315707-49-4
(E)-2-(2,4-Dichlorobenzamido)-3-phenylacrylic acid
CAS 315707-49-4C16H11Cl2NO3
2-Chloro-N-{(1Z)-1-[4-(diethylamino)phenyl]-3-hydrazinyl-3-oxoprop-1-en-2-yl}benzamide chemical structure, C20H23ClN4O2, CAS 322665-59-8
2-Chloro-N-{(1Z)-1-[4-(diethylamino)phenyl]-3-hydrazinyl-3-oxoprop-1-en-2-yl}benzamide
CAS 322665-59-8C20H23ClN4O2
N-{(1Z)-1-[4-(diethylamino)phenyl]-3-hydrazinyl-3-oxoprop-1-en-2-yl}benzamide chemical structure, C20H24N4O2, CAS 30530-25-7
N-{(1Z)-1-[4-(diethylamino)phenyl]-3-hydrazinyl-3-oxoprop-1-en-2-yl}benzamide
CAS 30530-25-7C20H24N4O2
N-[(E)-3-Amino-1-(3-nitrophenyl)-3-oxoprop-1-en-2-yl]-4-bromobenzamide chemical structure, C16H12BrN3O4, CAS 431069-06-6
N-[(E)-3-Amino-1-(3-nitrophenyl)-3-oxoprop-1-en-2-yl]-4-bromobenzamide
CAS 431069-06-6C16H12BrN3O4
(2E)-3-(4-Methoxyphenyl)-2-[(3,4,5-trimethoxybenzoyl)amino]acrylic acid chemical structure, C20H21NO7, CAS 312913-69-2
(2E)-3-(4-Methoxyphenyl)-2-[(3,4,5-trimethoxybenzoyl)amino]acrylic acid
CAS 312913-69-2C20H21NO7
(2E)-3-[4-(Dimethylamino)phenyl]-2-{[(3,4,5-trimethoxyphenyl)carbonyl]amino}prop-2-enoic acid chemical structure, C21H24N2O6, CAS 5689-63-4
(2E)-3-[4-(Dimethylamino)phenyl]-2-{[(3,4,5-trimethoxyphenyl)carbonyl]amino}prop-2-enoic acid
CAS 5689-63-4C21H24N2O6
(E)-3-(2-Methoxyphenyl)-2-(3,4,5-trimethoxybenzamido)acrylic acid chemical structure, C20H21NO7, CAS 375836-09-2
(E)-3-(2-Methoxyphenyl)-2-(3,4,5-trimethoxybenzamido)acrylic acid
CAS 375836-09-2C20H21NO7
(E)-2-(2,4-Dichlorobenzamido)-3-(4-(dimethylamino)phenyl)acrylic acid chemical structure, C18H16Cl2N2O3, CAS 423754-16-9
(E)-2-(2,4-Dichlorobenzamido)-3-(4-(dimethylamino)phenyl)acrylic acid
CAS 423754-16-9C18H16Cl2N2O3
(E)-2-Benzamido-3-(2,4-dimethoxyphenyl)prop-2-enoic acid chemical structure, C18H17NO5, CAS 7149-95-3
(E)-2-Benzamido-3-(2,4-dimethoxyphenyl)prop-2-enoic acid
CAS 7149-95-3C18H17NO5
(Z)-2-Benzamido-3-(2,4-dimethoxyphenyl)acrylic acid chemical structure, C18H17NO5, CAS 119872-11-6
(Z)-2-Benzamido-3-(2,4-dimethoxyphenyl)acrylic acid
CAS 119872-11-6C18H17NO5