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Murcko scaffold

Ring system with 2 rings and 14 atoms

6 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
6
With full pages
4
Scaffold SMILES

O=c1[nH]cc(C=Nc2ccccc2)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cc(C=Nc2ccccc2)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

5-[(4-Bromoanilino)methylidene]-3-methylthiazolidine-2,4-dione chemical structure, C11H9BrN2O2S, CAS 478081-27-5
5-[(4-Bromoanilino)methylidene]-3-methylthiazolidine-2,4-dione
CAS 478081-27-5C11H9BrN2O2S
5-((4-Bromoanilino)methylene)-1,3-thiazolidine-2,4-dione chemical structure, C10H7BrN2O2S, CAS 308095-89-8
5-((4-Bromoanilino)methylene)-1,3-thiazolidine-2,4-dione
CAS 308095-89-8C10H7BrN2O2S
5-(2-Toluidinomethylene)-1,3-thiazolidine-2,4-dione chemical structure, C11H10N2O2S, CAS 308095-91-2
5-(2-Toluidinomethylene)-1,3-thiazolidine-2,4-dione
CAS 308095-91-2C11H10N2O2S
5-{(Z)-[4-(tert-Butyl)anilino]methylidene}-3-methyl-1,3-thiazolane-2,4-dione chemical structure, C15H18N2O2S, CAS 866131-82-0
5-{(Z)-[4-(tert-Butyl)anilino]methylidene}-3-methyl-1,3-thiazolane-2,4-dione
CAS 866131-82-0C15H18N2O2S
5-((4-Ethoxyanilino)methylene)-1,3-thiazolidine-2,4-dione chemical structure, C12H12N2O3S, CAS 308095-93-4
5-((4-Ethoxyanilino)methylene)-1,3-thiazolidine-2,4-dione
CAS 308095-93-4C12H12N2O3S
5-[(Phenylamino)methylene]-3-(2-propen-1-yl)-2,4-thiazolidinedione chemical structure, C13H12N2O2S, CAS 857041-68-0
5-[(Phenylamino)methylene]-3-(2-propen-1-yl)-2,4-thiazolidinedione
CAS 857041-68-0C13H12N2O2S