Murcko scaffold
Ring system with 2 rings and 13 atoms
45 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 13
- Chemicals
- 45
- With full pages
- 3
Scaffold SMILES
O=C(C1CCCC1)N1CCCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 45 of 45 chemicals
1,2,2-Trimethyl-3-(piperidine-1-carbonyl)-cyclopentanecarboxylic acid
CAS 97100-98-6C15H25NO3
Cyclopentyl(2-ethylpiperidin-1-yl)methanone
CAS 574718-40-4C13H23NO
Cyclopentyl-(3,5-dimethylpiperidin-1-yl)methanone
CAS 574008-98-3C13H23NO
1-Cyclopentanecarbonylpiperidine-2-carboxylic acid
CAS 1044637-65-1C12H19NO3
1-(Cyclopentylcarbonyl)piperidine-3-carboxylic acid
CAS 926227-70-5C12H19NO3
1-(Cyclopentanecarbonyl)piperidine-4-carboxylic acid
CAS 147636-33-7C12H19NO3
(4-Aminopiperidin-1-yl)(cyclopentyl)methanone
CAS 926234-06-2C11H20N2O
Methyl 1-cyclopentanecarbonylpiperidine-4-carboxylate
CAS 1090337-46-4C13H21NO3
tert-Butyl 1-(cyclopentanecarbonyl)piperidin-4-ylcarbamate
CAS 1152430-24-4C16H28N2O3
Cyclopentyl(4-hydroxypiperidin-1-yl)methanone
CAS 1090829-61-0C11H19NO2
1-Cyclopentanecarbonylpiperidin-3-ol
CAS 1155000-14-8C11H19NO2
Cyclopentyl(3-(hydroxymethyl)piperidin-1-yl)methanone
CAS 1156804-84-0C12H21NO2
(4-Aminopiperidin-1-yl)(cyclopentyl)methanone hydrochloride
CAS 1269397-20-7C11H21ClN2O
Cyclopentyl(4-methoxypiperidin-1-yl)methanone
CAS 1340684-15-2C12H21NO2
1-Cyclopentanecarbonylpiperidine-3-sulfonamide
CAS 1308359-49-0C11H20N2O3S
Cyclopentyl(4-(hydroxymethyl)piperidin-1-yl)methanone
CAS 1178658-39-3C12H21NO2
(3-Aminopiperidin-1-yl)(cyclopentyl)methanone
CAS 1248317-53-4C11H20N2O
(4-(Aminomethyl)piperidin-1-yl)(cyclopentyl)methanone
CAS 1248120-38-8C12H22N2O
(3-(Aminomethyl)piperidin-1-yl)(cyclopentyl)methanone
CAS 1250657-92-1C12H22N2O
Cyclopentyl(3-(methylamino)piperidin-1-yl)methanone
CAS 1250312-60-7C12H22N2O
1-Cyclopentanecarbonyl-4-methyl-piperidine-4-carboxylic acid
CAS 1280593-36-3C13H21NO3
1-Cyclopentanecarbonyl-4-methylpiperidin-3-amine
CAS 1342758-27-3C12H22N2O
1-Cyclopentanecarbonylpiperidine-3-carbonitrile
CAS 1496910-89-4C12H18N2O
(2-(Aminomethyl)cyclopentyl)(4-hydroxypiperidin-1-yl)methanone
CAS 1496880-47-7C12H22N2O2
- 3-(Piperidine-1-carbonyl)cyclopentan-1-amine1496871-83-0C11H20N2O
- Cyclopentyl(4-(methylsulfonyl)piperidin-1-yl)methanone1448046-59-0C12H21NO3S
- 1-Cyclopentanecarbonylpiperidine-3-sulfonyl chloride1461705-97-4C11H18ClNO3S
- 2-(1-(Cyclopentanecarbonyl)piperidin-4-yl)acetic acid1484760-45-3C13H21NO3
- 3-(Piperidine-1-carbonyl)cyclopentanecarboxylic acid1694540-25-4C12H19NO3
- (1S,3R)-3-(Piperidine-1-carbonyl)cyclopentan-1-amine1807940-78-8C11H20N2O
- (3R)-1-Cyclopentanecarbonylpiperidin-3-amine1704940-56-6C11H20N2O
- (R)-Cyclopentyl(3-(methylamino)piperidin-1-yl)methanone hydrochloride3078596-29-6C12H23ClN2O
- Cyclopentyl(4-((methylamino)methyl)piperidin-1-yl)methanone hydrochloride1576230-71-1C13H25ClN2O
- Cyclopentyl(4-(2-hydroxyethyl)piperidin-1-yl)methanone2006219-71-0C13H23NO2
- Rac-(1r,3s)-3-(piperidine-1-carbonyl)cyclopentan-1-amine1932630-38-0C11H20N2O
- 2-(1-Cyclopentanecarbonylpiperidin-3-yl)propan-2-ol2138244-55-8C14H25NO2
- 1-Cyclopentanecarbonyl-4-ethylpiperidin-3-amine2137564-77-1C13H24N2O
- 1-Cyclopentanecarbonyl-4-(2-methylpropyl)piperidin-3-amine2137705-66-7C15H28N2O
- 1-Cyclopentanecarbonylpiperidine-3-sulfinyl chloride2138176-12-0C11H18ClNO2S
- Sodium 1-cyclopentanecarbonylpiperidine-3-sulfinate2137982-55-7C11H18NNaO3S
- [1-Cyclopentanecarbonyl-4-(hydroxymethyl)piperidin-4-yl]methanol2138255-80-6C13H23NO3
- 1-Cyclopentanecarbonylpiperidine-3-sulfonyl fluoride2138183-02-3C11H18FNO3S
- 1-Cyclopentanecarbonylpiperidine-3-sulfinamide2137681-75-3C11H20N2O2S
- 4-((tert-Butoxycarbonyl)amino)-1-(cyclopentanecarbonyl)piperidine-4-carboxylic acid3078580-77-2C17H28N2O5
- cis-3-Aminocyclopentyl)(4,4-difluoropiperidin-1-yl)methanone hydrochloride2931243-42-2C11H19ClF2N2O
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cn2cccn2)cc1271 chemicals
c1ccc(CN2CCCC2)cc1172 chemicals
O=S(=O)(c1ccccc1)N1CCCC1146 chemicals
c1ccc(Cn2ccnc2)cc1107 chemicals![Scaffold c1ccc(N=c2[nH]ccs2)cc1](/scaffold/OGVGQYZRJXSMGC-UHFFFAOYSA-N/structure.svg)
c1ccc(N=c2[nH]ccs2)cc198 chemicals
O=C1NC(=S)SC1=Cc1ccccc186 chemicals
O=C(c1ccccc1)N1CCCC186 chemicals
O=S(=O)(c1ccccc1)n1ccnc184 chemicals![Scaffold O=C(c1ccccc1)c1cc[nH]c1](/scaffold/DSNSKSWTLGZGAN-UHFFFAOYSA-N/structure.svg)
O=C(c1ccccc1)c1cc[nH]c177 chemicals
c1ccc(Cn2ccnn2)cc177 chemicals
c1ccc(Cc2cncs2)cc175 chemicals
c1ccc(Cn2cccc2)cc163 chemicals