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Murcko scaffold

Ring system with 3 rings and 16 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
12
With full pages
3
Scaffold SMILES

O=C1Nc2ccccc2C2(CCCNC2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1Nc2ccccc2C2(CCCNC2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

6-Chlorospiro[benzo[d][1,3]oxazine-4,3'-piperidin]-2(1H)-one chemical structure, C12H13ClN2O2, CAS 1892807-75-8
6-Chlorospiro[benzo[d][1,3]oxazine-4,3'-piperidin]-2(1H)-one
CAS 1892807-75-8C12H13ClN2O2
(R)-6-Chlorospiro[benzo[d][1,3]oxazine-4,3'-piperidin]-2(1H)-one chemical structure, C12H13ClN2O2, CAS 1821026-92-9
(R)-6-Chlorospiro[benzo[d][1,3]oxazine-4,3'-piperidin]-2(1H)-one
CAS 1821026-92-9C12H13ClN2O2
(R)-6-Chlorospiro[benzo[d][1,3]oxazine-4,3'-piperidin]-2(1H)-one hydrochloride chemical structure, C12H14Cl2N2O2, CAS 1821026-93-0
(R)-6-Chlorospiro[benzo[d][1,3]oxazine-4,3'-piperidin]-2(1H)-one hydrochloride
CAS 1821026-93-0C12H14Cl2N2O2
6-Chloro-5-fluoro-2'-methyl-1,2-dihydrospiro(3,1-benzoxazine-4,3'-piperidine)-2-one hydrochloride chemical structure, C13H15Cl2FN2O2, CAS 2228305-61-9
6-Chloro-5-fluoro-2'-methyl-1,2-dihydrospiro(3,1-benzoxazine-4,3'-piperidine)-2-one hydrochloride
CAS 2228305-61-9C13H15Cl2FN2O2
6-Chloro-5-fluoro-2'-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-piperidin]-2-one chemical structure, C13H14ClFN2O2, CAS 2228305-60-8
6-Chloro-5-fluoro-2'-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-piperidin]-2-one
CAS 2228305-60-8C13H14ClFN2O2
6-Chloro-5-fluoro-5'-methyl-1,2-dihydrospiro(3,1-benzoxazine-4,3'-piperidine)-2-one hydrochloride chemical structure, C13H15Cl2FN2O2, CAS 2225146-23-4
6-Chloro-5-fluoro-5'-methyl-1,2-dihydrospiro(3,1-benzoxazine-4,3'-piperidine)-2-one hydrochloride
CAS 2225146-23-4C13H15Cl2FN2O2
6-Chloro-5-fluoro-5'-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-piperidin]-2-one chemical structure, C13H14ClFN2O2, CAS 2225146-22-3
6-Chloro-5-fluoro-5'-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-piperidin]-2-one
CAS 2225146-22-3C13H14ClFN2O2
6-Chloro-5-fluoro-6'-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-piperidine]-2-one hydrochloride chemical structure, C13H15Cl2FN2O2, CAS 2225141-59-1
6-Chloro-5-fluoro-6'-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-piperidine]-2-one hydrochloride
CAS 2225141-59-1C13H15Cl2FN2O2
6-Chloro-5-fluoro-6'-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-piperidine]-2-one chemical structure, C13H14ClFN2O2, CAS 2225141-58-0
6-Chloro-5-fluoro-6'-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-piperidine]-2-one
CAS 2225141-58-0C13H14ClFN2O2
(5'R)-6-Chloro-5-fluoro-5'-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-piperidine]-2-one chemical structure, C13H14ClFN2O2, CAS 2248221-09-0
(5'R)-6-Chloro-5-fluoro-5'-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-piperidine]-2-one
CAS 2248221-09-0C13H14ClFN2O2
(5'S)-6-Chloro-5-fluoro-5'-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-piperidine]-2-one chemical structure, C13H14ClFN2O2, CAS 2248221-10-3
(5'S)-6-Chloro-5-fluoro-5'-methyl-1,2-dihydrospiro[3,1-benzoxazine-4,3'-piperidine]-2-one
CAS 2248221-10-3C13H14ClFN2O2
(S)-6-Chloro-5-fluorospiro[benzo[d][1,3]oxazine-4,3'-piperidin]-2(1H)-one chemical structure, C12H12ClFN2O2, CAS 2857081-39-9
(S)-6-Chloro-5-fluorospiro[benzo[d][1,3]oxazine-4,3'-piperidin]-2(1H)-one
CAS 2857081-39-9C12H12ClFN2O2