CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 15 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
5
With full pages
1
Scaffold SMILES

C1=CC2=CCNCC2C2(C1)CCNCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=CC2=CCNCC2C2(C1)CCNCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

6-Amino-1',2-dimethylspiro[3,8a-dihydro-1H-isoquinoline-8,4'-piperidine]-5,7,7-tricarbonitrile chemical structure, C18H22N6, CAS 328282-26-4
6-Amino-1',2-dimethylspiro[3,8a-dihydro-1H-isoquinoline-8,4'-piperidine]-5,7,7-tricarbonitrile
CAS 328282-26-4C18H22N6
6-Amino-1',2-dipropylspiro[3,8a-dihydro-1H-isoquinoline-8,4'-piperidine]-5,7,7-tricarbonitrile chemical structure, C22H30N6, CAS 312265-21-7
6-Amino-1',2-dipropylspiro[3,8a-dihydro-1H-isoquinoline-8,4'-piperidine]-5,7,7-tricarbonitrile
CAS 312265-21-7C22H30N6
Ditert-butyl 6-amino-5,7,7-tricyanospiro[3,8a-dihydro-1H-isoquinoline-8,4'-piperidine]-1',2-dicarboxylate chemical structure, C26H34N6O4, CAS 302588-89-2
Ditert-butyl 6-amino-5,7,7-tricyanospiro[3,8a-dihydro-1H-isoquinoline-8,4'-piperidine]-1',2-dicarboxylate
CAS 302588-89-2C26H34N6O4
Diethyl 6-amino-5,7,7-tricyanospiro[3,8a-dihydro-1H-isoquinoline-8,4'-piperidine]-1',2-dicarboxylate chemical structure, C22H26N6O4, CAS 353462-57-4
Diethyl 6-amino-5,7,7-tricyanospiro[3,8a-dihydro-1H-isoquinoline-8,4'-piperidine]-1',2-dicarboxylate
CAS 353462-57-4C22H26N6O4
6-Amino-1',2-diethylspiro[3,8a-dihydro-1H-isoquinoline-8,4'-piperidine]-5,7,7-tricarbonitrile chemical structure, C20H26N6, CAS 300731-01-5
6-Amino-1',2-diethylspiro[3,8a-dihydro-1H-isoquinoline-8,4'-piperidine]-5,7,7-tricarbonitrile
CAS 300731-01-5C20H26N6