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Murcko scaffold

Ring system with 3 rings and 16 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
7
With full pages
5
Scaffold SMILES

O=C1CCCC2=C1C1(C=CO2)CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCC2=C1C1(C=CO2)CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

2-Amino-3-cyano-1'-ethoxycarbonyl-5-oxo-5,6,7,8-tetrahydrospiro[4H-chromene-4,4'-piperidine] chemical structure, C17H21N3O4, CAS 309278-18-0
2-Amino-3-cyano-1'-ethoxycarbonyl-5-oxo-5,6,7,8-tetrahydrospiro[4H-chromene-4,4'-piperidine]
CAS 309278-18-0C17H21N3O4
1'-Acetyl-2-amino-7,7-dimethyl-5-oxospiro[6,8-dihydrochromene-4,4'-piperidine]-3-carbonitrile chemical structure, C18H23N3O3, CAS 309278-17-9
1'-Acetyl-2-amino-7,7-dimethyl-5-oxospiro[6,8-dihydrochromene-4,4'-piperidine]-3-carbonitrile
CAS 309278-17-9C18H23N3O3
Ethyl 2-amino-3-cyano-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydrospiro[chromene-4,4'-piperidine]-1'-carboxylate chemical structure, C19H25N3O4, CAS 340812-17-1
Ethyl 2-amino-3-cyano-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydrospiro[chromene-4,4'-piperidine]-1'-carboxylate
CAS 340812-17-1C19H25N3O4
1'-Acetyl-2-amino-5-oxospiro[7,8-dihydro-6H-chromene-4,4'-piperidine]-3-carbonitrile chemical structure, C16H19N3O3, CAS 340812-58-0
1'-Acetyl-2-amino-5-oxospiro[7,8-dihydro-6H-chromene-4,4'-piperidine]-3-carbonitrile
CAS 340812-58-0C16H19N3O3
tert-Butyl 2-amino-3-cyano-5-oxospiro[7,8-dihydro-6H-chromene-4,4'-piperidine]-1'-carboxylate chemical structure, C19H25N3O4, CAS 340812-59-1
tert-Butyl 2-amino-3-cyano-5-oxospiro[7,8-dihydro-6H-chromene-4,4'-piperidine]-1'-carboxylate
CAS 340812-59-1C19H25N3O4
Ethyl 2-amino-3-cyano-7-methyl-5-oxospiro[7,8-dihydro-6H-chromene-4,4'-piperidine]-1'-carboxylate chemical structure, C18H23N3O4, CAS 445390-97-6
Ethyl 2-amino-3-cyano-7-methyl-5-oxospiro[7,8-dihydro-6H-chromene-4,4'-piperidine]-1'-carboxylate
CAS 445390-97-6C18H23N3O4
1'-Acetyl-2-amino-7-methyl-5-oxo-5,6,7,8-tetrahydrospiro[chromene-4,4'-piperidine]-3-carbonitrile chemical structure, C17H21N3O3, CAS 625369-39-3
1'-Acetyl-2-amino-7-methyl-5-oxo-5,6,7,8-tetrahydrospiro[chromene-4,4'-piperidine]-3-carbonitrile
CAS 625369-39-3C17H21N3O3