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Murcko scaffold

2,3-Dihydro-1H-spiro[isoquinoline-4,4'-piperidine] scaffold

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
14
With full pages
2
Scaffold SMILES

c1ccc2c(c1)CNCC21CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3-Dihydro-1H-spiro[isoquinoline-4,4'-piperidine] page
Murcko scaffold c1ccc2c(c1)CNCC21CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

1-{2,3-Dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-2-yl}ethan-1-one chemical structure, C15H20N2O, CAS 159634-82-9
1-{2,3-Dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-2-yl}ethan-1-one
CAS 159634-82-9C15H20N2O
2,3-Dihydro-1H-spiro[isoquinoline-4,4'-piperidine] chemical structure, C13H18N2, CAS 1145670-30-9
2,3-Dihydro-1H-spiro[isoquinoline-4,4'-piperidine]
CAS 1145670-30-9C13H18N2
tert-Butyl 2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate chemical structure, C18H26N2O2, CAS 159634-80-7
tert-Butyl 2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate
CAS 159634-80-7C18H26N2O2
tert-Butyl 2,3-dihydro-1H-spiro(isoquinoline-4,4'-piperidine)-2-carboxylate hydrochloride chemical structure, C18H27ClN2O2, CAS 889139-52-0
tert-Butyl 2,3-dihydro-1H-spiro(isoquinoline-4,4'-piperidine)-2-carboxylate hydrochloride
CAS 889139-52-0C18H27ClN2O2
tert-Butyl 1H-spiro[isoquinoline-4,4'-piperidine]-2(3H)-carboxylate chemical structure, C18H26N2O2, CAS 857898-70-5
tert-Butyl 1H-spiro[isoquinoline-4,4'-piperidine]-2(3H)-carboxylate
CAS 857898-70-5C18H26N2O2
tert-Butyl 2-acetyl-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate chemical structure, C20H28N2O3, CAS 159634-81-8
tert-Butyl 2-acetyl-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate
CAS 159634-81-8C20H28N2O3
2,3-Dihydro-1H-spiro[isoquinoline-4,4'-piperidine] dihydrochloride chemical structure, C13H20Cl2N2, CAS 1588441-25-1
2,3-Dihydro-1H-spiro[isoquinoline-4,4'-piperidine] dihydrochloride
CAS 1588441-25-1C13H20Cl2N2
tert-Butyl 2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate hydrochloride chemical structure, C18H27ClN2O2, CAS 1279861-05-0
tert-Butyl 2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate hydrochloride
CAS 1279861-05-0C18H27ClN2O2
2,3-Dihydro-1H-spiro[isoquinoline-4,4'-piperidine] hydrochloride chemical structure, C13H19ClN2, CAS 1956355-73-9
2,3-Dihydro-1H-spiro[isoquinoline-4,4'-piperidine] hydrochloride
CAS 1956355-73-9C13H19ClN2
1'-Methyl-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine] chemical structure, C14H20N2, CAS 109473-40-7
1'-Methyl-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]
CAS 109473-40-7C14H20N2
tert-Butyl 7-methyl-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate chemical structure, C19H28N2O2, CAS 906369-89-9
tert-Butyl 7-methyl-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate
CAS 906369-89-9C19H28N2O2
1'-Methyl-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine] dihydrochloride chemical structure, C14H22Cl2N2, CAS 2089256-02-8
1'-Methyl-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine] dihydrochloride
CAS 2089256-02-8C14H22Cl2N2
tert-Butyl 7-fluoro-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate chemical structure, C18H25FN2O2, CAS 1290627-44-9
tert-Butyl 7-fluoro-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1'-carboxylate
CAS 1290627-44-9C18H25FN2O2
tert-Butyl 7-methoxy-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1-carboxylate chemical structure, C19H28N2O3, CAS 2306261-79-8
tert-Butyl 7-methoxy-2,3-dihydro-1H-spiro[isoquinoline-4,4'-piperidine]-1-carboxylate
CAS 2306261-79-8C19H28N2O3