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Murcko scaffold

6-Phenylmorpholin-3-one scaffold

224 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
224
With full pages
3
Scaffold SMILES

O=C1COC(c2ccccc2)CN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Phenylmorpholin-3-one page
Murcko scaffold O=C1COC(c2ccccc2)CN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 224 chemicals

5-Methyl-6-phenyl-3-morpholinone chemical structure, C11H13NO2, CAS 5588-29-4
5-Methyl-6-phenyl-3-morpholinone
CAS 5588-29-4C11H13NO2
Flumetramide chemical structure, C11H10F3NO2, CAS 7125-73-7
Flumetramide
CAS 7125-73-7C11H10F3NO2
6-(4-Chlorophenyl)morpholin-3-one chemical structure, C10H10ClNO2, CAS 5196-95-2
6-(4-Chlorophenyl)morpholin-3-one
CAS 5196-95-2C10H10ClNO2
(R)-6-(4-Chlorophenyl)morpholin-3-one chemical structure, C10H10ClNO2, CAS 2381846-69-9
(R)-6-(4-Chlorophenyl)morpholin-3-one
CAS 2381846-69-9C10H10ClNO2
(S)-6-(4-Chlorophenyl)morpholin-3-one chemical structure, C10H10ClNO2, CAS 2988174-80-5
(S)-6-(4-Chlorophenyl)morpholin-3-one
CAS 2988174-80-5C10H10ClNO2
(±)-Cis-5-methyl-3-oxo-6-phenylmorpholine chemical structure, C11H13NO2, CAS 180683-53-8
(±)-Cis-5-methyl-3-oxo-6-phenylmorpholine
CAS 180683-53-8C11H13NO2
6-(4-Bromo-2,5-dimethoxyphenyl)morpholin-3-one chemical structure, C12H14BrNO4, CAS 807631-06-7
6-(4-Bromo-2,5-dimethoxyphenyl)morpholin-3-one
CAS 807631-06-7C12H14BrNO4
6-Phenylmorpholin-3-one chemical structure, C10H11NO2, CAS 5493-95-8
6-Phenylmorpholin-3-one
CAS 5493-95-8C10H11NO2
6-(4-Nitrophenyl)morpholin-3-one chemical structure, C10H10N2O4, CAS 70547-99-8
6-(4-Nitrophenyl)morpholin-3-one
CAS 70547-99-8C10H10N2O4
(5S,6S)-5-Methyl-6-phenylmorpholin-3-one chemical structure, C11H13NO2, CAS 5493-94-7
(5S,6S)-5-Methyl-6-phenylmorpholin-3-one
CAS 5493-94-7C11H13NO2
6-Ethyl-6-(3-methoxyphenyl)-4-methyl-2-(prop-2-en-1-yl)morpholin-3-one chemical structure, C17H23NO3, CAS 94703-66-9
6-Ethyl-6-(3-methoxyphenyl)-4-methyl-2-(prop-2-en-1-yl)morpholin-3-one
CAS 94703-66-9C17H23NO3
4,5-Dimethyl-6-phenyl-3-morpholinone chemical structure, C12H15NO2, CAS 5493-96-9
4,5-Dimethyl-6-phenyl-3-morpholinone
CAS 5493-96-9C12H15NO2
2-(3,4-Dimethoxyphenyl)morpholin-5-one chemical structure, C12H15NO4, CAS 204014-67-5
2-(3,4-Dimethoxyphenyl)morpholin-5-one
CAS 204014-67-5C12H15NO4
(6S)-6-(4-Fluorophenyl)-4-methylmorpholin-3-one chemical structure, C11H12FNO2, CAS 920798-06-7
(6S)-6-(4-Fluorophenyl)-4-methylmorpholin-3-one
CAS 920798-06-7C11H12FNO2
(6S)-4-Ethyl-6-(4-fluorophenyl)morpholin-3-one chemical structure, C12H14FNO2, CAS 920798-07-8
(6S)-4-Ethyl-6-(4-fluorophenyl)morpholin-3-one
CAS 920798-07-8C12H14FNO2
(6S)-4-tert-Butyl-6-(4-fluorophenyl)morpholin-3-one chemical structure, C14H18FNO2, CAS 920798-08-9
(6S)-4-tert-Butyl-6-(4-fluorophenyl)morpholin-3-one
CAS 920798-08-9C14H18FNO2
(6S)-6-(4-Fluorophenyl)-4-(prop-2-en-1-yl)morpholin-3-one chemical structure, C13H14FNO2, CAS 920798-09-0
(6S)-6-(4-Fluorophenyl)-4-(prop-2-en-1-yl)morpholin-3-one
CAS 920798-09-0C13H14FNO2
(6S)-6-(4-Fluorophenyl)morpholin-3-one chemical structure, C10H10FNO2, CAS 920798-10-3
(6S)-6-(4-Fluorophenyl)morpholin-3-one
CAS 920798-10-3C10H10FNO2
4-Methyl-6-phenylmorpholin-3-one chemical structure, C11H13NO2, CAS 92616-12-1
4-Methyl-6-phenylmorpholin-3-one
CAS 92616-12-1C11H13NO2
6-(4-Aminophenyl)-N-methylmorpholin-3-one chemical structure, C11H14N2O2, CAS 643087-11-0
6-(4-Aminophenyl)-N-methylmorpholin-3-one
CAS 643087-11-0C11H14N2O2
6-(4-Methoxyphenyl)morpholin-3-one chemical structure, C11H13NO3, CAS 5196-94-1
6-(4-Methoxyphenyl)morpholin-3-one
CAS 5196-94-1C11H13NO3
6-(3-Methoxyphenyl)morpholin-3-one chemical structure, C11H13NO3, CAS 947691-87-4
6-(3-Methoxyphenyl)morpholin-3-one
CAS 947691-87-4C11H13NO3
6-(2-Methoxyphenyl)morpholin-3-one chemical structure, C11H13NO3, CAS 951626-74-7
6-(2-Methoxyphenyl)morpholin-3-one
CAS 951626-74-7C11H13NO3
6-(o-Tolyl)morpholin-3-one chemical structure, C11H13NO2, CAS 951627-11-5
6-(o-Tolyl)morpholin-3-one
CAS 951627-11-5C11H13NO2