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Murcko scaffold

Ring system with 2 rings and 11 atoms

64 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
64
With full pages
14
Scaffold SMILES

O=S1(=O)CCCc2ccsc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S1(=O)CCCc2ccsc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 64 chemicals

4H-Thieno(2,3-b)thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide chemical structure, C10H16N2O4S3, CAS 120280-13-9
4H-Thieno(2,3-b)thiopyran-2-sulfonamide, 4-(ethylamino)-5,6-dihydro-6-methyl-, 7,7-dioxide
CAS 120280-13-9C10H16N2O4S3
Sezolamide hydrochloride chemical structure, C11H19ClN2O4S3, CAS 119271-78-2
Sezolamide hydrochloride
CAS 119271-78-2C11H19ClN2O4S3
Sezolamide chemical structure, C11H18N2O4S3, CAS 123308-22-5
Sezolamide
CAS 123308-22-5C11H18N2O4S3
(4R,6R)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide monohydrochloride chemical structure, C10H17ClN2O4S3, CAS 122028-36-8
(4R,6R)-4-(Ethylamino)-5,6-dihydro-6-methyl-4H-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide monohydrochloride
CAS 122028-36-8C10H17ClN2O4S3
5,6-Dihydro-6-methyl-4H-thieno(2,3-b)thiopyran-4-ol 7,7-dioxide, (4S,6S)- chemical structure, C8H10O3S2, CAS 147086-81-5
5,6-Dihydro-6-methyl-4H-thieno(2,3-b)thiopyran-4-ol 7,7-dioxide, (4S,6S)-
CAS 147086-81-5C8H10O3S2
(4R,6R)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide chemical structure, C10H16N2O4S3, CAS 1202579-95-0
(4R,6R)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
CAS 1202579-95-0C10H16N2O4S3
4-(2-Methylpropylamino)-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide chemical structure, C11H18N2O4S3, CAS 123291-07-6
4-(2-Methylpropylamino)-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide
CAS 123291-07-6C11H18N2O4S3
4-(Isobutylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride chemical structure, C11H19ClN2O4S3, CAS 126453-94-9
4-(Isobutylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride
CAS 126453-94-9C11H19ClN2O4S3
N-Deethyldorzolamide hydrochloride chemical structure, C8H13ClN2O4S3, CAS 164455-27-0
N-Deethyldorzolamide hydrochloride
CAS 164455-27-0C8H13ClN2O4S3
N-Deethyldorzolamide chemical structure, C8H12N2O4S3, CAS 154154-90-2
N-Deethyldorzolamide
CAS 154154-90-2C8H12N2O4S3
4-Chloro-5,6-dihydro-4H-thieno[2,3-b]thiopyran 7,7-dioxide chemical structure, C7H7ClO2S2, CAS 866131-06-8
4-Chloro-5,6-dihydro-4H-thieno[2,3-b]thiopyran 7,7-dioxide
CAS 866131-06-8C7H7ClO2S2
7,7-Dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol chemical structure, C7H8O3S2, CAS 137004-58-1
7,7-Dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol
CAS 137004-58-1C7H8O3S2
(7,7-Dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl) pentanoate chemical structure, C12H16O4S2, CAS 339018-99-4
(7,7-Dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl) pentanoate
CAS 339018-99-4C12H16O4S2
(7,7-Dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl) butanoate chemical structure, C11H14O4S2, CAS 339018-98-3
(7,7-Dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl) butanoate
CAS 339018-98-3C11H14O4S2
(7,7-Dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl) 2-methylpropanoate chemical structure, C11H14O4S2, CAS 339018-79-0
(7,7-Dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl) 2-methylpropanoate
CAS 339018-79-0C11H14O4S2
(7,7-Dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl) 2,2-dimethylpropanoate chemical structure, C12H16O4S2, CAS 339019-00-0
(7,7-Dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl) 2,2-dimethylpropanoate
CAS 339019-00-0C12H16O4S2
Dorzolamide chemical structure, C10H16N2O4S3, CAS 120279-96-1
Dorzolamide
CAS 120279-96-1C10H16N2O4S3
(4R,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide chemical structure, C10H16N2O4S3, CAS 120279-90-5
(4R,6S)-4-(Ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide
CAS 120279-90-5C10H16N2O4S3
Dorzolamide hydrochloride chemical structure, C10H17ClN2O4S3, CAS 130693-82-2
Dorzolamide hydrochloride
CAS 130693-82-2C10H17ClN2O4S3
(4S,6S)-N-Ethyl-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-amine chemical structure, C10H15NO2S2, CAS 403848-01-1
(4S,6S)-N-Ethyl-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-amine
CAS 403848-01-1C10H15NO2S2
N-[(4S,6S)-5,6-Dihydro-6-methyl-7,7-dioxido-4H-thieno[2,3-b]thiopyran-4-yl]-N-ethylacetamide chemical structure, C12H17NO3S2, CAS 403848-04-4
N-[(4S,6S)-5,6-Dihydro-6-methyl-7,7-dioxido-4H-thieno[2,3-b]thiopyran-4-yl]-N-ethylacetamide
CAS 403848-04-4C12H17NO3S2
rac-Cis Dorzolamide Hydrochloride chemical structure, C10H17ClN2O4S3
rac-Cis Dorzolamide Hydrochloride
C10H17ClN2O4S3
N-Ethyl-N-[(2S,4S)-2-methyl-1,1-dioxo-6-sulfamoyl-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-4-yl]acetamide chemical structure, C12H18N2O5S3, CAS 403848-09-9
N-Ethyl-N-[(2S,4S)-2-methyl-1,1-dioxo-6-sulfamoyl-2H,3H,4H-1lambda6-thieno[2,3-b]thiopyran-4-yl]acetamide
CAS 403848-09-9C12H18N2O5S3
N-((4R,6S)-6-Methyl-7,7-dioxido-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)acetamide chemical structure, C10H13NO3S2, CAS 148810-83-7
N-((4R,6S)-6-Methyl-7,7-dioxido-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-yl)acetamide
CAS 148810-83-7C10H13NO3S2