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Murcko scaffold

2-(Phenylsulfonyl)thiophene scaffold

84 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
84
With full pages
3
Scaffold SMILES

O=S(=O)(c1ccccc1)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Phenylsulfonyl)thiophene page
Murcko scaffold O=S(=O)(c1ccccc1)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 84 chemicals

5-(Benzenesulfonyl)thiophene-2-carboxylic acid chemical structure, C11H8O4S2, CAS 5324-78-7
5-(Benzenesulfonyl)thiophene-2-carboxylic acid
CAS 5324-78-7C11H8O4S2
2-Methyl-5-(phenylsulfonyl)thiophene chemical structure, C11H10O2S2, CAS 5324-81-2
2-Methyl-5-(phenylsulfonyl)thiophene
CAS 5324-81-2C11H10O2S2
2-Tosylthiophene chemical structure, C11H10O2S2, CAS 5713-57-5
2-Tosylthiophene
CAS 5713-57-5C11H10O2S2
2-(Phenylsulfonyl)thiophene chemical structure, C10H8O2S2, CAS 22407-40-5
2-(Phenylsulfonyl)thiophene
CAS 22407-40-5C10H8O2S2
N-[4-(5-Nitrothiophen-2-yl)sulfonylphenyl]acetamide chemical structure, C12H10N2O5S2, CAS 60516-05-4
N-[4-(5-Nitrothiophen-2-yl)sulfonylphenyl]acetamide
CAS 60516-05-4C12H10N2O5S2
2-(2,4,6-Trimethylphenyl)sulfonylthiophene chemical structure, C13H14O2S2, CAS 21991-08-2
2-(2,4,6-Trimethylphenyl)sulfonylthiophene
CAS 21991-08-2C13H14O2S2
5-(Phenylsulfonyl)-2-thiophenesulfonyl chloride chemical structure, C10H7ClO4S3, CAS 166964-37-0
5-(Phenylsulfonyl)-2-thiophenesulfonyl chloride
CAS 166964-37-0C10H7ClO4S3
RefChem:151665 chemical structure, C13H17ClN2O5S3, CAS 119731-75-8
RefChem:151665
CAS 119731-75-8C13H17ClN2O5S3
2-Amino-4-methyl-5-(4-methylphenyl)sulfonylthiophene-3-carbonitrile chemical structure, C13H12N2O2S2, CAS 728886-86-0
2-Amino-4-methyl-5-(4-methylphenyl)sulfonylthiophene-3-carbonitrile
CAS 728886-86-0C13H12N2O2S2
5-(Phenylsulfonyl)thiophene-2-Sulfonamide chemical structure, C10H9NO4S3, CAS 63032-70-2
5-(Phenylsulfonyl)thiophene-2-Sulfonamide
CAS 63032-70-2C10H9NO4S3
2-(Benzenesulfonyl)-5-nitrothiophene chemical structure, C10H7NO4S2, CAS 33786-85-5
2-(Benzenesulfonyl)-5-nitrothiophene
CAS 33786-85-5C10H7NO4S2
2-Thiophenesulfonamide,3-chloro-5-(phenylsulfonyl)- chemical structure, C10H8ClNO4S3, CAS 63032-98-4
2-Thiophenesulfonamide,3-chloro-5-(phenylsulfonyl)-
CAS 63032-98-4C10H8ClNO4S3
2-Thiophenesulfonamide,4-chloro-5-(phenylsulfonyl)- chemical structure, C10H8ClNO4S3, CAS 63033-09-0
2-Thiophenesulfonamide,4-chloro-5-(phenylsulfonyl)-
CAS 63033-09-0C10H8ClNO4S3
2-Thiophenesulfonamide,4-bromo-5-(phenylsulfonyl)- chemical structure, C10H8BrNO4S3, CAS 63032-82-6
2-Thiophenesulfonamide,4-bromo-5-(phenylsulfonyl)-
CAS 63032-82-6C10H8BrNO4S3
2-Thiophenesulfonamide,5-[(2-methylphenyl)sulfonyl]- chemical structure, C11H11NO4S3, CAS 63032-78-0
2-Thiophenesulfonamide,5-[(2-methylphenyl)sulfonyl]-
CAS 63032-78-0C11H11NO4S3
2-Thiophenesulfonamide,5-[(4-methylphenyl)sulfonyl]- chemical structure, C11H11NO4S3, CAS 63032-72-4
2-Thiophenesulfonamide,5-[(4-methylphenyl)sulfonyl]-
CAS 63032-72-4C11H11NO4S3
2-Thiophenesulfonamide,5-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]- chemical structure, C14H17NO4S3, CAS 63032-85-9
2-Thiophenesulfonamide,5-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-
CAS 63032-85-9C14H17NO4S3
2-Thiophenesulfonamide,5-[(3-fluorophenyl)sulfonyl]- chemical structure, C10H8FNO4S3, CAS 63033-14-7
2-Thiophenesulfonamide,5-[(3-fluorophenyl)sulfonyl]-
CAS 63033-14-7C10H8FNO4S3
2-Thiophenesulfonamide,5-[(4-fluorophenyl)sulfonyl]- chemical structure, C10H8FNO4S3, CAS 63032-79-1
2-Thiophenesulfonamide,5-[(4-fluorophenyl)sulfonyl]-
CAS 63032-79-1C10H8FNO4S3
2-Thiophenesulfonamide,5-[(4-chlorophenyl)sulfonyl]- chemical structure, C10H8ClNO4S3, CAS 63032-74-6
2-Thiophenesulfonamide,5-[(4-chlorophenyl)sulfonyl]-
CAS 63032-74-6C10H8ClNO4S3
2-Thiophenesulfonamide,5-[(4-bromophenyl)sulfonyl]- chemical structure, C10H8BrNO4S3, CAS 63032-73-5
2-Thiophenesulfonamide,5-[(4-bromophenyl)sulfonyl]-
CAS 63032-73-5C10H8BrNO4S3
2-Thiophenesulfonamide,5-[[3-(trifluoromethyl)phenyl]sulfonyl]- chemical structure, C11H8F3NO4S3, CAS 63032-86-0
2-Thiophenesulfonamide,5-[[3-(trifluoromethyl)phenyl]sulfonyl]-
CAS 63032-86-0C11H8F3NO4S3
2-Thiophenesulfonamide,5-[(4-methoxyphenyl)sulfonyl]- chemical structure, C11H11NO5S3, CAS 63032-71-3
2-Thiophenesulfonamide,5-[(4-methoxyphenyl)sulfonyl]-
CAS 63032-71-3C11H11NO5S3
5-(4-Hydroxyphenyl)sulfonylthiophene-2-sulfonamide chemical structure, C10H9NO5S3, CAS 63033-36-3
5-(4-Hydroxyphenyl)sulfonylthiophene-2-sulfonamide
CAS 63033-36-3C10H9NO5S3