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Murcko scaffold

2-(Pyrrolidin-3-yl)pyridine scaffold

217 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
217
With full pages
11
Scaffold SMILES

c1ccc(C2CCNC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyrrolidin-3-yl)pyridine page
Murcko scaffold c1ccc(C2CCNC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 217 chemicals

(3S,4S)-4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid dihydrochloride chemical structure, C10H14Cl2N2O2, CAS 1049739-70-9
(3S,4S)-4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid dihydrochloride
CAS 1049739-70-9C10H14Cl2N2O2
(3S,4S)-4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid chemical structure, C10H12N2O2, CAS 1049980-18-8
(3S,4S)-4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid
CAS 1049980-18-8C10H12N2O2
Boc-trans-4-(2-pyridinyl)-pyrrolidine-3-carboxylic acid chemical structure, C15H20N2O4, CAS 267876-09-5
Boc-trans-4-(2-pyridinyl)-pyrrolidine-3-carboxylic acid
CAS 267876-09-5C15H20N2O4
1,2-Dimethyl-3-(pyridin-2-yl)pyrrolidin-3-yl propanoate chemical structure, C14H20N2O2, CAS 69552-06-3
1,2-Dimethyl-3-(pyridin-2-yl)pyrrolidin-3-yl propanoate
CAS 69552-06-3C14H20N2O2
2-(Pyrrolidin-3-yl)pyridine chemical structure, C9H12N2, CAS 150281-45-1
2-(Pyrrolidin-3-yl)pyridine
CAS 150281-45-1C9H12N2
(2S,4S)-Methyl 4-(6-methoxypyridin-2-yl)pyrrolidine-2-carboxylate chemical structure, C12H16N2O3, CAS 835923-28-9
(2S,4S)-Methyl 4-(6-methoxypyridin-2-yl)pyrrolidine-2-carboxylate
CAS 835923-28-9C12H16N2O3
2-(3-(Pyridin-2-yl)pyrrolidin-3-yl)ethanol chemical structure, C11H16N2O, CAS 178372-19-5
2-(3-(Pyridin-2-yl)pyrrolidin-3-yl)ethanol
CAS 178372-19-5C11H16N2O
2-(3-Pyrrolidinyl)-3-pyridinamine chemical structure, C9H13N3, CAS 150281-48-4
2-(3-Pyrrolidinyl)-3-pyridinamine
CAS 150281-48-4C9H13N3
6-(1-Methyl-3-pyrrolidinyl)pyridin-2-amine chemical structure, C10H15N3, CAS 1378864-14-2
6-(1-Methyl-3-pyrrolidinyl)pyridin-2-amine
CAS 1378864-14-2C10H15N3
2-(3-Methylpyrrolidin-3-yl)pyridine chemical structure, C10H14N2, CAS 732981-96-3
2-(3-Methylpyrrolidin-3-yl)pyridine
CAS 732981-96-3C10H14N2
Ethyl 4-(pyridin-2-yl)pyrrolidine-3-carboxylate chemical structure, C12H16N2O2, CAS 1601076-24-7
Ethyl 4-(pyridin-2-yl)pyrrolidine-3-carboxylate
CAS 1601076-24-7C12H16N2O2
1-[(tert-Butoxy)carbonyl]-4-(pyridin-2-yl)pyrrolidine-3-carboxylic acid chemical structure, C15H20N2O4, CAS 1366983-15-4
1-[(tert-Butoxy)carbonyl]-4-(pyridin-2-yl)pyrrolidine-3-carboxylic acid
CAS 1366983-15-4C15H20N2O4
tert-Butyl 3-amino-4-(pyridin-2-yl)pyrrolidine-1-carboxylate chemical structure, C14H21N3O2, CAS 1367104-96-8
tert-Butyl 3-amino-4-(pyridin-2-yl)pyrrolidine-1-carboxylate
CAS 1367104-96-8C14H21N3O2
(R)-2-(Pyrrolidin-3-yl)pyridine chemical structure, C9H12N2, CAS 1008112-19-3
(R)-2-(Pyrrolidin-3-yl)pyridine
CAS 1008112-19-3C9H12N2
2-[(3S)-Pyrrolidin-3-yl]pyridine chemical structure, C9H12N2, CAS 1008112-18-2
2-[(3S)-Pyrrolidin-3-yl]pyridine
CAS 1008112-18-2C9H12N2
2-Bromo-6-(pyrrolidin-3-yl)pyridine chemical structure, C9H11BrN2, CAS 1159820-75-3
2-Bromo-6-(pyrrolidin-3-yl)pyridine
CAS 1159820-75-3C9H11BrN2
2-(Pyrrolidin-3-yl)pyridine hydrochloride chemical structure, C9H13ClN2, CAS 1198416-89-5
2-(Pyrrolidin-3-yl)pyridine hydrochloride
CAS 1198416-89-5C9H13ClN2
(rac-Trans)-1-tert-butyl 3-methyl 4-(5,6-dimethoxypyridin-2-yl)pyrrolidine-1,3-dicarboxylate chemical structure, C18H26N2O6, CAS 1217674-57-1
(rac-Trans)-1-tert-butyl 3-methyl 4-(5,6-dimethoxypyridin-2-yl)pyrrolidine-1,3-dicarboxylate
CAS 1217674-57-1C18H26N2O6
(3R,4R)-1-tert-Butyl 3-methyl 4-(6-chloro-5-pivalamidopyridin-2-yl)pyrrolidine-1,3-dicarboxylate chemical structure, C21H30ClN3O5, CAS 1217607-90-3
(3R,4R)-1-tert-Butyl 3-methyl 4-(6-chloro-5-pivalamidopyridin-2-yl)pyrrolidine-1,3-dicarboxylate
CAS 1217607-90-3C21H30ClN3O5
(trans-Racemic)-1-tert-butyl 3-methyl 4-(5-bromo-3-methoxypyridin-2-yl)pyrrolidine-1,3-dicarboxylate chemical structure, C17H23BrN2O5, CAS 1217743-30-0
(trans-Racemic)-1-tert-butyl 3-methyl 4-(5-bromo-3-methoxypyridin-2-yl)pyrrolidine-1,3-dicarboxylate
CAS 1217743-30-0C17H23BrN2O5
4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid chemical structure, C10H12N2O2, CAS 1048333-66-9
4-(Pyridin-2-yl)pyrrolidine-3-carboxylic acid
CAS 1048333-66-9C10H12N2O2
5-Bromo-3-nitro-2-(pyrrolidin-3-yl)pyridine chemical structure, C9H10BrN3O2, CAS 1020253-22-8
5-Bromo-3-nitro-2-(pyrrolidin-3-yl)pyridine
CAS 1020253-22-8C9H10BrN3O2
trans-1-(tert-Butoxycarbonyl)-4-(pyridin-2-yl)pyrrolidine-3-carboxylic acid chemical structure, C15H20N2O4
trans-1-(tert-Butoxycarbonyl)-4-(pyridin-2-yl)pyrrolidine-3-carboxylic acid
C15H20N2O4
trans-tert-Butyl 3-amino-4-(pyridin-2-yl)pyrrolidine-1-carboxylate chemical structure, C14H21N3O2, CAS 2351002-30-5
trans-tert-Butyl 3-amino-4-(pyridin-2-yl)pyrrolidine-1-carboxylate
CAS 2351002-30-5C14H21N3O2