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Murcko scaffold

1-Phenyl-7H-pyrazolo[5,4-b]pyridin-6-one scaffold

28 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 16
Chemicals: 28
With full pages: 4

Scaffold SMILES

O=c1ccc2cnn(-c3ccccc3)c2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1-Phenyl-7H-pyrazolo[5,4-b]pyridin-6-one page

Murcko scaffold O=c1ccc2cnn(-c3ccccc3)c2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

[3,4-Dimethyl-1-(4-methylphenyl)-6-oxo-1,6-dihydro-7H-pyrazolo[3,4-b]pyridin-7-yl]acetic acid chemical structure, C17H17N3O3, CAS 1119449-99-8

[3,4-Dimethyl-1-(4-methylphenyl)-6-oxo-1,6-dihydro-7H-pyrazolo[3,4-b]pyridin-7-yl]acetic acid

CAS 1119449-99-8C₁₇H₁₇N₃O₃

Methyl 2-(4-(difluoromethyl)-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridin-7(6H)-yl)acetate chemical structure, C17H15F2N3O3, CAS 1018052-31-7

Methyl 2-(4-(difluoromethyl)-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridin-7(6H)-yl)acetate

CAS 1018052-31-7C₁₇H₁₅F₂N₃O₃

2-(4-(Difluoromethyl)-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridin-7(6H)-yl)acetic acid chemical structure, C16H13F2N3O3, CAS 1018052-39-5

2-(4-(Difluoromethyl)-3-methyl-6-oxo-1-phenyl-1H-pyrazolo[3,4-b]pyridin-7(6H)-yl)acetic acid

CAS 1018052-39-5C₁₆H₁₃F₂N₃O₃

3,4-Dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-6-ol chemical structure, C14H13N3O, CAS 17321-44-7

3,4-Dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-6-ol

CAS 17321-44-7C₁₄H₁₃N₃O

3-Methyl-6-oxo-1-phenyl-1H,6H,7H-pyrazolo[3,4-b]pyridine-5-carboxylic acid chemical structure, C14H11N3O3, CAS 81933-80-4

3-Methyl-6-oxo-1-phenyl-1H,6H,7H-pyrazolo[3,4-b]pyridine-5-carboxylic acid

CAS 81933-80-4C₁₄H₁₁N₃O₃

3-Methyl-6-oxo-1-phenyl-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile chemical structure, C14H10N4O, CAS 52217-38-6

3-Methyl-6-oxo-1-phenyl-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

CAS 52217-38-6C₁₄H₁₀N₄O

Ethyl 4-amino-1-(3-fluorophenyl)-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C15H13FN4O3, CAS 2089391-68-2

Ethyl 4-amino-1-(3-fluorophenyl)-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carboxylate

CAS 2089391-68-2C₁₅H₁₃FN₄O₃

4-(Difluoromethyl)-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-6(7H)-one chemical structure, C14H11F2N3O, CAS 832746-77-7

4-(Difluoromethyl)-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-6(7H)-one

CAS 832746-77-7C₁₄H₁₁F₂N₃O

Ethyl 1-(4-methoxyphenyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C17H17N3O4, CAS 1160246-05-8

Ethyl 1-(4-methoxyphenyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylate

CAS 1160246-05-8C₁₇H₁₇N₃O₄

Ethyl 1-(2-fluorophenyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C16H14FN3O3, CAS 1160246-08-1

Ethyl 1-(2-fluorophenyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylate

CAS 1160246-08-1C₁₆H₁₄FN₃O₃

1-(4-Methoxyphenyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C15H13N3O4, CAS 1160246-11-6

1-(4-Methoxyphenyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

CAS 1160246-11-6C₁₅H₁₃N₃O₄

Ethyl 3-methyl-6-oxo-1-phenyl-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylate chemical structure, C16H15N3O3, CAS 1160246-14-9

Ethyl 3-methyl-6-oxo-1-phenyl-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylate

CAS 1160246-14-9C₁₆H₁₅N₃O₃

1-(2-Fluorophenyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid chemical structure, C14H10FN3O3, CAS 1160246-27-4

1-(2-Fluorophenyl)-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

CAS 1160246-27-4C₁₄H₁₀FN₃O₃

5-Bromo-1-(2,4-difluorophenyl)-1H-pyrazolo[3,4-B]pyridin-6(7H)-one chemical structure, C12H6BrF2N3O, CAS 1080573-41-6

5-Bromo-1-(2,4-difluorophenyl)-1H-pyrazolo[3,4-B]pyridin-6(7H)-one

CAS 1080573-41-6C₁₂H₆BrF₂N₃O

5-Chloro-4-(chloromethyl)-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-6(7H)-one chemical structure, C14H11Cl2N3O, CAS 938001-12-8

5-Chloro-4-(chloromethyl)-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-6(7H)-one

CAS 938001-12-8C₁₄H₁₁Cl₂N₃O

4-Amino-1-phenyl-7H-pyrazolo[5,4-b]pyridin-6-one chemical structure, C12H10N4O, CAS 344792-03-6

4-Amino-1-phenyl-7H-pyrazolo[5,4-b]pyridin-6-one

CAS 344792-03-6C₁₂H₁₀N₄O

5-Bromo-1-phenyl-1H-pyrazolo[3,4-b]pyridin-6(7H)-one chemical structure, C12H8BrN3O, CAS 344792-00-3

5-Bromo-1-phenyl-1H-pyrazolo[3,4-b]pyridin-6(7H)-one

CAS 344792-00-3C₁₂H₈BrN₃O

1-Phenyl-7H-pyrazolo[5,4-b]pyridin-6-one chemical structure, C12H9N3O, CAS 344791-99-7

1-Phenyl-7H-pyrazolo[5,4-b]pyridin-6-one

CAS 344791-99-7C₁₂H₉N₃O

5-(Aminomethyl)-3-methyl-1-phenyl-1H,6H,7H-pyrazolo[3,4-b]pyridin-6-one chemical structure, C14H14N4O, CAS 1181245-09-9

5-(Aminomethyl)-3-methyl-1-phenyl-1H,6H,7H-pyrazolo[3,4-b]pyridin-6-one

CAS 1181245-09-9C₁₄H₁₄N₄O

5-Bromo-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one chemical structure, C12H7BrFN3O, CAS 1220512-76-4

5-Bromo-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one

CAS 1220512-76-4C₁₂H₇BrFN₃O

1-(2-Fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one chemical structure, C12H8FN3O, CAS 1437436-01-5

1-(2-Fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one

CAS 1437436-01-5C₁₂H₈FN₃O

5-Chloro-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one chemical structure, C12H7ClFN3O, CAS 1437453-65-0

5-Chloro-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one

CAS 1437453-65-0C₁₂H₇ClFN₃O

1-(2,6-Difluorophenyl)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one chemical structure, C12H7F2N3O, CAS 1437432-53-5

1-(2,6-Difluorophenyl)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one

CAS 1437432-53-5C₁₂H₇F₂N₃O

1-(4-Fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one chemical structure, C12H8FN3O, CAS 1437385-43-7

1-(4-Fluorophenyl)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one

CAS 1437385-43-7C₁₂H₈FN₃O